Molecular mechanisms controlling the cell cycle in embryonic stem cells. (Q38129768)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23955576%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Molecular mechanisms controlling the cell cycle in embryonic stem cells (English)

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7 March 2020

1

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7 March 2020

author name string

Essam M Abdelalim

series ordinal

1

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29 August 2017

language of work or name

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1 December 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23955576%20AND%20SRC:MED&resulttype=core&format=json

Stem Cell Reviews and Reports

7 March 2020

published in

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29 August 2017

volume

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23955576%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

issue

6

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7 March 2020

page(s)

764-773

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23955576%20AND%20SRC:MED&resulttype=core&format=json

Establishment in culture of pluripotential cells from mouse embryos

7 March 2020

cites work

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Embryonic stem cell lines derived from human blastocysts

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Pluripotent cell division cycles are driven by ectopic Cdk2, cyclin A/E and E2F activities

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Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase

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Cell cycle control of embryonic stem cells

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Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a).

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Cell-cycle regulation in embryonic stem cells: centrosomal decisions on self-renewal

21 January 2018

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Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells

21 January 2018

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A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity

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Cell cycle and developmental regulations of replication factors in mouse embryonic stem cells.

21 January 2018

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Signalling, cell cycle and pluripotency in embryonic stem cells

21 January 2018

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Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

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The abbreviated pluripotent cell cycle.

21 January 2018

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Cyclin-dependent kinase 4/6 (cdk4/6) inhibitors: perspectives in cancer therapy and imaging.

21 January 2018

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Cell cycle regulation by microRNAs in stem cells

21 January 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

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Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming

21 January 2018

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Mechanisms of stem cell self-renewal

21 January 2018

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Transient inhibition of cell proliferation does not compromise self-renewal of mouse embryonic stem cells

21 January 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

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Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells.

21 January 2018

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An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells

21 January 2018

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Cdk2 inhibition prolongs G1 phase progression in mouse embryonic stem cells.

21 January 2018

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RB, the conductor that orchestrates life, death and differentiation

21 January 2018

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

The retinoblastoma tumor suppressor and stem cell biology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Cell cycle features of primate embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Keeping an eye on retinoblastoma control of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

The p53 inhibitor, pifithrin-α, suppresses self-renewal of embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Survival responses of human embryonic stem cells to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Repression of protein synthesis by miRNAs: how many mechanisms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Characterization of Dicer-deficient murine embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

microRNAs regulate human embryonic stem cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

A bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

CtBP-interacting BTB zinc finger protein (CIBZ) promotes proliferation and G1/S transition in embryonic stem cells via Nanog

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

5-Aminoimidazole-4-carboxyamide ribonucleoside induces G(1)/S arrest and Nanog downregulation via p53 and enhances erythroid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Inhibition of the ATR/Chk1 pathway induces a p38-dependent S-phase delay in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

BNP signaling is crucial for embryonic stem cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Proteomic analyses reveal common promiscuous patterns of cell surface proteins on human embryonic stem cells and sperms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

NPR-A regulates self-renewal and pluripotency of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Cell cycle-dependent calcium oscillations in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Estrogen controls embryonic stem cell proliferation via store-operated calcium entry and the nuclear factor of activated T-cells (NFAT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

CBARA1 plays a role in stemness and proliferation of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

G1 to S phase cell cycle transition in somatic and embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Cell cycle regulation by MicroRNAs in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Oct-4 controls cell-cycle progression of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Oct4 targets regulatory nodes to modulate stem cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

p63 deficiency activates a program of cellular senescence and leads to accelerated aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Myc represses primitive endoderm differentiation in pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

An extended transcriptional network for pluripotency of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

myc maintains embryonic stem cell pluripotency and self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Cyclin-dependent kinase 2-associating protein 1 commits murine embryonic stem cell differentiation through retinoblastoma protein regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Regulation of Nanog Expression by Phosphoinositide 3-Kinase-dependent Signaling in Murine Embryonic Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

Gap 1 phase length and mouse embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-013-9469-9

P53-dependent and -independent links between DNA-damage, apoptosis and mutation frequency in ES cells

21 January 2018

1 reference

12 December 2020

Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability

1 reference

12 December 2020

Human embryonic stem cells are capable of executing G1/S checkpoint activation.

1 reference

12 December 2020

Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells

1 reference

12 December 2020

Regulation of apoptosis and differentiation by p53 in human embryonic stem cells

1 reference

12 December 2020

Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells

1 reference

12 December 2020

10.1007/S12015-013-9469-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23955576%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 March 2020

1042583785

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23955576%20AND%20SRC:MED&resulttype=core&format=json