Nonclassical hedgehog-GLI signaling and its clinical implications (Q38127609)

29 August 2017

title

Nonclassical hedgehog-GLI signaling and its clinical implications (English)

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29 August 2017

Lalita A Shevde

1

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29 August 2017

Rajeev S Samant

series ordinal

2

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29 August 2017

language of work or name

English

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publication date

11 September 2013

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International Journal of Cancer

29 August 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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29 August 2017

volume

135

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29 August 2017

issue

1

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29 August 2017

page(s)

1-6

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Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins

29 August 2017

cites work

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Sonic hedgehog promotes desmoplasia in pancreatic cancer

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Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis.

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The crosstalk of mTOR/S6K1 and Hedgehog pathways

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Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer

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Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.

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Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer

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Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer

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Increased vascularity and spontaneous metastasis of breast cancer by hedgehog signaling mediated upregulation of cyr61

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Smoothened Antagonists Reverse Taxane Resistance in Ovarian Cancer

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Stem cell pathways contribute to clinical chemoresistance in ovarian cancer

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Expression of the glioma-associated oncogene homolog 1 (gli1) in advanced serous ovarian cancer is associated with unfavorable overall survival

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Hedgehog signaling in prostate cancer

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Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

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Hedgehog signalling in prostate regeneration, neoplasia and metastasis

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SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway

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Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

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Aberrant expression of sonic hedgehog pathway in colon cancer and melanosis coli.

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Noncanonical regulation of the Hedgehog mediator GLI1 by c-MYC in Burkitt lymphoma

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Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation.

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HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

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A small molecule that binds Hedgehog and blocks its signaling in human cells

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Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling

21 January 2018

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Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

21 January 2018

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Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

21 January 2018

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Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

21 January 2018

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TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling

21 January 2018

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Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells

21 January 2018

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Nonclassical activation of Hedgehog signaling enhances multidrug resistance and makes cancer cells refractory to Smoothened-targeting Hedgehog inhibition

21 January 2018

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GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.

21 January 2018

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Therapeutic inhibition of Hedgehog-GLI signaling in cancer: epithelial, stromal, or stem cell targets?

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Targeting Hedgehog--a cancer stem cell pathway

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.28424

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29 August 2017

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