Epidermal growth factor receptor as a therapeutic target in glioblastoma (Q38098098)

28 August 2017

title

Epidermal growth factor receptor as a therapeutic target in glioblastoma (English)

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28 August 2017

B Kalman

1

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28 August 2017

E Szep

series ordinal

2

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28 August 2017

F Garzuly

series ordinal

3

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28 August 2017

D E Post

series ordinal

4

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28 August 2017

publication date

11 April 2013

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28 August 2017

published in

NeuroMolecular Medicine

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28 August 2017

volume

15

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28 August 2017

issue

2

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28 August 2017

page(s)

420-434

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Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells

28 August 2017

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Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3

21 January 2018

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Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines

21 January 2018

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21 January 2018

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Marked inhibition of glioblastoma target cell tumorigenicity in vitro by retrovirus-mediated transfer of a hairpin ribozyme against deletion-mutant epidermal growth factor receptor messenger RNA.

21 January 2018

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21 January 2018

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MGMT gene silencing and benefit from temozolomide in glioblastoma

21 January 2018

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Epidermal growth factor receptor: a re-emerging target in glioblastoma

21 January 2018

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Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma

21 January 2018

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21 January 2018

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21 January 2018

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Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

21 January 2018

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21 January 2018

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Blockade of EGFR signaling promotes glioma stem-like cell invasiveness by abolishing ID3-mediated inhibition of p27(KIP1) and MMP3 expression

21 January 2018

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Molecular characterization of EGFR and EGFRvIII signaling networks in human glioblastoma tumor xenografts

21 January 2018

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Suppression of EGFR expression by antisense or small interference RNA inhibits U251 glioma cell growth in vitro and in vivo

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cooperative Hedgehog-EGFR signaling

21 January 2018

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Low HER2-expressing glioblastomas are more often secondary to anaplastic transformation of low-grade glioma

21 January 2018

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RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls

21 January 2018

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21 January 2018

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Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme

21 January 2018

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Lipomatous supratentorial primitive neuroectodermal tumor with glioblastomatous differentiation.

21 January 2018

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Radioimmunotherapy as a novel treatment regimen: 125I-labeled monoclonal antibody 425 in the treatment of high-grade brain gliomas

21 January 2018

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21 January 2018

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A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy

21 January 2018

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21 January 2018

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21 January 2018

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Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway

21 January 2018

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An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme

21 January 2018

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A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors

21 January 2018

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Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

21 January 2018

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Superselective intra-arterial cerebral infusion of novel agents after blood-brain disruption for the treatment of recurrent glioblastoma multiforme: a technical case series

21 January 2018

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Inhibition of glioma growth by tumor-specific activation of double-stranded RNA-dependent protein kinase PKR.

21 January 2018

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21 January 2018

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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

21 January 2018

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On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells

21 January 2018

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Maintenance of EGFR and EGFRvIII expressions in an in vivo and in vitro model of human glioblastoma multiforme

21 January 2018

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

21 January 2018

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

21 January 2018

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

21 January 2018

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Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance

21 January 2018

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Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end?

21 January 2018

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Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Spontaneous activation and signaling by overexpressed epidermal growth factor receptors in glioblastoma cells

21 January 2018

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Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

21 January 2018

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Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034.

21 January 2018

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21 January 2018

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

21 January 2018

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21 January 2018

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21 January 2018

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Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas

21 January 2018

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21 January 2018

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The development of HKI-272 and related compounds for the treatment of cancer

21 January 2018

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Inhibition of Tumor Growth by Ribozyme-Mediated Suppression of Aberrant Epidermal Growth Factor Receptor Gene Expression

21 January 2018

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IDH1 and IDH2 mutations in gliomas

21 January 2018

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Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy

21 January 2018

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The monoclonal antibody CH12 enhances the sorafenib-mediated growth inhibition of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III

21 January 2018

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Antitumor activity of a novel antisense oligonucleotide against Akt1.

21 January 2018

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Safety and efficacy of erlotinib in first-relapse glioblastoma: a phase II open-label study

21 January 2018

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The constitutive activity of epidermal growth factor receptor vIII leads to activation and differential trafficking of wild-type epidermal growth factor receptor and erbB2

21 January 2018

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Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

21 January 2018

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Coexpression of c-erbB 1-4 receptor proteins in human glioblastomas. An immunohistochemical study.

21 January 2018

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12 December 2020

Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme

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12 December 2020

Glioma revisited: from neurogenesis and cancer stem cells to the epigenetic regulation of the niche

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12 December 2020

The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches

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12 December 2020

Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice.

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12 December 2020

Mini-review: bmx kinase inhibitors for cancer therapy.

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12 December 2020

A novel hybrid peptide targeting EGFR-expressing cancers

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12 December 2020

Rindopepimut, a 14-mer injectable peptide vaccine against EGFRvIII for the potential treatment of glioblastoma multiforme

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12 December 2020

The Efficacy of Epidermal Growth Factor Receptor-Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization

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12 December 2020

Brain tumor therapy by combined vaccination and antisense oligonucleotide delivery with nanoparticles

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12 December 2020

Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR.

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12 December 2020

MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells.

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12 December 2020

Current status of immunotherapy and gene therapy for high-grade gliomas

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12 December 2020

Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial

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12 December 2020

RNA interference therapeutics for cancer: challenges and opportunities (review).

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12 December 2020

Anti-epidermal growth factor receptor monoclonal antibody cetuximab augments radiation effects in glioblastoma multiforme in vitro and in vivo

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12 December 2020

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

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12 December 2020

Gli proteins encode context-dependent positive and negative functions: implications for development and disease

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12 December 2020

Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase

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12 December 2020

Rindopepimut: an evidence-based review of its therapeutic potential in the treatment of EGFRvIII-positive glioblastoma

1 reference

12 December 2020

10.1007/S12017-013-8229-Y

Identifiers

DOI

1 reference

Dimensions Publication ID

28 August 2017

1030022927

0 references

1 reference