Potential role for statins in sickle cell disease (Q38071047)

28 August 2017

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title

Potential role for statins in sickle cell disease (English)

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28 August 2017

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Soheir S Adam

1

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28 August 2017

Carolyn Hoppe

series ordinal

2

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28 August 2017

publication date

31 December 2012

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28 August 2017

published in

Pediatric Blood & Cancer

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28 August 2017

volume

60

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28 August 2017

issue

4

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28 August 2017

page(s)

550-557

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Pleiotropic effects of statins: evidence for benefits beyond LDL-cholesterol lowering

28 August 2017

cites work

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Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions

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Tissue factor expression by endothelial cells in sickle cell anemia

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Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury

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The low cholesterol-mortality association in a national cohort

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Low total cholesterol and increased risk of dying: are low levels clinical warning signs in the elderly? Results from the Italian Longitudinal Study on Aging

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Hypocholesterolemia is a significant predictor of death in a cohort of chronic hemodialysis patients

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A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction

21 January 2018

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Statins as potent antiinflammatory drugs

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Native LDL-cholesterol mediated monocyte adhesion molecule overexpression is blocked by simvastatin.

21 January 2018

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HMG-CoA reductase inhibitors reduce adhesion of human monocytes to endothelial cells

21 January 2018

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Simvastatin reduces VCAM-1 expression in human umbilical vein endothelial cells exposed to lipopolysaccharide

21 January 2018

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Statins inhibit C-reactive protein-induced chemokine secretion, ICAM-1 upregulation and chemotaxis in adherent human monocytes

21 January 2018

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Simvastatin exerts both anti-inflammatory and cardioprotective effects in apolipoprotein E-deficient mice.

21 January 2018

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Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein

21 January 2018

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Hypoxia/reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice

21 January 2018

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Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models

21 January 2018

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beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae

21 January 2018

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Age-associated inflammation and toll-like receptor dysfunction prime the lungs for pneumococcal pneumonia

21 January 2018

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Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease

21 January 2018

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Sickle cell disease and stroke

21 January 2018

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Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality

21 January 2018

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Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin

21 January 2018

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Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin

21 January 2018

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Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes

21 January 2018

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Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease

21 January 2018

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Effects of losartan and simvastatin on monocyte-derived microparticles in hypertensive patients with and without type 2 diabetes mellitus

21 January 2018

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The effects of pitavastatin, eicosapentaenoic acid and combined therapy on platelet-derived microparticles and adiponectin in hyperlipidemic, diabetic patients

21 January 2018

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Hypercoagulability in sickle cell disease: a curious paradox

21 January 2018

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Primary prophylaxis with warfarin prevents thrombosis in paroxysmal nocturnal hemoglobinuria (PNH).

21 January 2018

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Erythrocyte hemolysis and hemoglobin oxidation promote ferric chloride-induced vascular injury

21 January 2018

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Role of oxidative stress and nitric oxide in atherothrombosis

21 January 2018

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Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

21 January 2018

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Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?

21 January 2018

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Nitric oxide's reactions with hemoglobin: a view through the SNO-storm

21 January 2018

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Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation

21 January 2018

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Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease

21 January 2018

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Iron nitrosyl hemoglobin formation from the reactions of hemoglobin and hydroxyurea

21 January 2018

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Nitric Oxide Generation from Hydroxyurea via Copper‐catalyzed Peroxidation and Implications for Pharmacological Actions of Hydroxyurea

21 January 2018

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Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase

21 January 2018

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Long-term safety and efficacy profile of simvastatin

21 January 2018

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Rhabdomyolysis and acute renal failure due to combination therapy with simvastatin and warfarin

21 January 2018

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Rhabdomyolysis induced by a single dose of a statin

21 January 2018

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Acute rhabdomyolysis associated with cerivastatin therapy

21 January 2018

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21 January 2018

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Myopathy and rhabdomyolysis with lipid-lowering drugs

21 January 2018

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The myotoxicity of statins

21 January 2018

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Statin use and risk of depression in patients with coronary heart disease: longitudinal data from the Heart and Soul Study

21 January 2018

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Screening for statin-related toxicity: the yield of transaminase and creatine kinase measurements in a primary care setting

21 January 2018

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Statin therapy in kidney disease populations: potential benefits beyond lipid lowering and the need for clinical trials

21 January 2018

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Plasma lipids in Iranians with sickle cell disease: hypocholesterolemia in sickle cell anemia and increase of HDL-cholesterol in sickle cell trait

21 January 2018

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Hypocholesterolemia in Nigerian children with sickle cell disease

21 January 2018

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Hypocholesterolemia in children and adolescents with beta-thalassemia intermedia

21 January 2018

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Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes: the MIRACL study: a randomized controlled trial

21 January 2018

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Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: the LIPID trial follow-up

21 January 2018

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Safety and tolerability of pravastatin in long-term clinical trials: prospective Pravastatin Pooling (PPP) Project

21 January 2018

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Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial

21 January 2018

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Safety and efficacy of achieving very low low-density lipoprotein cholesterol levels with rosuvastatin 40 mg daily (from the ASTEROID Study).

21 January 2018

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Rosuvastatin in the prevention of stroke among men and women with elevated levels of C-reactive protein: justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER).

21 January 2018

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ACP Journal Club. Rosuvastatin prevented major cardiovascular events in persons with elevated C-reactive protein

21 January 2018

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Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TEXCAPS): additional perspectives on tolerability of long-term treatment with lovastatin

21 January 2018

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Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up

21 January 2018

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Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PBC.24443

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28 August 2017

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