Disease modelling using induced pluripotent stem cells: status and prospects (Q38059468)

28 August 2017

title

Disease modelling using induced pluripotent stem cells: status and prospects (English)

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28 August 2017

Oz Pomp

1

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28 August 2017

Alan Colman

series ordinal

2

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28 August 2017

language of work or name

English

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publication date

13 November 2012

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28 August 2017

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28 August 2017

volume

35

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28 August 2017

issue

3

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28 August 2017

page(s)

271-280

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Embryonic stem cell lines derived from human blastocysts

28 August 2017

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Virus-free induction of pluripotency and subsequent excision of reprogramming factors

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Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

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Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

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Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells

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Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture

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Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

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Memory in Induced Pluripotent Stem Cells: Reprogrammed Human Retinal-Pigmented Epithelial Cells Show Tendency for Spontaneous Redifferentiation

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Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation

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Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

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Erosion of dosage compensation impacts human iPSC disease modeling

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Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes

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Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

21 January 2018

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X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations

21 January 2018

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Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome

21 January 2018

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A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

21 January 2018

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Unexpected X Chromosome Skewing during Culture and Reprogramming of Human Somatic Cells Can Be Alleviated by Exogenous Telomerase

21 January 2018

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Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model

21 January 2018

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Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

21 January 2018

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Female human iPSCs retain an inactive X chromosome

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Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells

21 January 2018

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Metastable pluripotent states in NOD-mouse-derived ESCs

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A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.

21 January 2018

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Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1

21 January 2018

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Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells

21 January 2018

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Harnessing the potential of induced pluripotent stem cells for regenerative medicine

21 January 2018

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21 January 2018

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Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells

21 January 2018

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Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

21 January 2018

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A functionally characterized test set of human induced pluripotent stem cells

21 January 2018

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Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

21 January 2018

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 January 2018

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Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells

21 January 2018

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miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells

21 January 2018

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Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

21 January 2018

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Identification and characterization of a spinal muscular atrophy-determining gene

21 January 2018

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Modeling oculopharyngeal muscular dystrophy in myotube cultures reveals reduced accumulation of soluble mutant PABPN1 protein

21 January 2018

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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

21 January 2018

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MeCP2, a key contributor to neurological disease, activates and represses transcription

21 January 2018

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Postnatal Neurodevelopmental Disorders: Meeting at the Synapse?

21 January 2018

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Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia

21 January 2018

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Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

21 January 2018

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Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

21 January 2018

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Modelling schizophrenia using human induced pluripotent stem cells

21 January 2018

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A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects

21 January 2018

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Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

21 January 2018

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Constructing and Deconstructing Stem Cell Models of Neurological Disease

21 January 2018

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Comparative Analysis of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cells Reveals Current Drawbacks and Possible Strategies for Improved Differentiation

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

New approaches in the therapy of cardiomyopathy in muscular dystrophy

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

The ground state of embryonic stem cell self-renewal

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

The dark side of induced pluripotency

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIES.201200088

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28 August 2017

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