Inhibition of cholesterol absorption: targeting the intestine. (Q38038125)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Inhibition of cholesterol absorption: targeting the intestine (English)

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12 February 2020

1

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12 February 2020

Pavel Gershkovich

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

4

Kishor M Wasan

1 reference

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12 February 2020

3

Jerald W Darlington

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12 February 2020

publication date

25 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

published in

Pharmaceutical Research

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12 February 2020

volume

29

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12 February 2020

issue

12

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12 February 2020

page(s)

3235-3250

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Global cardiovascular health: urgent need for an intersectoral approach

12 February 2020

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Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood

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Selectivity of pyripyropene derivatives in inhibition toward acyl-CoA:cholesterol acyltransferase 2 isozyme.

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Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery

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A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors

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https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Hepatic and intestinal changes in rats treated with T-0126, a microsomal triglyceride transfer protein (mtp) inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

A Small-Molecule Inhibitor of Enterocytic Microsomal Triglyceride Transfer Protein, SLx-4090: Biochemical, Pharmacodynamic, Pharmacokinetic, and Safety Profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Intestinal assembly and secretion of highly dense/lipid-poor apolipoprotein B48-containing lipoprotein particles in the fasting state: evidence for induction by insulin resistance and exogenous fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The ever-expanding role of degradation in the regulation of apolipoprotein B metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The degradation of apolipoprotein B100: multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The forgotten majority: unfinished business in cardiovascular risk reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Macrophages in the pathogenesis of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Obesity, inflammation, and atherosclerosis

21 January 2018

1 reference

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High-density lipoprotein and coronary heart disease: current and future therapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: results of the NHLBI Type II Coronary Intervention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Add-on therapy for hypercholesterolemia: a pilot comparison of two gastrointestinally-acting agents in statin-treated patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

New lipid modulating drugs: the role of microsomal transport protein inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Dietary fibers: V. Binding of bile salts, phospholipids and cholesterol from mixed micelles by bile acid sequestrants and dietary fibers

21 January 2018

1 reference

12 December 2020

A physiological method for estimation of hepatic secretion of biliary lipids in man

1 reference

12 December 2020

Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines

1 reference

12 December 2020

Disodium Ascorbyl Phytostanyl Phosphates (FM-VP4) reduces plasma cholesterol concentration, body weight and abdominal fat gain within a dietary-induced obese mouse model

1 reference

12 December 2020

Cholesterol absorption efficiency declines at moderate dietary doses in normal human subjects.

1 reference

12 December 2020

Safety of statins: focus on clinical pharmacokinetics and drug interactions

1 reference

12 December 2020

Assessing plasma lipid levels, body weight, and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils

1 reference

12 December 2020

Intracellular apoA-I and apoB distribution in rat intestine is altered by lipid feeding.

1 reference

12 December 2020

Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver

1 reference

12 December 2020

A comparison of hypocholesterolemic activity of beta-sitosterol and beta-sitostanol in rats

1 reference

12 December 2020

NEW CONTRIBUTIONS IN STEROL METABOLISM

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12 December 2020

Cholesterol absorption efficiency regulates plasma cholesterol level in the Finnish population

1 reference

12 December 2020

ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS).

1 reference

12 December 2020

Dietary fiber intake in relation to coronary heart disease and all-cause mortality over 40 y: the Zutphen Study

1 reference

12 December 2020

Inhibition of cholesterol absorption in rats by plant sterols

1 reference

12 December 2020

Coronary heart disease in seven countries. I. The study program and objectives

1 reference

12 December 2020

Direct evidence for a two-step assembly of ApoB48-containing lipoproteins in the lumen of the smooth endoplasmic reticulum of rabbit enterocytes

1 reference

12 December 2020

Colesevelam hydrochloride (cholestagel): a new, potent bile acid sequestrant associated with a low incidence of gastrointestinal side effects

1 reference

12 December 2020

Effect of micellar beta-sitosterol on cholesterol metabolism in CaCo-2 cells

1 reference

12 December 2020

Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8

1 reference

12 December 2020

Effect of citrus pectin on blood lipids and fecal steroid excretion in man

1 reference

12 December 2020

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report

1 reference

12 December 2020

Long-term treatment of hypercholesterolaemia with a new palatable formulation of guar gum

1 reference

12 December 2020

Thermodynamic and molecular determinants of sterol solubilities in bile salt micelles

1 reference

12 December 2020

Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men

1 reference

12 December 2020

Dietary fibre and 10-year mortality from coronary heart disease, cancer, and all causes. The Zutphen study

1 reference

12 December 2020

Assessment of cholesterol absorption inhibitors nanostructured aluminosilicate and cholestyramine using in vitro lipolysis model

1 reference

12 December 2020

Effects of AOMA on cholesterol metabolism in man

1 reference

12 December 2020

Alternate pathways of bile acid synthesis in the cholesterol 7alpha-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding.

1 reference

12 December 2020

Low levels of viscous hydrocolloids lower plasma cholesterol in rats primarily by impairing cholesterol absorption

1 reference

12 December 2020

Effects of sucrose polyester on cholesterol metabolism in man

1 reference

12 December 2020

Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster

1 reference

12 December 2020

Influence of phytostanol phosphoryl ascorbate, FM-VP4, on pancreatic lipase activity and cholesterol accumulation within Caco-2 cells.

1 reference

12 December 2020

A double-blind, placebo-controlled study of sucrose polyester in hypercholesterolemic outpatients

1 reference

12 December 2020

The Effect of a Nonabsorbable Lipid, Sucrose Polyester, on the Absorption of Dietary Cholesterol by the Rat

1 reference

12 December 2020

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

1 reference

12 December 2020

Effects of colestipol alone and in combination with simvastatin on apolipoprotein B metabolism

1 reference

12 December 2020

Antisense oligonucleotides: basic concepts and mechanisms

1 reference

12 December 2020

Metabolic studies on the hypolipidaemic effect of guar gum

1 reference

12 December 2020

Primary hypercholesterolemia: effect of treatment on serum lipids, lipoprotein fractions, cholesterol absorption, sterol balance, and platelet aggregation

1 reference

12 December 2020

An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits

1 reference

12 December 2020

Effects of sitosterol and sitostanol on micellar solubility of cholesterol.

1 reference

12 December 2020

ACAT inhibition and the progression of coronary atherosclerosis

1 reference

12 December 2020

Effects of colesevelam hydrochloride on low-density lipoprotein cholesterol and high-sensitivity C-reactive protein when added to statins in patients with hypercholesterolemia

1 reference

12 December 2020

Cholesterol-lowering effects of dietary fiber: a meta-analysis

1 reference

12 December 2020

Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine

1 reference

12 December 2020

Effects of inhibiting cholesterol absorption and synthesis on cholesterol and lipoprotein metabolism in hypercholesterolemic non-insulin-dependent diabetic men

1 reference

12 December 2020

Effects of 2164U90 on ileal bile acid absorption and serum cholesterol in rats and mice

1 reference

12 December 2020

Cholesterol absorption in man: effect of administration of clofibrate and/or cholestyramine

1 reference

12 December 2020

Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry.

1 reference

12 December 2020

Hypertriglyceridemia: a contraindication to the use of bile acid binding resins

1 reference

12 December 2020

Intracellular events in the assembly of chylomicrons in rabbit enterocytes

1 reference

12 December 2020

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1 reference

12 December 2020

The Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in incidence of coronary heart disease

1 reference

12 December 2020

Normal plasma cholesterol in an 88-year-old man who eats 25 eggs a day. Mechanisms of adaptation

1 reference

12 December 2020

The pharmacokinetics and pharmacodynamics of agents proven to raise high-density lipoprotein cholesterol

1 reference

12 December 2020

Inhibition of cholesterol absorption by plant sterols for mass intervention

1 reference

12 December 2020

Dietary fibre: an agreed definition

1 reference

12 December 2020

Intestinal apolipoprotein A-I and B-48 metabolism: effects of sustained alterations in dietary triglyceride and mucosal cholesterol flux

1 reference

12 December 2020

Lowering of serum cholesterol by the administration of a plant sterol

1 reference

12 December 2020

Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis

1 reference

12 December 2020

Effect of colestipol on sterol metabolism in the rat

1 reference

12 December 2020

Interruption of the enterohepatic circulation of bile acids in man: comparative effects of cholestyramine and ileal exclusion on cholesterol metabolism

1 reference

12 December 2020

10.1007/S11095-012-0858-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference