Epithelial-mesenchymal transition, the tumor microenvironment, and metastatic behavior of epithelial malignancies. (Q38024791)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773954%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Epithelial-mesenchymal transition, the tumor microenvironment, and metastatic behavior of epithelial malignancies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773954%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Lindsay J Talbot

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773954%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Syamal D Bhattacharya

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773954%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Paul C Kuo

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773954%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

publication date

18 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773954%20AND%20SRC:MED&resulttype=core&format=json

International journal of biochemistry and molecular biology

7 February 2020

published in

1 reference

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7 February 2020

volume

3

1 reference

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7 February 2020

issue

2

1 reference

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7 February 2020

page(s)

117-136

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773954%20AND%20SRC:MED&resulttype=core&format=json

Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition

7 February 2020

cites work

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Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells

6 September 2017

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An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

6 September 2017

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The mechanisms of cancer immunoescape and development of overcoming strategies

6 September 2017

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Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations

6 September 2017

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SFRP1 reduction results in an increased sensitivity to TGF-β signaling

6 September 2017

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Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

6 September 2017

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Retracted: Up-Regulation of Sonic Hedgehog Contributes to TGF-β1-Induced Epithelial to Mesenchymal Transition in NSCLC Cells

6 September 2017

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Molecular signature of epithelial-mesenchymal transition (EMT) in human prostate cancer bone metastasis

6 September 2017

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The dynamic roles of TGF-β in cancer

6 September 2017

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Transforming growth factor-β and the hallmarks of cancer

6 September 2017

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Interactions between Hedgehog proteins and their binding partners come into view

6 September 2017

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The role of the tissue microenvironment in the regulation of cancer cell motility and invasion.

6 September 2017

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The role of serum response factor in hepatocellular carcinoma: Implications for disease progression

6 September 2017

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The role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancer

6 September 2017

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Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

6 September 2017

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Targeting Notch signaling pathway to overcome drug resistance for cancer therapy

6 September 2017

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6 September 2017

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Stromelysin-1 (MMP-3) is a target and a regulator of Wnt1-induced epithelial-mesenchymal transition (EMT)

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer.

6 September 2017

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A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

6 September 2017

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Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

6 September 2017

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A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer

6 September 2017

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6 September 2017

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6 September 2017

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Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia

6 September 2017

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Fibroblasts in cancer

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6 September 2017

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High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

6 September 2017

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Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks

6 September 2017

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Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

6 September 2017

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Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

6 September 2017

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Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

6 September 2017

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Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins

6 September 2017

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Critical determinants of metastasis

6 September 2017

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Regulation of cell proliferation by Smad proteins

6 September 2017

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Role of transforming growth factor beta in human disease

6 September 2017

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TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

6 September 2017

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Activation of Notch-1 enhances epithelial-mesenchymal transition in gefitinib-acquired resistant lung cancer cells

6 September 2017

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A novel human Smad4 mutation is involved in papillary thyroid carcinoma progression.

6 September 2017

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GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells

6 September 2017

1 reference

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A monoclonal antibody against human Notch1 ligand-binding domain depletes subpopulation of putative breast cancer stem-like cells

6 September 2017

1 reference

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Smad3 regulates E-cadherin via miRNA-200 pathway

6 September 2017

1 reference

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Notch2‐induced COX‐2 expression enhancing gastric cancer progression

6 September 2017

1 reference

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Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer

6 September 2017

1 reference

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Increased CD13 expression reduces reactive oxygen species, promoting survival of liver cancer stem cells via an epithelial-mesenchymal transition-like phenomenon

6 September 2017

1 reference

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Stabilization of phenotypic plasticity through mesenchymal-specific DNA hypermethylation in cancer cells

6 September 2017

1 reference

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Wnt2 secreted by tumour fibroblasts promotes tumour progression in oesophageal cancer by activation of the Wnt/β-catenin signalling pathway.

6 September 2017

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Notch signaling activated by replication stress-induced expression of midkine drives epithelial-mesenchymal transition and chemoresistance in pancreatic cancer

6 September 2017

1 reference

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The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Critical role of Wnt5a-Ror2 signaling in motility and invasiveness of carcinoma cells following Snail-mediated epithelial-mesenchymal transition

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Drug resistant MCF-7 cells exhibit epithelial-mesenchymal transition gene expression pattern

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Involvement of the Wnt-β-catenin pathway in invasion and migration of oral squamous carcinoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Smad signaling is required to maintain epigenetic silencing during breast cancer progression.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Epigenetic alterations of CDH1 and APC genes: relationship with activation of Wnt/beta-catenin pathway in invasive ductal carcinoma of breast.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Role of Wnt/beta-catenin signaling pathway in epithelial-mesenchymal transition of human prostate cancer induced by hypoxia-inducible factor-1alpha

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Snail-regulated genes in malignant melanoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

twist and snail as positive and negative regulators during Drosophila mesoderm development.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Differential expression of hedgehog signaling components and Snail/E-cadherin in human brain tumors

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Promoter-wide analysis of Smad4 binding sites in human epithelial cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

Interaction of embryonic surface and cytoskeleton with extracellular matrix

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388731

miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition

31 August 2018

1 reference

12 December 2020

Evaluation of glioma-associated oncogene 1 expression and its correlation with the expression of sonic hedgehog, E-cadherin and S100a4 in human hepatocellular carcinoma

1 reference

12 December 2020

Wnt-dependent regulation of the E-cadherin repressor snail

1 reference

12 December 2020

Tumor induction of VEGF promoter activity in stromal cells

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773954%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

22773954

1 reference