Mouse as a model for multifactorial inheritance of neural tube defects (Q38018292)

27 August 2017

title

Mouse as a model for multifactorial inheritance of neural tube defects (English)

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27 August 2017

Irene E Zohn

1

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27 August 2017

publication date

1 June 2012

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Birth Defects Research Part C: Embryo Today Reviews

27 August 2017

published in

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27 August 2017

volume

96

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27 August 2017

issue

2

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27 August 2017

page(s)

193-205

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Planar signaling and morphogenesis in Drosophila

27 August 2017

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Crooked tail (Cd) models human folate-responsive neural tube defects

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Increased mRNA levels of Mn-SOD and catalase in embryos of diabetic rats from a malformation-resistant strain.

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Maternal diabetes increases the risk of caudal regression caused by retinoic acid.

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Oxidant regulation of gene expression and neural tube development: Insights gained from diabetic pregnancy on molecular causes of neural tube defects

21 January 2018

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Diabetes and apoptosis: neural crest cells and neural tube.

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Waardenburg syndrome and myelomeningocele in a family

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Prenatal sonographic features of fetuses in trisomy 13 pregnancies (II).

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Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

21 January 2018

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Prevention of spinal neural tube defects in the curly tail mouse mutant by a specific effect of retinoic acid.

21 January 2018

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Formation and differentiation of the avian sclerotome

21 January 2018

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Changes with gestational age in the nutritional requirements of postimplantation rat embryos in culture.

21 January 2018

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Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol

21 January 2018

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Towards a cellular and molecular understanding of neurulation

21 January 2018

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Developmental basis of severe neural tube defects in the loop-tail (Lp) mutant mouse: use of microsatellite DNA markers to identify embryonic genotype.

21 January 2018

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The genetic basis of mammalian neurulation.

21 January 2018

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Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

21 January 2018

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Waardenburg I syndrome: a clinical and genetic study of two large Brazilian kindreds, and literature review

21 January 2018

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Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

FZD6is a novel gene for human neural tube defects

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Human neural tube defects: developmental biology, epidemiology, and genetics

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Segmental costovertebral malformations: association with neural tube defects. Report of 3 cases and review of the literature

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Parallel changes in metabolite and expression profiles in crooked-tail mutant and folate-reduced wild-type mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Maternal methionine supplementation promotes the remediation of axial defects in Axd mouse neural tube mutants

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Expression of a new mutation (Axd) causing axial defects in mice correlates with maternal phenotype and age.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Evidence that elevated glucose causes altered gene expression, apoptosis, and neural tube defects in a mouse model of diabetic pregnancy.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Embryonic folate metabolism and mouse neural tube defects

21 January 2018

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Notochord-dependent expression of MFH1 and PAX1 cooperates to maintain the proliferation of sclerotome cells during the vertebral column development

21 January 2018

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Maternal fumonisin exposure as a risk factor for neural tube defects

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Hyperglycemia-induced teratogenesis is mediated by a functional deficiency of arachidonic acid

21 January 2018

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Mechanistic insights into folate supplementation from Crooked tail and other NTD-prone mutant mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Inositol prevents folate-resistant neural tube defects in the mouse.

21 January 2018

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Mouse models of neural tube defects: investigating preventive mechanisms.

21 January 2018

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Development of the vertebrate central nervous system: formation of the neural tube.

21 January 2018

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Understanding the causes and prevention of neural tube defects: Insights from the splotch mouse model.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Genetics of human neural tube defects

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Maternal myo-inositol, glucose, and zinc status is associated with the risk of offspring with spina bifida

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Grainyhead genes and mammalian neural tube closure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Expression of the Axd (axial defects) mutation in the mouse is insensitive to retinoic acid at low dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Interaction between undulated and Patch leads to an extreme form of spina bifida in double-mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Grhl3 and Lmo4 play coordinate roles in epidermal migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

PAX genes and human neural tube defects: an amino acid substitution in PAX1 in a patient with spina bifida

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

A frameshift mutation in the gene for PAX3 in a girl with spina bifida and mild signs of Waardenburg syndrome

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Loss of Membrane Targeting of Vangl Proteins Causes Neural Tube Defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Altered regulation of platelet-derived growth factor receptor-alpha gene-transcription in vitro by spina bifida-associated mutant Pax1 proteins

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Novel mutations in VANGL1 in neural tube defects

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Toward understanding the genetic basis of neural tube defects.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Contribution of VANGL2 mutations to isolated neural tube defects

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Mutations in VANGL1 associated with neural-tube defects

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Strain-specific modifier genes ofCecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Identification and characterization of Grainyhead-like epithelial transactivator (GET-1), a novel mammalian Grainyhead-like factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Prenatal diagnosis and genetic counseling in a case of spina bifida in a family with Waardenburg syndrome type I

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Neurofibromin deficiency in mice causes exencephaly and is a modifier for Splotch neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

The LIM domain-only protein LMO4 is required for neural tube closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Hypoxic stress in diabetic pregnancy contributes to impaired embryo gene expression and defective development by inducing oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Impact of methylenetetrahydrofolate reductase deficiency and low dietary folate on the development of neural tube defects in splotch mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Expression of the gene encoding the high-Km glucose transporter 2 by the early postimplantation mouse embryo is essential for neural tube defects associated with diabetic embryopathy

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Homocysteine metabolism in pregnancies complicated by neural-tube defects

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Cooperative model of epithelial shaping and bending during avian neurulation: autonomous movements of the neural plate, autonomous movements of the epidermis, and interactions in the neural plate/epidermis transition zone.

21 January 2018

1 reference

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Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification

21 January 2018

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Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

21 January 2018

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A radiological study of vertebral and rib malformations in children with myelomeningocele

21 January 2018

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A rare case of anterior thoracic myelomeningocele with scoliosis--case report and review of the literature

21 January 2018

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Folic acid prevents congenital malformations in the offspring of diabetic mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis

21 January 2018

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Updated national birth prevalence estimates for selected birth defects in the United States, 2004-2006

21 January 2018

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Wnt signaling in caudal dysgenesis and diabetic embryopathy

21 January 2018

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Maternal diabetes alters transcriptional programs in the developing embryo

21 January 2018

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Spina bifida occulta in homozygous Patch mouse embryos.

21 January 2018

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Disruption of PDGFRalpha-initiated PI3K activation and migration of somite derivatives leads to spina bifida.

21 January 2018

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Review and update of mutations causing Waardenburg syndrome.

21 January 2018

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Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion

21 January 2018

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Dynamic imaging of mammalian neural tube closure

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Whole genomewide linkage screen for neural tube defects reveals regions of interest on chromosomes 7 and 10.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Characterization of differential gene expression profiles in diabetic embryopathy using DNA microarray analysis

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Regional neural tube closure defined by the Grainy head-like transcription factors

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates

21 January 2018

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The making of the somite: molecular events in vertebrate segmentation

21 January 2018

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Neural tube defect genes and maternal diabetes during pregnancy

21 January 2018

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Dick Smithells, folic acid, and the prevention of neural tube defects

21 January 2018

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The curly-tail mouse: an experimental model for human neural tube defects

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Molecular cytogenetic characterization of multiple intrachromosomal rearrangements of chromosome 2q in a patient with Waardenburg's syndrome and other congenital defects

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Regional differences in morphogenesis of the neuroepithelium suggest multiple mechanisms of spinal neurulation in the mouse

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21011

Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

High-density single nucleotide polymorphism screen in a large multiplex neural tube defect family refines linkage to loci at 7p21.1-pter and 2q33.1-q35.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Maternal hyperhomocysteinemia: a risk factor for neural-tube defects?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

A homolog of Drosophila grainy head is essential for epidermal integrity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Interaction of PDGFRA promoter haplotypes and maternal environmental exposures in the risk of spina bifida

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Genetic interaction between members of the Vangl family causes neural tube defects in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Genetic variation in genes of folate metabolism and neural-tube defect risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Curly tail: a 50-year history of the mouse spina bifida model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Neural tube closure requires Dishevelled-dependent convergent extension of the midline

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

PIP5KI gamma is required for cardiovascular and neuronal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

The effects of food shortage on human reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Importance of methyl donors during reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Modeling neural tube defects in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Refinement of 2q and 7p loci in a large multiplex NTD family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21011

21 January 2018

Identifiers

DOI

10.1002/BDRC.21011

1 reference

27 August 2017

1 reference