Role of FGFs/FGFRs in skeletal development and bone regeneration (Q37989404)

26 August 2017

title

Role of FGFs/FGFRs in skeletal development and bone regeneration (English)

1 reference

26 August 2017

Xiaolan Du

1

1 reference

26 August 2017

Yangli Xie

series ordinal

2

1 reference

26 August 2017

Cory J Xian

series ordinal

3

1 reference

26 August 2017

Lin Chen

series ordinal

4

1 reference

26 August 2017

publication date

1 December 2012

1 reference

Journal of Cellular Physiology

26 August 2017

published in

1 reference

26 August 2017

volume

227

1 reference

26 August 2017

issue

12

1 reference

26 August 2017

page(s)

3731-3743

1 reference

Fibroblast growth factor signaling uses multiple mechanisms to inhibit Wnt-induced transcription in osteoblasts.

26 August 2017

cites work

1 reference

A novel mutation in fibroblast growth factor 23 gene as a cause of tumoral calcinosis

21 January 2018

1 reference

Crouzon with acanthosis nigricans. Further delineation of the syndrome

21 January 2018

1 reference

An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia.

21 January 2018

1 reference

Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation.

21 January 2018

1 reference

Regulation of fracture repair by growth factors

21 January 2018

1 reference

Wnt pathway, an essential role in bone regeneration

21 January 2018

1 reference

Roles of FGF signaling in skeletal development and human genetic diseases

21 January 2018

1 reference

Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis

21 January 2018

1 reference

A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia

21 January 2018

1 reference

A Ser250Trp substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis

21 January 2018

1 reference

Effects of FGF-2 on metaphyseal fracture repair in rabbit tibiae

21 January 2018

1 reference

Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing

21 January 2018

1 reference

Sprouty proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development.

21 January 2018

1 reference

Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice

21 January 2018

1 reference

Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.

21 January 2018

1 reference

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

21 January 2018

1 reference

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference

21 January 2018

1 reference

Syndromic craniosynostosis: from history to hydrogen bonds

21 January 2018

1 reference

Mechanisms underlying differential responses to FGF signaling

21 January 2018

1 reference

Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias

21 January 2018

1 reference

Spatio-temporal expression of FGFR 1, 2 and 3 genes during human embryo-fetal ossification.

21 January 2018

1 reference

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

21 January 2018

1 reference

Mechanisms of bone repair and regeneration

21 January 2018

1 reference

Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome

21 January 2018

1 reference

Effects of FGF-2/-9 in calvarial bone cell cultures: differentiation stage-dependent mitogenic effect, inverse regulation of BMP-2 and noggin, and enhancement of osteogenic potential

21 January 2018

1 reference

Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.

21 January 2018

1 reference

Does adult fracture repair recapitulate embryonic skeletal formation?

21 January 2018

1 reference

Biological approaches to bone regeneration by gene therapy

21 January 2018

1 reference

Gene therapy approaches for bone regeneration

21 January 2018

1 reference

FGF23 is a hormone-regulating phosphate metabolism--unique biological characteristics of FGF23.

21 January 2018

1 reference

Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling.

21 January 2018

1 reference

Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice.

21 January 2018

1 reference

Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation.

21 January 2018

1 reference

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

21 January 2018

1 reference

FGF9 monomer-dimer equilibrium regulates extracellular matrix affinity and tissue diffusion

21 January 2018

1 reference

FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod

21 January 2018

1 reference

Impaired bone anabolic response to parathyroid hormone in Fgf2-/- and Fgf2+/- mice.

21 January 2018

1 reference

Fibroblast growth factors lead to increased Msx2 expression and fusion in calvarial sutures

21 January 2018

1 reference

Sequential treatment with basic fibroblast growth factor and PTH is more efficacious than treatment with PTH alone for increasing vertebral bone mass and strength in osteopenic ovariectomized rats

21 January 2018

1 reference

A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos.

21 January 2018

1 reference

Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation

21 January 2018

1 reference

Genetic and transcriptional control of bone formation

21 January 2018

1 reference

Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts

21 January 2018

1 reference

Acidic fibroblast growth factor (aFGF) injection stimulates cartilage enlargement and inhibits cartilage gene expression in rat fracture healing

21 January 2018

1 reference

Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia

21 January 2018

1 reference

Teriparatide (1-34 human PTH) regulation of osterix during fracture repair

21 January 2018

1 reference

Enhanced chondrogenesis and Wnt signaling in PTH-treated fractures

21 January 2018

1 reference

Reaching a genetic and molecular understanding of skeletal development

21 January 2018

1 reference

Genetic control of bone formation

21 January 2018

1 reference

Local application of recombinant human fibroblast growth factor-2 on bone repair: a dose-escalation prospective trial on patients with osteotomy

21 January 2018

1 reference

Modulation of signalling by Sprouty: a developing story

21 January 2018

1 reference

A local bone anabolic effect of rhFGF2-impregnated gelatin hydrogel by promoting cell proliferation and coordinating osteoblastic differentiation

21 January 2018

1 reference

Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasis

21 January 2018

1 reference

Developmental regulation of the growth plate

21 January 2018

1 reference

Anabolic effect of aminoterminally truncated fibroblast growth factor 4 (FGF4) on bone

21 January 2018

1 reference

Fibroblast growth factor expression in the postnatal growth plate

21 January 2018

1 reference

Increased osteoblast apoptosis in apert craniosynostosis: role of protein kinase C and interleukin-1.

21 January 2018

1 reference

A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors

21 January 2018

1 reference

FGFR3 down-regulates PTH/PTHrP receptor gene expression by mediating JAK/STAT signaling in chondrocytic cell line.

21 January 2018

1 reference

Basic fibroblast growth factor enhances in vitro mineralization of rat bone marrow stromal cells grown on non-woven hyaluronic acid based polymer scaffold

21 January 2018

1 reference

Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18

21 January 2018

1 reference

Increased expression of protein kinase Calpha, interleukin-1alpha, and RhoA guanosine 5'-triphosphatase in osteoblasts expressing the Ser252Trp fibroblast growth factor 2 receptor Apert mutation: identification by analysis of complementary DNA micro

21 January 2018

1 reference

Fgf-9 is required for angiogenesis and osteogenesis in long bone repair.

21 January 2018

1 reference

Fgf-18 Is Required for Osteogenesis But Not Angiogenesis During Long Bone Repair

21 January 2018

1 reference

Fibroblast growth factor receptor 1 regulates the differentiation and activation of osteoclasts through Erk1/2 pathway.

21 January 2018

1 reference

Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis

21 January 2018

1 reference

Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts

21 January 2018

1 reference

Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation

21 January 2018

1 reference

Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning

21 January 2018

1 reference

Fibroblast growth factor signaling controlling osteoblast differentiation

21 January 2018

1 reference

Review of the recently defined molecular mechanisms underlying thanatophoric dysplasia and their potential therapeutic implications for achondroplasia

21 January 2018

1 reference

Fibroblast growth factor receptor 3 (FGFR3) transmembrane mutation in Crouzon syndrome with acanthosis nigricans

21 January 2018

1 reference

LADD syndrome is caused by FGF10 mutations

21 January 2018

1 reference

Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation

21 January 2018

1 reference

Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation

21 January 2018

1 reference

Fgf8 is required for outgrowth and patterning of the limbs

21 January 2018

1 reference

Blocking endogenous FGF-2 activity prevents cranial osteogenesis.

21 January 2018

1 reference

Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis

21 January 2018

1 reference

Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway

21 January 2018

1 reference

Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype

21 January 2018

1 reference

Recombinant human basic fibroblast growth factor accelerates fracture healing by enhancing callus remodeling in experimental dog tibial fracture

21 January 2018

1 reference

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis

21 January 2018

1 reference

Heterozygous mutations in natriuretic peptide receptor-B (NPR2) are associated with short stature.

21 January 2018

1 reference

21 January 2018

1 reference

FGF signaling in the developing endochondral skeleton

21 January 2018

1 reference

Fibroblast growth factors

21 January 2018

1 reference

FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease

21 January 2018

1 reference

Complementary antagonistic actions between C-type natriuretic peptide and the MAPK pathway through FGFR-3 in ATDC5 cells

21 January 2018

1 reference

Expression of angiogenic factors during distraction osteogenesis

21 January 2018

1 reference

A skeleton in the closet: neogenin guides bone development

21 January 2018

1 reference

Molecular mechanisms of endochondral bone development.

21 January 2018

1 reference

Anabolic effects of basic fibroblast growth factor in the tibial diaphysis of ovariectomized rats

21 January 2018

1 reference

Novel formulation of fibroblast growth factor-2 in a hyaluronan gel accelerates fracture healing in nonhuman primates

21 January 2018

1 reference

Mutations in different components of FGF signaling in LADD syndrome

21 January 2018

1 reference

Clinical findings in a patient with FGFR1 P252R mutation and comparison with the literature.

21 January 2018

1 reference

Fibroblast growth factor expression during skeletal fracture healing in mice

21 January 2018

1 reference

Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

21 January 2018

1 reference

RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis

21 January 2018

1 reference

Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: double-blind, randomized, controlled clinical trial

21 January 2018

1 reference

Over-expression of fibroblast growth factor-2 causes defective bone mineralization and osteopenia in transgenic mice

21 January 2018

1 reference

Temporal expression of proteoglycans in the rat limb during bone healing.

21 January 2018

1 reference

FGF signaling: its role in bone development and human skeleton diseases

21 January 2018

1 reference

Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis

21 January 2018

1 reference

Effect of FGF-2 and melatonin on implant bone healing: a histomorphometric study

21 January 2018

1 reference

Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3.

21 January 2018

1 reference

Bone morphogenetic proteins and bFGF exert opposing regulatory effects on PTHrP expression and inorganic pyrophosphate elaboration in immortalized murine endochondral hypertrophic chondrocytes (MCT cells).

21 January 2018

1 reference

Sef is a spatial regulator for Ras/MAP kinase signaling

21 January 2018

1 reference

Regulatory mechanisms and function of ERK MAP kinases

21 January 2018

1 reference

A novel mutation in FGFR3 causes camptodactyly, tall stature, and hearing loss (CATSHL) syndrome

21 January 2018

1 reference

Promotion and attenuation of FGF signaling through the Ras-MAPK pathway

21 January 2018

1 reference

Identification of Sef, a novel modulator of FGF signalling

21 January 2018

1 reference

PTH has the potential to rescue disturbed bone growth in achondroplasia

21 January 2018

1 reference

Defective bone mineralization and osteopenia in young adult FGFR3-/- mice

21 January 2018

1 reference

Recapitulation of signals regulating embryonic bone formation during postnatal growth and in fracture repair.

21 January 2018

1 reference

Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse

21 January 2018

1 reference

Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation

21 January 2018

1 reference

A recurrent mutation, ala391glu, in the transmembrane region of FGFR3 causes Crouzon syndrome and acanthosis nigricans

21 January 2018

1 reference

Multiple synostoses syndrome is due to a missense mutation in exon 2 of FGF9 gene

21 January 2018

1 reference

Stat1 controls postnatal bone formation by regulating fibroblast growth factor signaling in osteoblasts

21 January 2018

1 reference

hSef inhibits PC-12 cell differentiation by interfering with Ras-mitogen-activated protein kinase MAPK signaling.

21 January 2018

1 reference

Fibroblast growth factor receptors (FGFRs) and their roles in limb development

21 January 2018

1 reference

Translational research of C-type natriuretic peptide (CNP) into skeletal dysplasias

21 January 2018

1 reference

A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis

21 January 2018

1 reference

Mineralized tissue cells are a principal source of FGF23.

21 January 2018

1 reference

FGF23 and disorders of phosphate homeostasis

21 January 2018

1 reference

Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth

21 January 2018

1 reference

Spatial and temporal gene expression for fibroblast growth factor type I receptor (FGFR1) during fracture healing in the rat

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCP.24083

1 reference

26 August 2017

1 reference