Therapeutic targeting of the complement system in age-related macular degeneration: a review. (Q37981256)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22304025%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Therapeutic targeting of the complement system in age-related macular degeneration: a review (English)

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22 January 2020

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3

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22 January 2020

author name string

Robyn Troutbeck

series ordinal

1

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22 January 2020

Salmaan Al-Qureshi

series ordinal

2

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22 January 2020

publication date

1 January 2012

1 reference

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Clinical and Experimental Ophthalmology

22 January 2020

published in

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22 January 2020

volume

40

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22 January 2020

issue

1

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22 January 2020

page(s)

18-26

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A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

22 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Complement factor H polymorphism in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Complement factor H polymorphism and age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Complement factor H variant increases the risk of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

The role of complement in inflammatory diseases from behind the scenes into the spotlight

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

The role of complement in the development of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

A role for local inflammation in the formation of drusen in the aging eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Early stages of age-related macular degeneration: an immunofluorescence and electron microscopy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Structure and composition of drusen associated with glomerulonephritis: implications for the role of complement activation in drusen biogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Complement C3 variant and the risk of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

The human complement factor H: functional roles, genetic variations and disease associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

The role of complement system in ocular diseases including uveitis and macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

C-reactive protein levels and complement factor H polymorphism interaction in age-related macular degeneration and its progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Ranibizumab versus verteporfin for neovascular age-related macular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Ranibizumab for neovascular age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

A phase I trial of an IV-administered vascular endothelial growth factor trap for treatment in patients with choroidal neovascularization due to age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Predicted biological activity of intravitreal VEGF Trap.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Progress and perspectives on the role of RPE cell inflammatory responses in the development of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Antiangiogenic approaches to age-related macular degeneration in the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Current molecular understanding and future treatment strategies for pathologic ocular neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Emerging pharmacologic therapies for wet age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Therapeutic antibodies for human diseases at the dawn of the twenty-first century

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Targeting C5a: recent advances in drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Peptidomimetic C5a receptor antagonists with hydrophobic substitutions at the C-terminus: increased receptor specificity and in vivo activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Structure and function of C1-inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Localization of complement 1 inhibitor (C1INH/SERPING1) in human eyes with age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

The SERPING1 gene and age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Decay Accelerating Factor (CD55)–Mediated Attenuation of Complement: Therapeutic Implications for Age-Related Macular Degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Chlamydia pneumoniae and age-related macular degeneration: a role in pathogenesis or merely a chance association?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Gene-environment interaction in progression of AMD: the CFH gene, smoking and exposure to chronic infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

Choroidal neovascularization enhanced by Chlamydia pneumoniae via Toll-like receptor 2 in the retinal pigment epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1442-9071.2011.02581.X

10.1111/J.1442-9071.2011.02581.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22304025%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

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