Endoplasmic reticulum stress and the ER mitochondrial calcium cycle in amyotrophic lateral sclerosis (Q37980249)

26 August 2017

title

Endoplasmic reticulum stress and the ER mitochondrial calcium cycle in amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

26 August 2017

main subject

endoplasmic reticulum

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3

Julian Grosskreutz

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26 August 2017

author name string

Janin Lautenschlaeger

series ordinal

1

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26 August 2017

Tino Prell

series ordinal

2

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26 August 2017

publication date

1 February 2012

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Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders

26 August 2017

published in

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26 August 2017

volume

13

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26 August 2017

issue

2

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26 August 2017

page(s)

166-177

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

26 August 2017

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The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease

21 January 2018

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21 January 2018

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

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21 January 2018

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Endoplasmic reticulum stress response and neurodegeneration

21 January 2018

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

21 January 2018

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Structure and intermolecular interactions of the luminal dimerization domain of human IRE1alpha

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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

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21 January 2018

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

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21 January 2018

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ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

21 January 2018

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Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP

21 January 2018

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The mammalian unfolded protein response

21 January 2018

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Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

A structural overview of the PDI family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis

21 January 2018

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https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 January 2018

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https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Tripartite management of unfolded proteins in the endoplasmic reticulum

21 January 2018

1 reference

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Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance

21 January 2018

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21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Altered distribution and levels of cathepsinD and cystatins in amyotrophic lateral sclerosis transgenic mice: possible roles in motor neuron survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Another way to die: autophagic programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Endoplasmic reticulum, Bcl-2 and Ca2+ handling in apoptosis

21 January 2018

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https://api.crossref.org/works/10.3109%2F17482968.2011.641569

ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

The molecular links between TDP-43 dysfunction and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Progressive motor weakness in transgenic mice expressing human TDP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Anterior horn cells with abnormal TDP-43 immunoreactivities show fragmentation of the Golgi apparatus in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Characterization of the Properties of a Novel Mutation in VAPB in Familial Amyotrophic Lateral Sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

VAPB interacts with and modulates the activity of ATF6.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

Role of mitochondria in kainate-induced fast Ca2+ transients in cultured spinal motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17482968.2011.641569

10.3109/17482968.2011.641569

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference