The role of RNA in mammalian prion protein conversion (Q37957794)

25 August 2017

title

The role of RNA in mammalian prion protein conversion (English)

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25 August 2017

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Mariana P B Gomes

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Tuane C R G Vieira

series ordinal

2

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25 August 2017

publication date

17 November 2011

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Wiley interdisciplinary reviews. RNA

25 August 2017

published in

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25 August 2017

volume

3

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issue

3

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25 August 2017

page(s)

415-428

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Mammalian prion biology: one century of evolving concepts

25 August 2017

cites work

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Self-replication and scrapie

21 January 2018

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21 January 2018

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Novel proteinaceous infectious particles cause scrapie

21 January 2018

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The exceptionally small size of the scrapie agent

21 January 2018

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RESISTANCE OF THE SCRAPIE AGENT TO FORMALIN.

21 January 2018

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Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 January 2018

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Mice devoid of PrP are resistant to scrapie

21 January 2018

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A cellular gene encodes scrapie PrP 27-30 protein

21 January 2018

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Intriguing nucleic-acid-binding features of mammalian prion protein

21 January 2018

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Structural insights into the interaction between prion protein and nucleic acid

21 January 2018

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DNA converts cellular prion protein into the beta-sheet conformation and inhibits prion peptide aggregation

21 January 2018

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Formation of native prions from minimal components in vitro

21 January 2018

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Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion

21 January 2018

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Cellular isoform of the scrapie agent protein participates in lymphocyte activation

21 January 2018

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Scrapie prion protein contains a phosphatidylinositol glycolipid

21 January 2018

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Glycosylation differences between the normal and pathogenic prion protein isoforms

21 January 2018

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Prion glycoprotein: structure, dynamics, and roles for the sugars

21 January 2018

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Copper binding to the prion protein: structural implications of four identical cooperative binding sites

21 January 2018

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The cellular prion protein binds copper in vivo

21 January 2018

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NMR structure of the mouse prion protein domain PrP(121-231)

21 January 2018

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NMR characterization of the full‐length recombinant murine prion protein, mPrP(23–231)

21 January 2018

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MOLMOL: a program for display and analysis of macromolecular structures

21 January 2018

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DISPLAR: an accurate method for predicting DNA-binding sites on protein surfaces

21 January 2018

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Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

21 January 2018

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The α-helical C-terminal domain of full-length recombinant PrP converts to an in-register parallel β-sheet structure in PrP fibrils: evidence from solid state nuclear magnetic resonance

21 January 2018

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Scrapie prions: a three-dimensional model of an infectious fragment

21 January 2018

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Evidence for assembly of prions with left-handed beta-helices into trimers

21 January 2018

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Folding of prion protein to its native alpha-helical conformation is under kinetic control

21 January 2018

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Pathologic conformations of prion proteins

21 January 2018

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Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier

21 January 2018

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Cell-free formation of protease-resistant prion protein.

21 January 2018

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21 January 2018

The state of the prion

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RNA molecules stimulate prion protein conversion

21 January 2018

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Scrapie-associated PrP accumulation and its inhibition: revisiting the amyloid-glycosaminoglycan connection

21 January 2018

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Biochemistry and structure of PrPC and PrPSc

21 January 2018

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Globular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversion

21 January 2018

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Physiology of the prion protein

21 January 2018

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Cellular prion protein: on the road for functions

21 January 2018

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Cellular prion protein binds laminin and mediates neuritogenesis

21 January 2018

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Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection

21 January 2018

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Reciprocal remodeling upon binding of the prion protein to its signaling partner hop/STI1.

21 January 2018

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Attempts to restore scrapie prion infectivity after exposure to protein denaturants

21 January 2018

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Protease-resistant prion protein produced in vitro lacks detectable infectivity.

21 January 2018

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Protease-resistant and detergent-insoluble prion protein is not necessarily associated with prion infectivity

21 January 2018

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Polymerization of murine recombinant prion protein in nucleic acid solution

21 January 2018

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Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding

21 January 2018

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In vitro amplification of protease-resistant prion protein requires free sulfhydryl groups

21 January 2018

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Generating a prion with bacterially expressed recombinant prion protein

21 January 2018

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Prion diseases: a nucleic-acid accomplice?

21 January 2018

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Pathway complexity of prion protein assembly into amyloid

21 January 2018

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The hypothesis of the catalytic action of nucleic acid on the conversion of prion protein

21 January 2018

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Heparan sulfate is a cellular receptor for purified infectious prions.

21 January 2018

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Prion diseases and neurodegeneration

21 January 2018

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Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22

21 January 2018

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Non-coding RNAs: new players in eukaryotic biology

21 January 2018

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RNAs as extracellular signaling molecules

21 January 2018

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Birth, life and death of nascent polypeptide chains.

21 January 2018

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The various facets of the protein-folding activity of the ribosome

21 January 2018

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Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs

21 January 2018

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The relationship between non-protein-coding DNA and eukaryotic complexity

21 January 2018

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Non-coding RNAs: regulators of disease

21 January 2018

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RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans

21 January 2018

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Specific interference by ingested dsRNA

21 January 2018

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

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Non-coding RNAs: lost in translation?

21 January 2018

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Cell-specific RNA-binding proteins in human disease

21 January 2018

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Diverse RNA-binding proteins interact with functionally related sets of RNAs, suggesting an extensive regulatory system

21 January 2018

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BC200 RNA in normal human neocortex, non-Alzheimer dementia (NAD), and senile dementia of the Alzheimer type (AD).

21 January 2018

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In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs.

21 January 2018

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Small, highly structured RNAs participate in the conversion of human recombinant PrP(Sen) to PrP(Res) in vitro

21 January 2018

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Nucleic acid and prion protein interaction produces spherical amyloids which can function in vivo as coats of spongiform encephalopathy agent

21 January 2018

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Prion protein conversion in vitro

21 January 2018

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The peculiar interaction between mammalian prion protein and RNA

21 January 2018

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A protease-resistant protein is a structural component of the scrapie prion

21 January 2018

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Molecular characteristics of the major scrapie prion protein

21 January 2018

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Purification and structural studies of a major scrapie prion protein

21 January 2018

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Prion protein complexed to N2a cellular RNAs through its N-terminal domain forms aggregates and is toxic to murine neuroblastoma cells

21 January 2018

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Selective incorporation of polyanionic molecules into hamster prions

21 January 2018

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Interaction of prion peptide HuPrP106-126 with nucleic acid

21 January 2018

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Characterization of 2'-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion.

21 January 2018

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Structural determinants of conformationally selective, prion-binding aptamers.

21 January 2018

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Potent antiscrapie activities of degenerate phosphorothioate oligonucleotides

21 January 2018

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Species-dependent differences in cofactor utilization for formation of the protease-resistant prion protein in vitro

21 January 2018

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Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions

21 January 2018

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DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid

21 January 2018

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Amplification of purified prions in vitro

21 January 2018

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In Situ Photodegradation of Incorporated Polyanion Does Not Alter Prion Infectivity

21 January 2018

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Cellular heparan sulfate participates in the metabolism of prions

21 January 2018

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Matrix proteoglycans: from molecular design to cellular function

21 January 2018

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Glycomics approach to structure-function relationships of glycosaminoglycans

21 January 2018

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Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein

21 January 2018

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Inhibition of scrapie-associated PrP accumulation. Probing the role of glycosaminoglycans in amyloidogenesis

21 January 2018

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Cryo-immunogold electron microscopy for prions: toward identification of a conversion site

21 January 2018

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The abnormal isoform of the prion protein accumulates in late-endosome-like organelles in scrapie-infected mouse brain

21 January 2018

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Identification of an intracellular site of prion conversion

21 January 2018

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The mechanism of internalization of glycosylphosphatidylinositol-anchored prion protein

21 January 2018

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The highways and byways of prion protein trafficking

21 January 2018

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Copper-dependent co-internalization of the prion protein and glypican-1.

21 January 2018

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Sulphate polyanions prolong the incubation period of scrapie-infected hamsters.

21 January 2018

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Structure-activity studies of heparan mimetic polyanions for anti-prion therapies

21 January 2018

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Electrostatic effects in proteins

21 January 2018

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Identification and analysis of long-range electrostatic effects in proteins by computer modeling:aspartate transcarbamylase.

21 January 2018

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Do salt bridges stabilize proteins? A continuum electrostatic analysis.

21 January 2018

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Fine mapping of the sequences in domain 5 of high molecular weight kininogen (HK) interacting with heparin and zinc

21 January 2018

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Common physical basis of macromolecule-binding sites in proteins

21 January 2018

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Identification of the heparan sulfate binding sites in the cellular prion protein

21 January 2018

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Glycosaminoglycans as polyelectrolytes

21 January 2018

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Thioaptamer interactions with prion proteins: sequence-specific and non-specific binding sites

21 January 2018

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Characterization and application of a novel RNA aptamer against the mouse prion protein

21 January 2018

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Disordered RNA chaperone proteins: from functions to disease

21 January 2018

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The prion protein has RNA binding and chaperoning properties characteristic of nucleocapsid protein NCP7 of HIV-1.

21 January 2018

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Molecular basis for target RNA recognition and cleavage by human RISC.

21 January 2018

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The ubiquitous nature of RNA chaperone proteins

21 January 2018

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Assaying RNA chaperone activity in vivo using a novel RNA folding trap

21 January 2018

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PrPC has nucleic acid chaperoning properties similar to the nucleocapsid protein of HIV-1.

21 January 2018

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Functional interactions of nucleocapsid protein of feline immunodeficiency virus and cellular prion protein with the viral RNA.

21 January 2018

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Bending and unwinding of nucleic acid by prion protein

21 January 2018

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A large ribonucleoprotein particle induced by cytoplasmic PrP shares striking similarities with the chromatoid body, an RNA granule predicted to function in posttranscriptional gene regulation

21 January 2018

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The role of structural disorder in the function of RNA and protein chaperones

21 January 2018

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A neuronal isoform of the aplysia CPEB has prion-like properties

21 January 2018

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Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation.

21 January 2018

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Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions

21 January 2018

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Isolation of drugs active against mammalian prions using a yeast-based screening assay

21 January 2018

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A yeast-based assay to isolate drugs active against mammalian prions

21 January 2018

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A novel generation of heparan sulfate mimetics for the treatment of prion diseases

21 January 2018

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Spontaneous generation of mammalian prions

21 January 2018

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Cognate DNA stabilizes the tumor suppressor p53 and prevents misfolding and aggregation.

21 January 2018

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Fibrillar aggregates of the tumor suppressor p53 core domain

21 January 2018

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Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins

21 January 2018

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Protein-DNA Interaction at the Origin of Neurological Diseases: A Hypothesis

21 January 2018

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Defined DNA sequences promote the assembly of a bacterial protein into distinct amyloid nanostructures

21 January 2018

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Electrostatic interactions in macromolecules: theory and applications

21 January 2018

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Heparin Binding by Murine Recombinant Prion Protein Leads to Transient Aggregation and Formation of RNA-Resistant Species

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/WRNA.118

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25 August 2017

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