Kynurenines in Parkinson's disease: therapeutic perspectives. (Q37920750)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858430%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

review article

1 reference

title

Kynurenines in Parkinson's disease: therapeutic perspectives (English)

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11 February 2020

1 reference

2

1 reference

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11 February 2020

Laszlo Vecsei

series ordinal

5

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11 February 2020

3

József Toldi

1 reference

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11 February 2020

1

Dénes Zádori

1 reference

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11 February 2020

4

Ferenc Fülöp

1 reference

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11 February 2020

publication date

20 August 2011

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Journal of Neural Transmission

11 February 2020

published in

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11 February 2020

volume

119

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11 February 2020

issue

2

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11 February 2020

page(s)

275-283

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DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

11 February 2020

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21 January 2018

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Syntheses, transformations and pharmaceutical applications of kynurenic acid derivatives

21 January 2018

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A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1.

21 January 2018

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Synthesis and metabolism of L-kynurenine in rat brain

21 January 2018

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21 January 2018

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21 January 2018

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Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys

21 January 2018

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21 January 2018

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21 January 2018

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Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

21 January 2018

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Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

21 January 2018

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Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease

21 January 2018

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Specificity of dopaminergic neuronal degeneration induced by intracerebral injection of 6-hydroxydopamine in the nigrostriatal dopamine system

21 January 2018

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A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists

21 January 2018

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PINK1 controls mitochondrial localization of Parkin through direct phosphorylation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat

21 January 2018

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Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

21 January 2018

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Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease

21 January 2018

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21 January 2018

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Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid

21 January 2018

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Innervation of the substantia nigra

21 January 2018

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Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain

21 January 2018

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Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

21 January 2018

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Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2.

21 January 2018

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Inflammatory process in Parkinson's disease: role for cytokines

21 January 2018

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Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

21 January 2018

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Kynurenine pathway abnormalities in Parkinson's disease

21 January 2018

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Two kynurenine aminotransferases in human brain

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Mapping of a gene for Parkinson's disease to chromosome 4q21-q23

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Endogenous kynurenines as targets for drug discovery and development

21 January 2018

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21 January 2018

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Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

21 January 2018

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Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35

21 January 2018

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Downregulation of parkin damages antioxidant defenses and enhances proteasome inhibition-induced toxicity in PC12 cells

21 January 2018

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Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family.

21 January 2018

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Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies

21 January 2018

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Endogenous neuroprotection in chronic neurodegenerative disorders: with particular regard to the kynurenines

21 January 2018

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Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington's disease.

21 January 2018

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Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

21 January 2018

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A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor

21 January 2018

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Activated human microglia produce the excitotoxin quinolinic acid

21 January 2018

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12 December 2020

The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

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Subthalamic nucleus-mediated excitotoxicity in Parkinson's disease: a target for neuroprotection.

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12 December 2020

Kynurenines, Parkinson's disease and other neurodegenerative disorders: preclinical and clinical studies.

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An update on the potential role of excitotoxicity in the pathogenesis of Parkinson's disease

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12 December 2020

3-Hydroxyanthranilic acid accumulation following administration of the 3-hydroxyanthranilic acid 3,4-dioxygenase inhibitor NCR-631

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12 December 2020

Neurotoxicity of the meperidine analogue N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on brain catecholamine neurons in the mouse

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12 December 2020

Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27

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12 December 2020

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12 December 2020

Effect of 7-chloro kynurenic acid on glycine modulation of the N-methyl-D-aspartate response in guinea-pig myenteric plexus

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12 December 2020

Parkinson's disease in a chemist working with 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

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12 December 2020

3‐Hydroxykynurenine, an Endogenous Oxidative Stress Generator, Causes Neuronal Cell Death with Apoptotic Features and Region Selectivity

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12 December 2020

In situ produced 7-chlorokynurenate provides protection against quinolinate- and malonate-induced neurotoxicity in the rat striatum

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12 December 2020

Protective effect of l-kynurenine and probenecid on 6-hydroxydopamine-induced striatal toxicity in rats: Implications of modulating kynurenate as a protective strategy

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12 December 2020

Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease.

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12 December 2020

Melatonin counteracts lipopolysaccharide-induced expression and activity of mitochondrial nitric oxide synthase in rats

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12 December 2020

Neuropharmacology of quinolinic and kynurenic acids

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12 December 2020

The effect of hormones and vitamin B6 on urinary excretion of metabolites of the kynurenine pathway

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12 December 2020

Time-course of kynurenic acid concentration in mouse serum following the administration of a novel kynurenic acid analog

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12 December 2020

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12 December 2020

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.

1 reference

12 December 2020

1 reference

12 December 2020

Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

1 reference

12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

12 December 2020

Different inhibitory effects of kynurenic acid and a novel kynurenic acid analogue on tumour necrosis factor-α (TNF-α) production by mononuclear cells, HMGB1 production by monocytes and HNP1-3 secretion by neutrophils

1 reference

12 December 2020

Systemic administration of 4-chlorokynurenine prevents quinolinate neurotoxicity in the rat hippocampus

1 reference

12 December 2020

Prevalence of Parkinson's disease in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group

1 reference

12 December 2020

Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists

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12 December 2020

1 reference

12 December 2020

10.1007/S00702-011-0697-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858430%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference