Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not? (Q37883011)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

review article

1 reference

title

Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

main subject

hypoxia

0 references

angiogenesis inhibitor

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Massimiliano Mazzone

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

3

Peter Carmeliet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

language of work or name

English

0 references

publication date

31 May 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Clinical Oncology

2 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

page(s)

393-404

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629216%20AND%20SRC:MED&resulttype=core&format=json

VEGF inhibition: insights from preclinical and clinical studies

2 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Regulation of angiogenesis by oxygen and metabolism.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Differential effects of the vascular endothelial growth factor receptor inhibitor PTK787/ZK222584 on tumor angiogenesis and tumor lymphangiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Metastasis: from dissemination to organ-specific colonization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

HIF-1: upstream and downstream of cancer metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Cancer dissemination--lessons from leukocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Collective cell migration in morphogenesis, regeneration and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Microenvironmental regulation of metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Mechanisms of motility in metastasizing cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Epithelial-mesenchymal transitions in development and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Tube travel: the role of proteases in individual and collective cancer cell invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Oxygen regulates epithelial-to-mesenchymal transition: insights into molecular mechanisms and relevance to disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia and hypoxia-inducible factors: master regulators of metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

31 March 2020

Hypoxia and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Lysyl oxidase mediates hypoxic control of metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

PTEN suppression of YY1 induces HIF-2 activity in von-Hippel-Lindau-null renal-cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Macrophage diversity enhances tumor progression and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The role of the organ microenvironment in brain metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

VEGF-A and the induction of pathological angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Tumor-induced endothelial cell apoptosis: roles of NAD(P)H oxidase-derived reactive oxygen species

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Endothelial-mural cell signaling in vascular development and angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia-inducible factor 1alpha mediates anoikis resistance via suppression of alpha5 integrin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Malignant cells facilitate lung metastasis by bringing their own soil

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Src family kinases as mediators of endothelial permeability: effects on inflammation and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia upregulates the synthesis of TGF-beta 1 by human dermal fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Tumor self-seeding by circulating cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The role of metastasis suppressor genes in metastatic dormancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Models, mechanisms and clinical evidence for cancer dormancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Tumor dormancy and metastasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Real-time imaging reveals the single steps of brain metastasis formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The angiogenic switch: implications in the regulation of tumor dormancy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Anti-placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia increases placenta growth factor expression in human myocardium and cultured neonatal rat cardiomyocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Bone morphogenetic protein 4 is induced in hepatocellular carcinoma by hypoxia and promotes tumour progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Modes of resistance to anti-angiogenic therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Regression of established tumors and metastases by potent vascular endothelial growth factor blockade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Anti-tumor effect of CT-322 as an adnectin inhibitor of vascular endothelial growth factor receptor-2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Effects of anti-VEGF treatment duration on tumor growth, tumor regrowth, and treatment efficacy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Anti-VEGF-A therapy reduces lymphatic vessel density and expression of VEGFR-3 in an orthotopic breast tumor model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Disease course patterns after discontinuation of bevacizumab: pooled analysis of randomized phase III trials

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Bevacizumab in metastatic breast cancer: a meta-analysis of randomized controlled trials.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Targeting angiogenesis driven by vascular endothelial growth factors using antibody-based therapies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Phase III Trial Assessing Bevacizumab in Stages II and III Carcinoma of the Colon: Results of NSABP Protocol C-08

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Rapid vascular regrowth in tumors after reversal of VEGF inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Antiangiogenic therapies for high-grade glioma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The hypoxic response of tumors is dependent on their microenvironment.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Glioblastoma stem-like cells give rise to tumour endothelium.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Transdifferentiation of glioblastoma cells into vascular endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Heterogeneity of the tumor vasculature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Pericytes: gatekeepers in tumour cell metastasis?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or docetaxel in a transgenic mouse model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Kinases as upstream regulators of the HIF system: their emerging potential as anti-cancer drug targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia inducible factor-2alpha: a critical mediator of aggressive tumor phenotypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hungry for blood vessels: linking metabolism and angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The role of HIF prolyl hydroxylases in tumour growth.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia and hepatocellular carcinoma: The therapeutic target for hepatocellular carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The Tumor Microenvironment and DNA Repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia helps glioma to fight therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia inducible factors in cancer stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Tie2-expressing monocytes and tumor angiogenesis: regulation by hypoxia and angiopoietin-2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia: A Link between Fibrogenesis, Angiogenesis, and Carcinogenesis in Liver Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Glioblastoma, cancer stem cells and hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

A perivascular niche for brain tumor stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via an autocrine loop.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

New evidence for tumour embolism as a mode of metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Metastasis in Melanoma Xenografts Is Associated with Tumor Microvascular Density Rather than Extent of Hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Evaluation of vascular endothelial growth factor blockade and matrix metalloproteinase inhibition as a combination therapy for experimental human pancreatic cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

PlGF blockade does not inhibit angiogenesis during primary tumor growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Anti-tumor and anti-metastatic effects of human-vascular-endothelial-growth-factor-neutralizing antibody on human colon and gastric carcinoma xenotransplanted orthotopically into nude mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Suppression of tumor growth and metastasis by simultaneously blocking vascular endothelial growth factor (VEGF)-A and VEGF-C with a receptor-immunoglobulin fusion protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Bevacizumab suppression of establishment of micrometastases in experimental ocular melanoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Suppressive effect of bevacizumab on peritoneal dissemination from gastric cancer in a peritoneal metastasis model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Effect of bevacizumab, a humanized monoclonal antibody to vascular endothelial growth factor, on peritoneal metastasis of MNK-45P human gastric cancer in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Cediranib/AZD2171 Inhibits Bone and Brain Metastasis in a Preclinical Model of Advanced Prostate Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Dual targeting of Raf and VEGF receptor 2 reduces growth and metastasis of pancreatic cancer through direct effects on tumor cells, endothelial cells, and pericytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Vascular endothelial growth factor trap combined with paclitaxel strikingly inhibits tumor and ascites, prolonging survival in a human ovarian cancer model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Combination therapy of interleukin-2 and sorafenib improves survival benefits and prevents spontaneous pulmonary metastasis in murine renal cell carcinoma models

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Suppression of primary tumor growth in a mouse model of human neuroblastoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

Sunitinib prolongs survival in genetically engineered mouse models of multistep lung carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.83

The HIF-2α-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization

31 March 2020

1 reference

12 December 2020

Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth.

1 reference

12 December 2020

Inhibition of tumor growth and metastasis by an immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permeability factor121

1 reference

12 December 2020

Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia

1 reference

12 December 2020

Tumor-vascular interactions and tumor dormancy

1 reference

12 December 2020

Efficacy of the combined use of bevacizumab and irinotecan as a postoperative adjuvant chemotherapy in colon carcinoma.

1 reference

12 December 2020

Anti-vascular endothelial growth factor receptor 2 antibody reduces tumorigenicity and metastasis in orthotopic prostate cancer xenografts via induction of endothelial cell apoptosis and reduction of endothelial cell matrix metalloproteinase type 9

1 reference

12 December 2020

Hypoxia induces PTHrP gene transcription in human cancer cells through the HIF-2α.

1 reference

12 December 2020

Neutralizing anti-vascular endothelial growth factor antibody inhibits further growth of established prostate cancer and metastases in a pre-clinical model

1 reference

12 December 2020

Signalling pathways in vasculogenic mimicry

1 reference

12 December 2020

Hypoxia and metastasis in breast cancer

1 reference

12 December 2020

Oxygen sensing: a common crossroad in cancer and neurodegeneration

1 reference

12 December 2020

Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis

1 reference

12 December 2020