Candidate genes and potential targets for therapeutics in Wilms’ tumour (Q37790163)

23 August 2017

title

Candidate genes and potential targets for therapeutics in Wilms' tumour (English)

1 reference

23 August 2017

Candidate genes and potential targets for therapeutics in Wilms’ tumour (English)

1 reference

https://api.crossref.org/works/10.1007/S12094-010-0564-Y

16 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20851800

16 July 2024

2

0 references

Christopher Blackmore

series ordinal

1

object named as

Christopher Blackmore

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20851800

16 July 2024

author name string

Aru Narendran

series ordinal

3

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23 August 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20851800

16 July 2024

publication date

1 September 2010

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full work available at URL

23 August 2017

http://link.springer.com/content/pdf/10.1007/s12094-010-0564-y.pdf

1 reference

https://api.crossref.org/works/10.1007/S12094-010-0564-Y

http://link.springer.com/article/10.1007/s12094-010-0564-y/fulltext.html

16 July 2024

1 reference

https://api.crossref.org/works/10.1007/S12094-010-0564-Y

http://link.springer.com/content/pdf/10.1007/s12094-010-0564-y

16 July 2024

1 reference

https://api.crossref.org/works/10.1007/S12094-010-0564-Y

Clinical and Translational Oncology

16 July 2024

published in

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23 August 2017

volume

12

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23 August 2017

issue

9

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23 August 2017

page(s)

597-605

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The genetics of Wilms' tumor--a case of disrupted development

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12094-010-0564-Y

Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-010-0564-Y

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-010-0564-Y

Toward an etiological classification of developmental disorders of the kidney and upper urinary tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-010-0564-Y

CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-010-0564-Y

Mapping of target regions of allelic loss in primary breast cancers to 1-cM intervals on genomic contigs at 6q21 and 6q25.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-010-0564-Y

Allelic imbalance of chromosome 6q in ovarian tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-010-0564-Y

Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-010-0564-Y

Gain of 1q is associated with adverse outcome in favorable histology Wilms' tumors

21 January 2018

1 reference

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Childhood cancer incidence: Geographical and temporal variations

21 January 2018

1 reference

12 December 2020

Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5.

1 reference

12 December 2020

Transcriptional regulation by WT1 in development.

1 reference

12 December 2020

A review of the phenotypic variation due to the Denys-Drash syndrome-associated germline WT1 mutation R362X

1 reference

12 December 2020

The Hedgehog and Wnt signalling pathways in cancer

1 reference

12 December 2020

Wilms' tumor 1-KTS isoforms induce p53-independent apoptosis that can be partially rescued by expression of the epidermal growth factor receptor or the insulin receptor.

1 reference

12 December 2020

Relaxation of imprinted genes in human cancer.

1 reference

12 December 2020

Maternal allele loss in Wilms' tumour

1 reference

12 December 2020

Familial Wilms' tumor: a descriptive study

1 reference

12 December 2020

Mechanisms of Wnt signaling in development

1 reference

12 December 2020

Tumor-specific loss of 11p15.5 alleles in del11p13 Wilms tumor and in familial adrenocortical carcinoma

1 reference

12 December 2020

Caught up in a Wnt storm: Wnt signaling in cancer

1 reference

12 December 2020

Prognostic classification of relapsing favorable histology Wilms tumor using cDNA microarray expression profiling and support vector machines

1 reference

12 December 2020

Non-chromosome 11-p syndromes in Wilms tumor patients: Clinical and cytogenetic report of two Down syndrome cases and one Turner syndrome case

1 reference

12 December 2020

Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress

1 reference

12 December 2020

WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries?

1 reference

12 December 2020

Identification of c-MYC as a target of the APC pathway

1 reference

12 December 2020

Constitutional translocation breakpoint mapping by genome-wide paired-end sequencing identifies HACE1 as a putative Wilms tumour susceptibility gene

1 reference

12 December 2020

WT1 expression alters tumorigenicity of the G401 kidney-derived cell line

1 reference

12 December 2020

The Wilms tumour gene, WT1, in normal and abnormal nephrogenesis

1 reference

12 December 2020

Nuclear accumulation of beta-catenin protein in Wilms' tumours

1 reference

12 December 2020

Fine structure analysis of the WT1 gene in sporadic Wilms tumors

1 reference

12 December 2020

X-inactivation profile reveals extensive variability in X-linked gene expression in females

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12 December 2020

Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus

1 reference

12 December 2020

TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels.

1 reference

12 December 2020

Expression of cyclooxygenase-2 in Wilms tumor: immunohistochemical study using tissue microarray methodology

1 reference

12 December 2020

Constitutional relaxation of insulin-like growth factor II gene imprinting associated with Wilms' tumour and gigantism

1 reference

12 December 2020

The prognostic significance of apoptosis-associated proteins BCL-2, BAX and BCL-X in clinical nephroblastoma

1 reference

12 December 2020

Mapping of a Putative Tumor Suppressor Locus to Proximal 7p in Wilms Tumors

1 reference

12 December 2020

Significance of proto-oncogene Bcl-X(S/L) expression in Wilms tumor

1 reference

12 December 2020

WT-1 is required for early kidney development

1 reference

12 December 2020

Association of chromosome arm 16q loss with loss of imprinting of insulin-like growth factor-II in Wilms tumor.

1 reference

12 December 2020

Physical localisation of the breakpoints of a constitutional translocation t(5;6)(q21;q21) in a child with bilateral Wilms' tumour.

1 reference

12 December 2020

Epigenetic lesions at the H19 locus in Wilms' tumour patients

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12 December 2020

Post-transcriptional regulation: the dawn of PTB.

1 reference

12 December 2020

Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney

1 reference

12 December 2020

Preferential loss of maternal alleles in sporadic Wilms' tumour.

1 reference

12 December 2020

Signal transduction of beta-catenin

1 reference

12 December 2020

WT1 (Wilms' tumor gene 1): biology and cancer immunotherapy

1 reference

12 December 2020

Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.

1 reference

12 December 2020

Wnt signaling and cancer

1 reference

12 December 2020

Evidence for WT1 as a Wilms tumor (WT) gene: intragenic germinal deletion in bilateral WT

1 reference

12 December 2020

COX-2 inhibitors in cancer treatment and prevention, a recent development

1 reference

12 December 2020

Kinetic behaviour of WT 1’s zinc finger domain in binding to the alpha-actinin-1 mRNA

1 reference

12 December 2020

WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis

1 reference

12 December 2020

An X chromosome gene, WTX, is commonly inactivated in Wilms tumor

1 reference

12 December 2020

WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene

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12 December 2020

The Wilms' tumor suppressor gene WT1 is negatively autoregulated

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12 December 2020

The molecular biology of Wilms' tumour

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12 December 2020

Molecular analysis of region t(5;6)(q21;q21) in Wilms tumor

1 reference

12 December 2020

Identification of limited regions of genetic aberrations in patients affected with Wilms' tumor using a tiling-path chromosome 22 array

1 reference

12 December 2020

Defining the region(s) of deletion at 6q16-q22 in human prostate cancer

1 reference

12 December 2020

A syndrome of pseudohermaphroditism, Wilms' tumor, hypertension, and degenerative renal disease

1 reference

12 December 2020

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

12 December 2020

Wilms tumor and the WT1 gene

1 reference

12 December 2020

Anaplastic Wilms' tumor: clinical and pathologic studies

1 reference

12 December 2020

The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin

1 reference

12 December 2020

Genetic linkage of Beckwith-Wiedemann syndrome to 11p15.

1 reference

12 December 2020

Imprinting of a genomic domain of 11p15 and loss of imprinting in cancer: an introduction

1 reference

12 December 2020

Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1

1 reference

12 December 2020

A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros

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12 December 2020

Activation of the wt1 Wilms' tumor suppressor gene by NF-kappaB.

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12 December 2020

The Wilms' tumour protein (WT1) shuttles between nucleus and cytoplasm and is present in functional polysomes

1 reference

12 December 2020

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

1 reference

12 December 2020

Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors

1 reference

12 December 2020

Delineation of a 1Mb breakpoint region at 1p13 in Wilms tumors by fine-tiling oligonucleotide array CGH

1 reference

12 December 2020

Aniridia-Wilms’ tumor association: evidence for specific deletion of 11p13

1 reference

12 December 2020

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

1 reference

12 December 2020

Effective treatment of leukemic cell lines with wt1 siRNA.

1 reference

12 December 2020

Two candidate tumor suppressor genes, MEOX2 and SOSTDC1, identified in a 7p21 homozygous deletion region in a Wilms tumor

1 reference

12 December 2020

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1 reference

12 December 2020

Topoisomerase IIalpha in Wilms' tumour: gene alterations and immunoexpression.

1 reference

12 December 2020

Syndromes and constitutional chromosomal abnormalities associated with Wilms tumour

1 reference

12 December 2020

Loss of heterozygosity at 7p in Wilms' tumour development

1 reference

12 December 2020

Clonal expansion and attenuated apoptosis in Wilms' tumors are associated with p53 gene mutations

1 reference

12 December 2020

PAX8-mediated activation of the wt1 tumor suppressor gene

1 reference

12 December 2020

Target genes of the WNT/beta-catenin pathway in Wilms tumors

1 reference

12 December 2020

Immunophenotype, mRNA expression, and gene structure of p53 in Wilms' tumors

1 reference

12 December 2020

Germline and somatic abnormalities of chromosome 7 in Wilms' tumor

1 reference

12 December 2020

WT1 induces apoptosis through transcriptional regulation of the proapoptotic Bcl-2 family member Bak.

1 reference

12 December 2020

Profiling of differential gene expression in Wilms tumor by cDNA expression array.

1 reference

12 December 2020

The Wilms' tumor suppressor protein WT1 is processed by the serine protease HtrA2/Omi

1 reference

12 December 2020

Negative regulation of bcl-2 expression by p53 in hematopoietic cells

1 reference

12 December 2020

Germline mutations of the POU6F2 gene in Wilms tumors with loss of heterozygosity on chromosome 7p14.

1 reference

12 December 2020

Kidneys and sex, the Wilms' tumor connection.

1 reference

12 December 2020

ErbB2 is a tumor associated antigen and a suitable therapeutic target in Wilms tumor

1 reference

12 December 2020

Histopathology and prognosis of Wilms tumorResults from the first national wilms' tumor study

1 reference

12 December 2020

1 reference

12 December 2020

The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1.

1 reference

12 December 2020

The virtuoso of versatility: POU proteins that flex to fit

1 reference

12 December 2020

Infrequent mutation of theWT1 gene in 77 Wilms' tumors

1 reference

12 December 2020

E-cadherin is a WT1 target gene

1 reference

12 December 2020

Anaplastic Wilms' tumour, a subtype displaying poor prognosis, harbours p53 gene mutations

1 reference

12 December 2020

WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny.

1 reference

12 December 2020

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

1 reference

12 December 2020

Identification of a novel parathyroid hormone-responsive gene in human osteoblastic cells

1 reference

12 December 2020

A tumor suppressor and oncogene: the WT1 story.

1 reference

12 December 2020

Current management of Wilms' tumor in children

1 reference

12 December 2020

Genetics of Wilms' tumor

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12 December 2020

p53 accumulation in favorable-histology Wilms tumor is associated with angiogenesis and clinically aggressive disease

1 reference

12 December 2020

ASSOCIATION OF WILMS'S TUMOR WITH ANIRIDIA, HEMIHYPERTROPHY AND OTHER CONGENITAL MALFORMATIONS

1 reference

12 December 2020

Molecular nature of genetic changes resulting in loss of heterozygosity of chromosome 11 in Wilms' tumours

1 reference

12 December 2020

Repression of Pax-2 by WT1 during normal kidney development

1 reference

12 December 2020

Transcript profiling of Wilms tumors reveals connections to kidney morphogenesis and expression patterns associated with anaplasia.

1 reference

12 December 2020

New isoform of the neuronal Ca2+ channel alpha1E subunit in islets of Langerhans and kidney--distribution of voltage-gated Ca2+ channel alpha1 subunits in cell lines and tissues

1 reference

12 December 2020

The paired-box transcription factor, PAX2, positively modulates expression of the Wilms' tumor suppressor gene (WT1)

1 reference

12 December 2020

Physical interaction between Wilms tumor 1 and p73 proteins modulates their functions.

1 reference

12 December 2020

SKCG-1: a new candidate growth regulatory gene at chromosome 11q23.2 in human sporadic Wilms tumours

1 reference

12 December 2020

Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence

1 reference

12 December 2020

Retina-derived POU-domain factor-1: a complex POU-domain gene implicated in the development of retinal ganglion and amacrine cells

1 reference

12 December 2020

Hypercalcemia and elevated parathyroid hormone levels in association with nephroblastoma

1 reference

12 December 2020

The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity

1 reference

12 December 2020

Anaplasia in unilateral Wilms' tumor: a report from the National Wilms' Tumor Study Pathology Center.

1 reference

12 December 2020

Sp1 is a critical regulator of the Wilms' tumor-1 gene

1 reference

12 December 2020

Paternally inherited submicroscopic duplication at 11p15.5 implicates insulin-like growth factor II in overgrowth and Wilms' tumorigenesis

1 reference

12 December 2020

Refinement within single yeast artificial chromosome clones of a minimal region commonly deleted on the short arm of chromosome 7 in Wilms tumours

1 reference

12 December 2020

Cytogenetic changes in Wilms' tumors

1 reference

12 December 2020

Functional interaction of beta-catenin with the transcription factor LEF-1

1 reference

12 December 2020

Physical and functional interaction between WT1 and p53 proteins

1 reference

12 December 2020

p53-dependent cell cycle control: response to genotoxic stress

1 reference

12 December 2020

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12 December 2020

Management of Wilms tumor: current standard of care

1 reference

12 December 2020

Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor

1 reference

12 December 2020

Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development

1 reference

12 December 2020

Current therapy for Wilms' tumor

1 reference

12 December 2020

WT1 splicing alterations in Wilms' tumors

1 reference

12 December 2020

The parathyroid hormone-responsive B1 gene is interrupted by a t(1;7)(q42;p15) breakpoint associated with Wilms' tumour

1 reference

12 December 2020

Genetic and epigenetic alterations on the short arm of chromosome 11 are involved in a majority of sporadic Wilms' tumours

1 reference

12 December 2020

Association of 11q loss, trisomy 12, and possible 16q loss with loss of imprinting of insulin-like growth factor-II in Wilms tumor

1 reference

12 December 2020

A 3-cM commonly deleted region in 6q21 in leukemias and lymphomas delineated by fluorescence in situ hybridization

1 reference

12 December 2020

Ultrastructure and histogenesis of the renal tumors of childhood: an overview

1 reference

12 December 2020

Biochimica et Biophysica Acta

67

1653

1

R.H. Giles

2003

1 reference

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Helvetica paediatrica acta

16 July 2024

82

34

459

J. Kraker de

1979

1 reference

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16 July 2024

Identifiers

1 reference

23 August 2017

1 reference