Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms (Q37702581)

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scientific article published on 20 January 2014

Language	Label	Description	Also known as
English	Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms	scientific article published on 20 January 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms (English)

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

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Denise S Fernandez-Twinn

object named as

Denise S Fernandez-Twinn

1

0 references

object named as

Susan E Ozanne

8

0 references

Malgorzata S Martin-Gronert

3

object named as

Malgorzata S Martin-Gronert

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

author name string

Maria Z Alfaradhi

2

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Daniella E Duque-Guimaraes

4

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Ana Piekarz

5

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

David Ferland-McCollough

6

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Martin Bushell

7

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

publication date

20 January 2014

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Europe PubMed Central

PMC publication ID

22 August 2017

Molecular Metabolism

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

325-333

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

The programming of cardiac hypertrophy in the offspring by maternal obesity is associated with hyperinsulinemia, AKT, ERK, and mTOR activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

Developmental programming in response to maternal overnutrition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

microRNAs in the Regulation of Adipogenesis and Obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

Maternal "junk-food" feeding of rat dams alters food choices and development of the mesolimbic reward pathway in the offspring.

1 reference

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Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism

1 reference

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Prevalence and trends in obesity among US adults, 1999-2008

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Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring

1 reference

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Altered skeletal muscle insulin signaling and mitochondrial complex II-III linked activity in adult offspring of obese mice

1 reference

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Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates

1 reference

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23 August 2017

Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight

1 reference

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23 August 2017

The cell growth suppressor, mir-126, targets IRS-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

In utero exposure to maternal obesity and diabetes: animal models that identify and characterize implications for future health.

1 reference

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23 August 2017

From obesity to diabetes

1 reference

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23 August 2017

Obesity and the role of adipose tissue in inflammation and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

Tissue-specific roles of IRS proteins in insulin signaling and glucose transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

Early origins of obesity: programming the appetite regulatory system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

Childhood obesity: the health issue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

23 August 2017

Fetal growth and developmental programming

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

6 September 2017

MicroRNAs in Development and Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

6 September 2017

Pathways linking the early environment to long-term health and lifespan.

1 reference

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6 September 2017

The involvement of microRNAs in Type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

6 September 2017

Sugar consumption and global prevalence of obesity and hypertension: an ecological analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

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Newly developed primary culture of rat visceral adipocytes and their in vitro characteristics

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Short-term in vivo inhibition of insulin receptor substrate-1 expression leads to insulin resistance, hyperinsulinemia, and increased adiposity.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

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Altered hepatic insulin signalling in male offspring of obese mice.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

1 September 2018

Maternal obesity during pregnancy and lactation programs the development of offspring non-alcoholic fatty liver disease in mice

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Effects of maternal surgical weight loss in mothers on intergenerational transmission of obesity

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Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression.

1 reference

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The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle.

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Glucose transporter 4 and insulin receptor substrate-1 messenger RNA expression in omental and subcutaneous adipose tissue in women

1 reference

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Established diet-induced obesity in female rats leads to offspring hyperphagia, adiposity and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

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Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

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Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance: a novel murine model of developmental programming

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1 September 2018

A maternal 'junk food' diet in pregnancy and lactation promotes an exacerbated taste for 'junk food' and a greater propensity for obesity in rat offspring

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986586

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Large maternal weight loss from obesity surgery prevents transmission of obesity to children who were followed for 2 to 18 years

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Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle

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Low birthweight is associated with specific changes in muscle insulin-signalling protein expression

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Insulin resistance with low cellular IRS-1 expression is also associated with low GLUT4 expression and impaired insulin-stimulated glucose transport

1 reference

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1 September 2018

Decreased protein levels of key insulin signalling molecules in adipose tissue from young men with a low birthweight: potential link to increased risk of diabetes?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24749062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obese visceral adipose tissue grafted in lean mice can alter glucose homeostasis and energy efficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/24749062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLMET.2014.01.007

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

ResearchGate publication ID

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