Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases. (Q37561567)

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scientific article published on 08 December 2013

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English	Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.	scientific article published on 08 December 2013

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2 March 2020

Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases (English)

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2 March 2020

Douglas A Coulter

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2 March 2020

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Hong Lin

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2 March 2020

Fu-Chun Hsu

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2 March 2020

Bailey H Baumann

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2 March 2020

David R Lynch

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2 March 2020

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8 December 2013

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2 March 2020

Neurobiology of Disease

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2 March 2020

63

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2 March 2020

129-140

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2 March 2020

Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction

1 reference

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23 August 2017

Encoding and transducing the synaptic or extrasynaptic origin of NMDA receptor signals to the nucleus

1 reference

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23 August 2017

Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications.

1 reference

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23 August 2017

Nicotinic mechanisms in the treatment of psychotic disorders: a focus on the α7 nicotinic receptor

1 reference

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23 August 2017

Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion

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23 August 2017

The role of glutamatergic inputs onto parvalbumin-positive interneurons: relevance for schizophrenia

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23 August 2017

Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors

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23 August 2017

α7-Nicotinic acetylcholine receptor: role in early odor learning preference in mice

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23 August 2017

Diversity in NMDA receptor composition: many regulators, many consequences

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23 August 2017

Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases

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23 August 2017

Genetic data supporting the NMDA glutamate receptor hypothesis for schizophrenia

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23 August 2017

Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia

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23 August 2017

15q11.2-13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain.

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23 August 2017

Delayed procedural learning in α7-nicotinic acetylcholine receptor knockout mice

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23 August 2017

Postnatal developmental trajectories of neural circuits in the primate prefrontal cortex: identifying sensitive periods for vulnerability to schizophrenia

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23 August 2017

MAGUKs, synaptic development, and synaptic plasticity

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23 August 2017

EphB controls NMDA receptor function and synaptic targeting in a subunit-specific manner

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23 August 2017

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior.

1 reference

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23 August 2017

Glutamate receptor subtypes mediating synaptic activation of prefrontal cortex neurons: relevance for schizophrenia

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23 August 2017

Trace Eyeblink Conditioning is Impaired in α7 but not in β2 Nicotinic Acetylcholine Receptor Knockout Mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3915878

23 August 2017

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

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23 August 2017

Axonal α7 nicotinic ACh receptors modulate presynaptic NMDA receptor expression and structural plasticity of glutamatergic presynaptic boutons

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23 August 2017

Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia

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23 August 2017

Glutamate receptor ion channels: structure, regulation, and function

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23 August 2017

Glutamatergic deficits and parvalbumin-containing inhibitory neurons in the prefrontal cortex in schizophrenia

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23 August 2017

Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

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23 August 2017

Targeting alpha7 nicotinic acetylcholine receptors in the treatment of schizophrenia

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23 August 2017

A small recurrent deletion within 15q13.3 is associated with a range of neurodevelopmental phenotypes

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23 August 2017

15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

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23 August 2017

Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior

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23 August 2017

Nicotinic alpha7- or beta2-containing receptor knockout: effects on radial-arm maze learning and long-term nicotine consumption in mice

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23 August 2017

Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders

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23 August 2017

EphB receptors co-distribute with a nicotinic receptor subtype and regulate nicotinic downstream signaling in neurons

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23 August 2017

A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures

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23 August 2017

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

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23 August 2017

Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory

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23 August 2017

N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease

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23 August 2017

Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission

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23 August 2017

Glutamate and nicotinic receptor interactions in working memory: importance for the cognitive impairment of schizophrenia

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6 September 2017

Targeting the nicotinic alpha7 acetylcholine receptor to enhance cognition in disease

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6 September 2017

Contributions of the D-serine pathway to schizophrenia.

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6 September 2017

Facilitation of glutamatergic neurotransmission by presynaptic nicotinic acetylcholine receptors

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6 September 2017

NMDA receptor and schizophrenia: a brief history

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25 June 2018

Twenty-five years of glutamate in schizophrenia: are we there yet?

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25 June 2018

Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons

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25 June 2018

NMDA receptor ablation on parvalbumin-positive interneurons impairs hippocampal synchrony, spatial representations, and working memory

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25 June 2018

Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics

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25 June 2018

Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists

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1 September 2018

Identification of single gene deletions at 15q13.3: further evidence that CHRNA7 causes the 15q13.3 microdeletion syndrome phenotype

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1 September 2018

The nicotinic α7 receptor agonist GTS-21 improves cognitive performance in ketamine impaired rhesus monkeys

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1 September 2018

Homozygous deletion of chromosome 15q13.3 including CHRNA7 causes severe mental retardation, seizures, muscular hypotonia, and the loss of KLF13 and TRPM1 potentially cause macrocytosis and congenital retinal dysfunction in siblings

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1 September 2018

CHRNA7 haplotypes are associated with impaired attention in euthymic bipolar disorder

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1 September 2018

Homozygous loss of CHRNA7 on chromosome 15q13.3 causes severe encephalopathy with seizures and hypotonia

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1 September 2018

Role of the NR2A/2B subunits of the N-methyl-D-aspartate receptor in glutamate-induced glutamic acid decarboxylase alteration in cortical GABAergic neurons in vitro.

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1 September 2018

A 15q13.3 homozygous microdeletion associated with a severe neurodevelopmental disorder suggests putative functions of the TRPM1, CHRNA7, and other homozygously deleted genes.

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1 September 2018

Alpha7 nicotinic acetylcholine receptor mRNA expression and binding in postmortem human brain are associated with genetic variation in neuregulin 1.

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1 September 2018

Interactions of postsynaptic density-95 and the NMDA receptor 2 subunit control calpain-mediated cleavage of the NMDA receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3915878

1 September 2018

Muscarinic and nicotinic presynaptic modulation of EPSCs in the nucleus accumbens during postnatal development

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1 September 2018

NMDA receptor function and human cognition: the effects of ketamine in healthy volunteers

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3915878

1 September 2018

A small homozygous microdeletion of 15q13.3 including the CHRNA7 gene in a girl with a spectrum of severe neurodevelopmental features

1 reference

https://pubmed.ncbi.nlm.nih.gov/24326163

12 December 2020

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Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice

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https://pubmed.ncbi.nlm.nih.gov/24326163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NBD.2013.11.021

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Europe PubMed Central

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2 March 2020

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Europe PubMed Central

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2 March 2020

PubMed publication ID

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Europe PubMed Central

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2 March 2020

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