To prevent, protect and save the ischemic heart: antioxidants revisited (Q37522464)

20 August 2017

1 reference

title

To prevent, protect and save the ischemic heart: antioxidants revisited (English)

1 reference

20 August 2017

3

Dimitrios Farmakis

1 reference

20 August 2017

Ioanna Andreadou

1

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20 August 2017

Efstathios K Iliodromitis

series ordinal

2

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20 August 2017

Dimitrios Th Kremastinos

series ordinal

4

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20 August 2017

language of work or name

English

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publication date

1 August 2009

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Expert Opinion on Therapeutic Targets

20 August 2017

published in

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20 August 2017

volume

13

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20 August 2017

issue

8

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20 August 2017

page(s)

945-956

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Oxidative stress and left ventricular remodelling after myocardial infarction

20 August 2017

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1 reference

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21 January 2018

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The measurement and mechanism of lipid peroxidation in biological systems

21 January 2018

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Alterations in cardiac contractile proteins due to oxygen free radicals

21 January 2018

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Coronary vasoregulation in patients with various risk factors in response to cold pressor testing: contrasting myocardial blood flow responses to short- and long-term vitamin C administration

21 January 2018

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The relation of lipid peroxidation processes with atherogenesis: a new theory on atherogenesis

21 January 2018

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Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site

21 January 2018

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Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity

21 January 2018

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The relationship of hydroxyeicosatetraenoic acids and F2-isoprostanes to plaque instability in human carotid atherosclerosis

21 January 2018

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Covered stent septal ablation for hypertrophic obstruction cardiomyopathy

21 January 2018

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Hypoxia causes an abnormal contractile response in the atherosclerotic rabbit aorta. Implication of reduced nitric oxide and cGMP production

21 January 2018

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Expression of extracellular SOD and iNOS in macrophages and smooth muscle cells in human and rabbit atherosclerotic lesions: colocalization with epitopes characteristic of oxidized LDL and peroxynitrite-modified proteins.

21 January 2018

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21 January 2018

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Endothelial function: cardiac events

21 January 2018

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Targeting antioxidants to mitochondria: a potential new therapeutic strategy for cardiovascular diseases.

21 January 2018

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Endothelial function, inflammation, and prognosis in cardiovascular disease

21 January 2018

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Images in cardiovascular medicine. Avoiding papillary muscle infarction with myocardial contrast echocardiographic guidance of nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903039698

Status of myocardial antioxidants in ischemia-reperfusion injury

21 January 2018

1 reference

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Internalization of human extracellular-superoxide dismutase by bovine aortic endothelial cells

21 January 2018

1 reference

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Antioxidant potentials of vitamin A and carotenoids and their relevance to heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Metoprolol prevents ischemia-reperfusion injury by reducing lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Ramipril-induced delayed myocardial protection against free radical injury involves bradykinin B2 receptor-NO pathway and protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Deferoxamine infusion during coronary artery bypass grafting ameliorates lipid peroxidation and protects the myocardium against reperfusion injury: immediate and long-term significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

The antioxidant effects of a novel iron chelator salicylaldehyde isonicotinoyl hydrazone in the prevention of H(2)O(2) injury in adult cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

The effect of diet on endothelial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Grape seed polyphenols protect cardiac cells from apoptosis via induction of endogenous antioxidant enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

White wine induced cardioprotection against ischemia-reperfusion injury is mediated by life extending Akt/FOXO3a/NFkappaB survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Resveratrol: A Therapeutic Promise for Cardiovascular Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Vitamin E consumption and the risk of coronary heart disease in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Vitamin C inhibits hypoxia-induced damage and apoptotic signaling pathways in cardiomyocytes and ischemic hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Alteration in cardiac sarcolemmal ATP receptors by oxyradicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Mechanism of dilation to reactive oxygen species in human coronary arterioles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Myocardial reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Limitation of myocardial infarct size in pigs with a dual lipoxygenase-cyclooxygenase blocking agent by inhibition of neutrophil activity without reduction of neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

The protective effect of desferal on rat myocardial mitochondria is not prolonged after withdrawal of desferal

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Alterations in heart membrane calcium transport during the development of ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

The role of neutrophils in myocardial ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Mitochondrial permeability transition pore opening as an endpoint to initiate cell death and as a putative target for cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Role of apoptosis in remodeling after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Reducing infarct size in the setting of acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Stunning, hibernation, and assessment of myocardial viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Reactive oxygen species, but not Ca2+ overloading, trigger pH- and mitochondrial permeability transition-dependent death of adult rat myocytes after ischemia-reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Na(+)/H(+) exchange inhibitors for cardioprotective therapy: progress, problems and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

The role of oxidants and free radicals in reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Direct measurement of free radical generation following reperfusion of ischemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Depletion of myocardial glutathione: its effects on heart function and metabolism during ischaemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Plasma antioxidant depletion after cardiopulmonary bypass in operations for congenital heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Reduction in experimental infarct size by recombinant human superoxide dismutase: insights into the pathophysiology of reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Improvement of postischemic myocardial function and metabolism induced by administration of deferoxamine at the time of reflow: the role of iron in the pathogenesis of reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Reperfusion-induced arrhythmias and oxygen-derived free radicals. Studies with "anti-free radical" interventions and a free radical-generating system in the isolated perfused rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Reduction of myocardial infarct size in rabbits by a novel indole derivative with antioxidant and free radical scavenging properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Overexpression of human copper, zinc-superoxide dismutase (SOD1) prevents postischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Postischemic recovery of contractile function is impaired in SOD2(+/-) but not SOD1(+/-) mouse hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Targeted disruption of the mouse Sod I gene makes the hearts vulnerable to ischemic reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

New concepts in reactive oxygen species and cardiovascular reperfusion physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Prodromal angina limits infarct size. A role for ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Medical and cellular implications of stunning, hibernation, and preconditioning: an NHLBI workshop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Ischemic preconditioning: emerging evidence, controversy, and translational trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Preconditioning the Myocardium: From Cellular Physiology to Clinical Cardiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Ischemic preconditioning: nearly two decades of research. A comprehensive review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Preconditioning of the ischaemic myocardium; involvement of the L-arginine nitric oxide pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Survival kinases in ischemic preconditioning and postconditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

The effectiveness of postconditioning and preconditioning on infarct size in hypercholesterolemic and normal anesthetized rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Protection from post-conditioning depends on the number of short ischemic insults in anesthetized pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Cardioprotection: spotlight on PKG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Postconditioning the human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Long-term benefit of postconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Staccato reperfusion prevents reperfusion injury in patients undergoing coronary angioplasty: a 1-year follow-up pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Free radicals, calcium homeostasis, heat shock proteins, and myocardial stunning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Essential role of oxygen radicals in delayed pharmacological preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Sarcolemmal versus mitochondrial ATP-sensitive K+ channels and myocardial preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Signal transduction of ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial K(ATP) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Postconditioning: a mechanical maneuver that triggers biological and molecular cardioprotective responses to reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Post-conditioning induced cardioprotection requires signaling through a redox-sensitive mechanism, mitochondrial ATP-sensitive K+ channel and protein kinase C activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Redox signaling at reperfusion is required for protection from ischemic preconditioning but not from a direct PKC activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Myocardial protection with postconditioning is not enhanced by ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Attenuation of ischemic preconditioning in pigs by scavenging of free oxyradicals with ascorbic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

A redox-based mechanism for cardioprotection induced by ischemic preconditioning in perfused rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Diazoxide-induced cardioprotection requires signaling through a redox-sensitive mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Superoxide dismutase and N-2-mercaptopropionyl glycine attenuate infarct size limitation effect of ischaemic preconditioning in the rabbit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Melatonin does not prevent the protection of ischemic preconditioning in vivo despite its antioxidant effect against oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Acute administration of vitamin E triggers preconditioning via K(ATP) channels and cyclic-GMP without inhibiting lipid peroxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

The effect of the phytoestrogen genistein on myocardial protection, preconditioning and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

Intermittent activation of bradykinin B2 receptors and mitochondrial KATP channels trigger cardiac postconditioning through redox signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903039698

10.1517/14728220903039698

21 January 2018

Identifiers

DOI

1 reference

20 August 2017

1 reference