Integrin-linked kinase regulates endothelial cell survival and vascular development. (Q37493087)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15340074%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Integrin-linked kinase regulates endothelial cell survival and vascular development (English)

1 reference

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1 January 2020

main subject

endothelium

0 references

Integrin-linked kinase

1 reference

GOA release 2020-03-11

author

Stuart Cook

4

1 reference

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1 January 2020

Thomas Force

9

1 reference

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1 January 2020

Shoukat Dedhar

12

1 reference

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1 January 2020

5

David S Milstone

1 reference

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1 January 2020

author name string

Erik B Friedrich

1

1 reference

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1 January 2020

Emerson Liu

2

1 reference

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1 January 2020

Sumita Sinha

3

1 reference

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1 January 2020

Calum A MacRae

6

1 reference

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1 January 2020

Massimo Mariotti

7

1 reference

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1 January 2020

Peter J Kuhlencordt

8

1 reference

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1 January 2020

Anthony Rosenzweig

10

1 reference

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1 January 2020

Rene St-Arnaud

11

1 reference

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1 January 2020

Robert E Gerszten

13

1 reference

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1 January 2020

language of work or name

English

0 references

publication date

1 September 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15340074%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15340074%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

24

1 reference

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1 January 2020

issue

18

1 reference

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1 January 2020

page(s)

8134-8144

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15340074%20AND%20SRC:MED&resulttype=core&format=json

Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelination

1 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Integrins: bidirectional, allosteric signaling machines

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Get a ligand, get a life: integrins, signaling and cell survival

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Regulation of endothelial cell survival and apoptosis during angiogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Placental development: lessons from mouse mutants

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Cell-substrate interactions and signaling through ILK

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Endothelial dysfunction, hemodynamic forces, and atherosclerosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Integrin-linked kinase and PINCH: partners in regulation of cell-extracellular matrix interaction and signal transduction.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Requirement of vascular integrin alpha v beta 3 for angiogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Integrin-linked kinase regulates chondrocyte shape and proliferation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Role of integrin-linked kinase in leukocyte recruitment.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Integrin-linked kinase expression increases with ovarian tumour grade and is sustained by peritoneal tumour fluid

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Regulation of tumor angiogenesis by integrin-linked kinase (ILK).

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Integrin-linked kinase expression increases with prostate tumor grade

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

Vasculogenesis in the day 6.5 to 9.5 mouse embryo.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515035

A critical role of the PINCH-integrin-linked kinase interaction in the regulation of cell shape change and migration

2 September 2018

1 reference

12 December 2020

Integrin-mediated death: an explanation of the integrin-knockout phenotype?

1 reference

12 December 2020

Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay

1 reference

12 December 2020

Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by Calcium

1 reference

12 December 2020

Activation-dependent isolation and culture of murine pulmonary microvascular endothelium

1 reference

12 December 2020

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

1 reference

12 December 2020

Microvascular endothelial cells from E-selectin-deficient mice form tubes in vitro

1 reference

12 December 2020

Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro

1 reference

12 December 2020

10.1128/MCB.24.18.8134-8144.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15340074%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15340074%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

15340074

1 reference