Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification (Q37421796)

20 August 2017

Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification (English)

1 reference

20 August 2017

Meghan E McGee-Lawrence

1

1 reference

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5 June 2020

Rajiv Kumar

6

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5 June 2020

author name string

Zachary C Ryan

2

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5 June 2020

Lomeli R Carpio

3

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5 June 2020

Sanjeev Kakar

4

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5 June 2020

Jennifer J Westendorf

5

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5 June 2020

language of work or name

English

0 references

publication date

6 November 2013

1 reference

Biochemical and Biophysical Research Communications

20 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24211207%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

441

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5 June 2020

issue

4

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5 June 2020

page(s)

886-890

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Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium

5 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Histone deacetylase 3 is required for maintenance of bone mass during aging

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Update on Wnt signaling in bone cell biology and bone disease.

23 August 2017

1 reference

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Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Wnt signaling during fracture repair

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone

23 August 2017

1 reference

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Osteocytes, mechanosensing and Wnt signaling

23 August 2017

1 reference

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Building bone to reverse osteoporosis and repair fractures

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Craniosynostosis caused by Axin2 deficiency is mediated through distinct functions of beta-catenin in proliferation and differentiation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Wnt signaling in osteoblasts and bone diseases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

High bone density due to a mutation in LDL-receptor-related protein 5

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Wnt proteins promote bone regeneration

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Time-dependent effects of sclerostin antibody on a mouse fracture healing model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Sclerostin antibody treatment improves bone mass, bone strength, and bone defect regeneration in rats with type 2 diabetes mellitus.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Strongly enhanced levels of sclerostin during human fracture healing.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

TGFbeta inducible early gene-1 knockout mice display defects in bone strength and microarchitecture.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

The incidence of fractures and dislocations referred for orthopaedic services in a capitated population.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876417

Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice

2 September 2018

1 reference

12 December 2020

Wnt signaling as a therapeutic target for bone diseases

1 reference

12 December 2020

Drilled hole defects in mouse femur as models of intramembranous cortical and cancellous bone regeneration

1 reference

12 December 2020

Increased callus mass and enhanced strength during fracture healing in mice lacking the sclerostin gene

1 reference

12 December 2020

10.1016/J.BBRC.2013.10.155

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24211207%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

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5 June 2020

PubMed publication ID

24211207

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24211207%20AND%20SRC:MED&resulttype=core&format=json