Mechanisms of insulin resistance in experimental hyperinsulinemic dogs (Q37377039)

20 August 2017

Mechanisms of insulin resistance in experimental hyperinsulinemic dogs (English)

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20 August 2017

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9

J M Olefsky

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20 August 2017

P. D. Miles

1

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1 December 2024

S. Li

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M. Hart

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1 December 2024

O. Romeo

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J. Cheng

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1 December 2024

A. Cohen

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K. Raafat

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1 December 2024

A. R. Moossa

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1 December 2024

language of work or name

English

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publication date

1 January 1998

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PMC publication ID

508557

full work available at URL

20 August 2017

http://www.jci.org/articles/view/1256/files/pdf

file format

Portable Document Format

online access status

open access

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https://europepmc.org/articles/PMC508557

1 December 2024

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https://europepmc.org/articles/PMC508557?pdf=render

1 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

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http://www.jci.org/articles/view/1256/files/pdf

1 December 2024

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https://api.crossref.org/works/10.1172/JCI1256

Journal of Clinical Investigation

1 December 2024

published in

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20 August 2017

101

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20 August 2017

1

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20 August 2017

202-211

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Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Epidemiologic studies on the pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM).

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

The effect of systemic venous drainage of the pancreas on insulin sensitivity in dogs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Influence of hyperglycemia on insulin's in vivo effects in type II diabetes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Metabolism of C-peptide in the dog. In vivo demonstration of the absence of hepatic extraction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Insulin transport across capillaries is rate limiting for insulin action in dogs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

In vivo stimulation of the insulin receptor kinase in human skeletal muscle. Correlation with insulin-stimulated glucose disposal during euglycemic clamp studies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Insulin and the vasculature--old actors, new roles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Hyperinsulinemia--how innocent a bystander?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Insulin receptors in human endothelial cells: identification and characterization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Quantitation of measurement error with Optimal Segments: basis for adaptive time course smoothing.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Importance of transcapillary insulin transport to dynamics of insulin action after intravenous glucose

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Use of Polyethylene Glycol to Separate Free and Antibody-Bound Peptide Hormones in Radioimmunoassays†

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Production of insulin resistance by hyperinsulinaemia in man.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Diversion of the gastroduodenal vein: an in situ model of systemic insulin drainage.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Peripheral effects of insulin dominate suppression of fasting hepatic glucose production

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Mechanisms of the kinetic defect in insulin action in obesity and NIDDM.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Thoracic duct lymph. Relative contribution from splanchnic and muscle tissue

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Delayed onset of insulin activation of the insulin receptor kinase in vivo in human skeletal muscle

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Kinetics of insulin action in vivo. Identification of rate-limiting steps

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508557

Pattern of postprandial carbohydrate metabolism and effects of portal and peripheral insulin delivery

2 September 2018

1 reference

12 December 2020

Dynamics of hepatic and peripheral insulin effects suggest common rate-limiting step in vivo

1 reference

12 December 2020

Insulin differentially regulates systemic and skeletal muscle vascular resistance

1 reference

12 December 2020

Predominance of renal and absence of hepatic metabolism of pancreatic polypeptide in the dog

1 reference

12 December 2020

Receptor and postreceptor insulin resistance induced by in vivo hyperinsuiinemia

1 reference

12 December 2020

Effects of portal and peripheral venous insulin infusion on glucose production and utilization in depancreatized, conscious dogs

1 reference

12 December 2020

A comparison of the effects of selective increases in peripheral or portal insulin on hepatic glucose production in the conscious dog

1 reference

12 December 2020

The role of fatty acids in mediating the effects of peripheral insulin on hepatic glucose production in the conscious dog

1 reference

12 December 2020

Receptor-mediated transport of insulin across endothelial cells

1 reference

12 December 2020

Comparison of portal and peripheral insulin delivery on carbohydrate metabolism in streptozotocin-diabetic rats

1 reference

12 December 2020

Direct and indirect effects of insulin to inhibit hepatic glucose output in obese subjects

1 reference

12 December 2020

Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates

1 reference

12 December 2020

Influences of glucose loading and of injected insulin on hepatic glucose output

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI1256

1 reference

20 August 2017

1 reference

PMC publication ID

508557

20 August 2017

1 reference

PMC publication ID

508557