Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression. (Q37340780)

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scientific article published on 16 October 2013

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English	Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.	scientific article published on 16 October 2013

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28 February 2020

Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression (English)

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28 February 2020

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Kazuichi Maruyama

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Kristian Pietras

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Gou Young Koh

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Yasuhiro Yoshimatsu

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Yulia G Lee

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Yuichi Akatsu

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Luna Taguchi

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Hiroshi I Suzuki

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Sara I Cunha

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Yuka Suzuki

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28 February 2020

Tomoko Yamazaki

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28 February 2020

Akihiro Katsura

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S Paul Oh

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28 February 2020

Se-Jin Lee

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28 February 2020

Kohei Miyazono

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28 February 2020

Tetsuro Watabe

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28 February 2020

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16 October 2013

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28 February 2020

Proceedings of the National Academy of Sciences of the United States of America

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28 February 2020

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18940-18945

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28 February 2020

BMP9 and BMP10 are critical for postnatal retinal vascular remodeling.

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ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway.

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ALK1 as an emerging target for antiangiogenic therapy of cancer

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BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo

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6 September 2017

Lymphangiogenesis: Molecular mechanisms and future promise

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Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell

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Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation

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6 September 2017

ALK1 signaling regulates early postnatal lymphatic vessel development

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Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia

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6 September 2017

Bone morphogenetic protein receptors and signal transduction

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6 September 2017

Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

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Bone morphogenetic protein-9 induces apoptosis in prostate cancer cells, the role of prostate apoptosis response-4

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Bone morphogenetic protein-9 is a circulating vascular quiescence factor

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6 September 2017

Molecular biology and pathology of lymphangiogenesis

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6 September 2017

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

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Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype.

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BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

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Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades

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Crystal structure of BMP-9 and functional interactions with pro-region and receptors

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An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

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Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.

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Ets family members induce lymphangiogenesis through physical and functional interaction with Prox1.

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T Lymphocytes Negatively Regulate Lymph Node Lymphatic Vessel Formation

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10.1073/PNAS.1310479110

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28 February 2020

2013PNAS..11018940Y

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