Innate immune modulation by RNA viruses: emerging insights from functional genomics (Q37226509)

19 August 2017

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title

Innate immune modulation by RNA viruses: emerging insights from functional genomics (English)

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19 August 2017

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4

Kathie-Anne Walters

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19 August 2017

1

Michael G Katze

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19 August 2017

Jamie L Fornek

2

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19 August 2017

Robert E Palermo

series ordinal

3

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19 August 2017

Marcus J Korth

series ordinal

5

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19 August 2017

publication date

1 August 2008

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Nature Reviews Immunology

19 August 2017

published in

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19 August 2017

volume

8

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19 August 2017

issue

8

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19 August 2017

page(s)

644-654

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1918 Influenza: the mother of all pandemics

19 August 2017

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Type I IFN receptor signals directly stimulate local B cells early following influenza virus infection

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Viruses and interferon: a fight for supremacy

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Principles of intracellular viral recognition.

31 March 2020

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Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response

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Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1

31 March 2020

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

31 March 2020

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Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

31 March 2020

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Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

31 March 2020

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Transcriptional profiling of the LPS induced NF-kappaB response in macrophages

31 March 2020

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Human macrophage activation programs induced by bacterial pathogens

31 March 2020

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Functional genomic delineation of TLR-induced transcriptional networks

31 March 2020

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Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

31 March 2020

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Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling

31 March 2020

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Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

31 March 2020

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Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

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Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease

31 March 2020

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31 March 2020

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31 March 2020

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

31 March 2020

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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

31 March 2020

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VISA is an adapter protein required for virus-triggered IFN-beta signaling

31 March 2020

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

31 March 2020

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DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infection

31 March 2020

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Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees

31 March 2020

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Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infection

31 March 2020

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Gene expression patterns that correlate with hepatitis C and early progression to fibrosis in liver transplant recipients

31 March 2020

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Distinct cellular responses differentiating alcohol- and hepatitis C virus-induced liver cirrhosis.

31 March 2020

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Identification of a specific gene expression pattern associated with HCV-induced pathogenesis in HCV- and HCV/HIV-infected individuals

31 March 2020

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Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response

31 March 2020

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Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection.

31 March 2020

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Intrahepatic gene expression profiles and alpha-smooth muscle actin patterns in hepatitis C virus induced fibrosis

31 March 2020

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Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector

31 March 2020

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Interferon regulatory factor-3 activation, hepatic interferon-stimulated gene expression, and immune cell infiltration in hepatitis C virus patients

31 March 2020

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Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence

31 March 2020

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Attenuated rabies virus activates, while pathogenic rabies virus evades, the host innate immune responses in the central nervous system

31 March 2020

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Suppression of the interferon-mediated innate immune response by pseudorabies virus

31 March 2020

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Hepatitis C virus infection

31 March 2020

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10-Year follow-up after interferon-alpha therapy for chronic hepatitis C.

31 March 2020

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Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

31 March 2020

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Hepatic gene expression discriminates responders and nonresponders in treatment of chronic hepatitis C viral infection

31 March 2020

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Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response

31 March 2020

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Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race

31 March 2020

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Changes in gene expression during pegylated interferon and ribavirin therapy of chronic hepatitis C virus distinguish responders from nonresponders to antiviral therapy

31 March 2020

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Lack of response to exogenous interferon-α in the liver of chimpanzees chronically infected with hepatitis C virus

31 March 2020

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Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1

31 March 2020

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Defective Hepatic Response to Interferon and Activation of Suppressor of Cytokine Signaling 3 in Chronic Hepatitis C

31 March 2020

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Immunopathogenesis of infectious disease: injury and death from friendly fire

31 March 2020

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The advent of the cytokine storm

31 March 2020

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Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic.

31 March 2020

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Use of functional genomics to understand influenza-host interactions.

31 March 2020

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A question of self-preservation: immunopathology in influenza virus infection.

31 March 2020

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Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

31 March 2020

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Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus.

31 March 2020

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Characterization of the reconstructed 1918 Spanish influenza pandemic virus

31 March 2020

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Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus

31 March 2020

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Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus

31 March 2020

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Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus

31 March 2020

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Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses

31 March 2020

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Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome

31 March 2020

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Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome

31 March 2020

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An interferon-gamma-related cytokine storm in SARS patients

31 March 2020

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Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques

31 March 2020

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Immunomics: discovering new targets for vaccines and therapeutics

31 March 2020

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Heterogeneity in vaccine immune response: the role of immunogenetics and the emerging field of vaccinomics

31 March 2020

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Bridging the knowledge gaps in vaccine design

31 March 2020

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Type I interferon dependence of plasmacytoid dendritic cell activation and migration.

31 March 2020

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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

31 March 2020

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A role for the transcription factor RelB in IFN-α production and in IFN-α-stimulated cross-priming

31 March 2020

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Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus.

31 March 2020

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Influenza virus evades innate and adaptive immunity via the NS1 protein

31 March 2020

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Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes.

31 March 2020

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Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine

31 March 2020

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Host-cell interaction of attenuated and wild-type strains of yellow fever virus can be differentiated at early stages of hepatocyte infection

31 March 2020

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Evasion of host defenses by measles virus: wild-type measles virus infection interferes with induction of Alpha/Beta interferon production

31 March 2020

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Transcriptional Activation of Interferon-Stimulated Genes but Not of Cytokine Genes after Primary Infection of Rhesus Macaques with Dengue Virus Type 1

31 March 2020

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The relevance of cytokines for development of protective immunity and rational design of vaccines

31 March 2020

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Transcriptional analysis of human peripheral blood mononuclear cells after influenza immunization.

31 March 2020

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Immune activation at effector and gene expression levels after measles vaccination in healthy individuals: a pilot study

31 March 2020

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HepatoProteomics: applying proteomic technologies to the study of liver function and disease

31 March 2020

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31 March 2020

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Viral proteomics: global evaluation of viruses and their interaction with the host

31 March 2020

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Integrated molecular signature of disease: analysis of influenza virus-infected macaques through functional genomics and proteomics

31 March 2020

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

31 March 2020

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Identification of microRNAs of the herpesvirus family

31 March 2020

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Identification of host proteins required for HIV infection through a functional genomic screen

31 March 2020

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COPI activity coupled with fatty acid biosynthesis is required for viral replication

31 March 2020

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Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology

31 March 2020

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Genetical genomics: combining genetics with gene expression analysis

31 March 2020

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An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypes

31 March 2020

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Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice

31 March 2020

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Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'.

31 March 2020

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Computational methodologies for modelling, analysis and simulation of signalling networks

31 March 2020

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The model organism as a system: integrating 'omics' data sets

31 March 2020

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Systems biology and the host response to viral infection

31 March 2020

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Microarray analysis: basic strategies for successful experiments

31 March 2020

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DNA microarray technology for the microbiologist: an overview

31 March 2020

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Chips with everything: DNA microarrays in infectious diseases

31 March 2020

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From functional genomics to functional immunomics: new challenges, old problems, big rewards

31 March 2020

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Microarray Profiling of Antibody Responses against Simian-Human Immunodeficiency Virus: Postchallenge Convergence of Reactivities Independent of Host Histocompatibility Type and Vaccine Regimen

31 March 2020

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Microarray profiling of antiviral antibodies for the development of diagnostics, vaccines, and therapeutics

31 March 2020

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Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses

31 March 2020

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Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

31 March 2020

1 reference

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

31 March 2020

1 reference

Type I IFN as a vaccine adjuvant for both systemic and mucosal vaccination against influenza virus

31 March 2020

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12 December 2020

Functional classification of interferon-stimulated genes identified using microarrays

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12 December 2020

Introduction to therapy of hepatitis C.

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12 December 2020

Type I IFNs enhance the terminal differentiation of dendritic cells

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12 December 2020

Hepatitis C virus and liver disease: global transcriptional profiling and identification of potential markers

1 reference

12 December 2020

Innate immune responses in human dendritic cells upon infection by chimeric yellow-fever dengue vaccine serotypes 1-4.

1 reference

12 December 2020

Pathogenic viruses: smart manipulators of the interferon system

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12 December 2020

Identifiers

DOI

10.1038/NRI2377

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Dimensions Publication ID

19 August 2017

1026942564

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PMC publication ID

7097543

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