SLP-76 sterile α motif (SAM) and individual H5 α helix mediate oligomer formation for microclusters and T-cell activation (Q37226140)

19 August 2017

SLP-76 sterile α motif (SAM) and individual H5 α helix mediate oligomer formation for microclusters and T-cell activation (English)

1 reference

19 August 2017

5

John E Ladbury

0 references

Youg Raj Thaker

object named as

Youg Raj Thaker

2

0 references

author name string

Hebin Liu

1

1 reference

19 August 2017

Loren Stagg

3

1 reference

19 August 2017

Helga Schneider

4

1 reference

19 August 2017

Christopher E Rudd

6

1 reference

19 August 2017

language of work or name

English

0 references

publication date

9 August 2013

1 reference

full work available at URL

19 August 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795252

0 references

published in

Journal of Biological Chemistry

1 reference

19 August 2017

288

1 reference

19 August 2017

41

1 reference

19 August 2017

29539-29549

1 reference

describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3795252/fullTextXML

inferred from PubMed Central ID database lookup

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6 September 2017

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The many faces of SAM

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6 September 2017

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6 September 2017

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Adaptors as central mediators of signal transduction in immune cells

6 September 2017

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T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

6 September 2017

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Native interface of the SAM domain polymer of TEL.

6 September 2017

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A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling

6 September 2017

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6 September 2017

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6 September 2017

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Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes

6 September 2017

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6 September 2017

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6 September 2017

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Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells

6 September 2017

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Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

6 September 2017

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FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

6 September 2017

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Adaptors and molecular scaffolds in immune cell signaling

6 September 2017

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Oligomeric structure of the human EphB2 receptor SAM domain

6 September 2017

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The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization

6 September 2017

1 reference

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Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

6 September 2017

1 reference

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Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

6 September 2017

1 reference

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SAM as a protein interaction domain involved in developmental regulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function.

6 September 2017

1 reference

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Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Three domains of SLP-76 are required for its optimal function in a T cell line

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Identifying polymer-forming SAM domains

28 September 2017

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26 June 2018

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Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

TCR signal transduction: opening the black box.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

T cell receptor-interacting molecule acts as a chaperone to modulate surface expression of the CTLA-4 coreceptor.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Development and testing of an automated approach to protein docking

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795252

Requirement for the SLP-76 adaptor GADS in T cell development

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23935094

12 December 2020

inferred from PubMed ID database lookup

SLP-76 binding to p56lck: a role for SLP-76 in CD4-induced desensitization of the TCR/CD3 signaling complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23935094

12 December 2020

inferred from PubMed ID database lookup

Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23935094

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M112.424846

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

23935094

1 reference