Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate (Q37174550)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

Middle East respiratory syndrome coronavirus

20 February 2020

main subject

0 references

0 references

1 reference

1 reference

Middle East respiratory syndrome

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Isabel Sola

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Sonia Zúñiga

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Silvia Márquez-Jurado

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

German Andrés

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Luis Enjuanes

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

5

Jose L Nieto-Torres

1 reference

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20 February 2020

2

Marta L DeDiego

1 reference

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20 February 2020

publication date

10 September 2013

1 reference

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20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

4

1 reference

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20 February 2020

issue

5

1 reference

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20 February 2020

page(s)

e00650-13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

Alphacoronavirus protein 7 modulates host innate immune response

20 February 2020

cites work

1 reference

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6 September 2017

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The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies

6 September 2017

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Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection

6 September 2017

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Hospital outbreak of Middle East respiratory syndrome coronavirus

6 September 2017

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Update: Severe respiratory illness associated with Middle East Respiratory Syndrome Coronavirus (MERS-CoV)--worldwide, 2012-2013.

6 September 2017

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Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission

6 September 2017

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Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus

6 September 2017

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Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

6 September 2017

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Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe

6 September 2017

1 reference

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MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

6 September 2017

1 reference

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Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin

6 September 2017

1 reference

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Complete protection against severe acute respiratory syndrome coronavirus-mediated lethal respiratory disease in aged mice by immunization with a mouse-adapted virus lacking E protein

6 September 2017

1 reference

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Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures

6 September 2017

1 reference

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Pneumonia from human coronavirus in a macaque model

6 September 2017

1 reference

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Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

6 September 2017

1 reference

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Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome coronavirus

6 September 2017

1 reference

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Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans

6 September 2017

1 reference

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A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease

6 September 2017

1 reference

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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

6 September 2017

1 reference

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Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction

6 September 2017

1 reference

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Molecular characterization of feline infectious peritonitis virus strain DF-2 and studies of the role of ORF3abc in viral cell tropism.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Detection of alpha and betacoronaviruses in multiple Iberian bat species

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Cell-type-specific type I interferon antagonism influences organ tropism of murine coronavirus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Coronavirus gene 7 counteracts host defenses and modulates virus virulence

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Accessory protein 5a is a major antagonist of the antiviral action of interferon against murine coronavirus

6 September 2017

1 reference

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Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease

6 September 2017

1 reference

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Coronaviruses post-SARS: update on replication and pathogenesis

6 September 2017

1 reference

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Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice

6 September 2017

1 reference

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Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice.

6 September 2017

1 reference

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Chimeric coronavirus-like particles carrying severe acute respiratory syndrome coronavirus (SCoV) S protein protect mice against challenge with SCoV

6 September 2017

1 reference

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Immune responses against severe acute respiratory syndrome coronavirus induced by virus-like particles in mice

6 September 2017

1 reference

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Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease

6 September 2017

1 reference

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Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features

6 September 2017

1 reference

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A severe acute respiratory syndrome coronavirus that lacks the E gene is attenuated in vitro and in vivo

6 September 2017

1 reference

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Construction of a severe acute respiratory syndrome coronavirus infectious cDNA clone and a replicon to study coronavirus RNA synthesis.

6 September 2017

1 reference

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Recovery of a neurovirulent human coronavirus OC43 from an infectious cDNA clone

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Immunogenicity and protective efficacy in monkeys of purified inactivated Vero-cell SARS vaccine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

The small envelope protein E is not essential for murine coronavirus replication

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Engineering the transmissible gastroenteritis virus genome as an expression vector inducing lactogenic immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Coronaviruses maintain viability despite dramatic rearrangements of the strictly conserved genome organization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Generation of a replication-competent, propagation-deficient virus vector based on the transmissible gastroenteritis coronavirus genome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Induction of apoptosis in murine coronavirus-infected cultured cells and demonstration of E protein as an apoptosis inducer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Complete Nucleotide Sequence of Two Generations of a Bacterial Artificial Chromosome Cloning Vector

6 September 2017

1 reference

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Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells

6 September 2017

1 reference

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Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Absence of E protein arrests transmissible gastroenteritis coronavirus maturation in the secretory pathway.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

The nucleoprotein is required for efficient coronavirus genome replication.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Transmissible gastroenteritis coronavirus gene 7 is not essential but influences in vivo virus replication and virulence.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

First cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in France, investigations and implications for the prevention of human-to-human transmission, France, May 2013.

27 June 2018

1 reference

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Evidence of person-to-person transmission within a family cluster of novel coronavirus infections, United Kingdom, February 2013.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Novel coronavirus associated with severe respiratory disease: case definition and public health measures.

3 September 2018

1 reference

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A double-inactivated whole virus candidate SARS coronavirus vaccine stimulates neutralising and protective antibody responses

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Immunogenicity, safety, and protective efficacy of an inactivated SARS-associated coronavirus vaccine in rhesus monkeys

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774192

The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24023385

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MBIO.00650-13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

release_mo3pppwdwbhm5htdzf3zgdxwsq

20 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mo3pppwdwbhm5htdzf3zgdxwsq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

24023385

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023385%20AND%20SRC:MED&resulttype=core&format=json