DNA repair genes are selectively mutated in diffuse large B cell lymphomas (Q37125781)

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7 March 2020

title

DNA repair genes are selectively mutated in diffuse large B cell lymphomas (English)

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7 March 2020

1

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Kristina Lagerstedt Robinson

7 March 2020

9

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7 March 2020

Susana Lisboa

10

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7 March 2020

Tom Van Wezel

12

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7 March 2020

Manuel R. Teixeira

13

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7 March 2020

Qiang Pan-Hammarström

20

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7 March 2020

16

Gunilla Enblad

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7 March 2020

author name string

Roujun Peng

2

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7 March 2020

Konstantinos Georgiou

3

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7 March 2020

Chenglin Wu

4

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7 March 2020

Elin Falk Sörqvist

5

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7 March 2020

Mattias Berglund

6

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7 March 2020

Longyun Chen

7

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7 March 2020

Zhibo Gao

8

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7 March 2020

Fredrik Roos

11

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7 March 2020

Richard Rosenquist

14

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7 March 2020

Christer Sundström

15

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7 March 2020

Mats Nilsson

17

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7 March 2020

Yixin Zeng

18

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7 March 2020

David Kipling

19

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7 March 2020

language of work or name

English

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publication date

19 August 2013

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Journal of Experimental Medicine

7 March 2020

published in

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7 March 2020

volume

210

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7 March 2020

issue

9

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7 March 2020

page(s)

1729-1742

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Genetic heterogeneity of diffuse large B-cell lymphoma

7 March 2020

cites work

1 reference

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14 September 2017

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DNA repair dysregulation from cancer driver to therapeutic target

14 September 2017

1 reference

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Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks

14 September 2017

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Comprehensive molecular characterization of human colon and rectal cancer

14 September 2017

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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

14 September 2017

1 reference

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Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis

14 September 2017

1 reference

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DNA repair: the link between primary immunodeficiency and cancer

14 September 2017

1 reference

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Analysis of the coding genome of diffuse large B-cell lymphoma

14 September 2017

1 reference

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Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

14 September 2017

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Phase I Study of PARP Inhibitor ABT-888 in Combination with Topotecan in Adults with Refractory Solid Tumors and Lymphomas

14 September 2017

1 reference

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The variant call format and VCFtools

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Prediction of missense mutation functionality depends on both the algorithm and sequence alignment employed

14 September 2017

1 reference

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A framework for variation discovery and genotyping using next-generation DNA sequencing data

14 September 2017

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Integrative genomics viewer

14 September 2017

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Targeted resequencing of candidate genes using selector probes.

14 September 2017

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Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching

14 September 2017

1 reference

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The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets

14 September 2017

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A method and server for predicting damaging missense mutations

14 September 2017

1 reference

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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

14 September 2017

1 reference

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Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

BFAST: an alignment tool for large scale genome resequencing

14 September 2017

1 reference

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Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

14 September 2017

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VarScan: variant detection in massively parallel sequencing of individual and pooled samples

14 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

The Sequence Alignment/Map format and SAMtools

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Fast and accurate short read alignment with Burrows-Wheeler transform

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

SNP detection for massively parallel whole-genome resequencing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination

14 September 2017

1 reference

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Non-homologous end joining in class switch recombination: the beginning of the end

14 September 2017

1 reference

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Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg?

14 September 2017

1 reference

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Germinal centres: role in B-cell physiology and malignancy

14 September 2017

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CHK2 kinase: cancer susceptibility and cancer therapy - two sides of the same coin?

14 September 2017

1 reference

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Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts

14 September 2017

1 reference

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Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma

14 September 2017

1 reference

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Molecular mechanisms of antibody somatic hypermutation.

14 September 2017

1 reference

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The multifaceted mismatch-repair system

14 September 2017

1 reference

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Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus

14 September 2017

1 reference

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14 September 2017

1 reference

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

14 September 2017

1 reference

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Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

14 September 2017

The Chk2 protein kinase

1 reference

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A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Mechanisms of chromosomal translocations in B cell lymphomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

DNA double strand break repair and chromosomal translocation: lessons from animal models

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Reduction of GC --> TA transversion mutation by overexpression of MutS in Escherichia coli K-12.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Mutation in the Mismatch Repair Gene Msh6 Causes Cancer Susceptibility

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Rare germ line CHEK2 variants identified in breast cancer families encode proteins that show impaired activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Two levels of protection for the B cell genome during somatic hypermutation.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

AID is required for germinal center-derived lymphomagenesis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Regulation of CHK2 by DNA-dependent protein kinase

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

AID is required for c-myc/IgH chromosome translocations in vivo

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

The role of hMLH3 in familial colorectal cancer

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Msh2 DNA mismatch repair gene deficiency and the food-borne mutagen 2-amino-1-methy1-6-phenolimidazo [4,5-b] pyridine (PhIP) synergistically affect mutagenesis in mouse colon

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754869

Molecular pathogenesis of diffuse large B-cell lymphoma

3 September 2018

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12 December 2020

Automated genotyping using the DNA MassArray technology

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12 December 2020

Transcriptional compensation for loss of an allele of the Ini1 tumor suppressor

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12 December 2020

8q Gain Is an Independent Predictor of Poor Survival in Diagnostic Needle Biopsies from Prostate Cancer Suspects

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12 December 2020

Identifiers

DOI

10.1084/JEM.20122842

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23960188%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23960188%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

23960188

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23960188%20AND%20SRC:MED&resulttype=core&format=json