The many spaces of uPAR: delivery of theranostic agents and nanobins to multiple tumor compartments through a single target (Q36997621)

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5 March 2020

1 reference

8 February 2021

The many spaces of uPAR: delivery of theranostic agents and nanobins to multiple tumor compartments through a single target (English)

1 reference

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urokinase plasminogen activator surface receptor

5 March 2020

main subject

1 reference

15 December 2019

1 reference

26 October 2020

1 reference

8 February 2021

urokinase-type plasminogen activator

object of statement has role

subject heading

object named as

urokinase plasminogen activator

1 reference

PubMed publication ID

2

1 reference

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5 March 2020

author name string

Thomas V O'Halloran

1

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5 March 2020

Patrick Hankins

3

1 reference

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5 March 2020

Elden Swindell

4

1 reference

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5 March 2020

Andrew P Mazar

5

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5 March 2020

language of work or name

1 reference

25 June 2013

8 references

3 April 2019

25 June 2019

31 July 2019

15 December 2019

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1 June 2020

26 October 2020

8 February 2021

7 references

25 June 2019

31 July 2019

15 December 2019

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1 June 2020

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8 February 2021

3

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issue

7

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5 March 2020

page(s)

496-506

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Creative Commons Attribution-NonCommercial-NoDerivatives

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copyright license

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3 April 2019

25 June 2019

31 July 2019

15 December 2019

1 June 2020

26 October 2020

8 February 2021

on focus list of Wikimedia project

ScienceSource

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Enhanced noscapine delivery using uPAR-targeted optical-MR imaging trackable nanoparticles for prostate cancer therapy

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Cell Signaling by Urokinase-type Plasminogen Activator Receptor Induces Stem Cell–like Properties in Breast Cancer Cells

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A reexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals and covalently conjugated peptide ligands

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Structure-based Engineering of Species Selectivity in the Interaction between Urokinase and Its Receptor: IMPLICATION FOR PRECLINICAL CANCER THERAPY

29 September 2017

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Randomized study of Lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer

29 September 2017

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RNAi-mediated downregulation of uPAR synergizes with targeting of HER2 through the ERK pathway in breast cancer cells

29 September 2017

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Regulation of cell signalling by uPAR.

29 September 2017

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Urokinase plasminogen activator system as a potential target for cancer therapy.

29 September 2017

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Coencapsulation of arsenic- and platinum-based drugs for targeted cancer treatment

29 September 2017

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Receptor-targeted nanoparticles for in vivo imaging of breast cancer

29 September 2017

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Targeting the urokinase plasminogen activator receptor with a monoclonal antibody impairs the growth of human colorectal cancer in the liver

29 September 2017

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Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

29 September 2017

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Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator

29 September 2017

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Urokinase plasminogen activator receptor choreographs multiple ligand interactions: implications for tumor progression and therapy

29 September 2017

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29 September 2017

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29 September 2017

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The urokinase-system--role of cell proliferation and apoptosis

29 September 2017

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Development and evaluation of peptidic ligands targeting tumour-associated urokinase plasminogen activator receptor (uPAR) for use in alpha-emitter therapy for disseminated ovarian cancer

29 September 2017

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29 September 2017

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29 September 2017

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Identification of uPAR-positive chemoresistant cells in small cell lung cancer

29 September 2017

1 reference

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uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues

29 September 2017

1 reference

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Integrin-regulated FAK-Src signaling in normal and cancer cells

29 September 2017

1 reference

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Structure of human urokinase plasminogen activator in complex with its receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Drug delivery systems: entering the mainstream

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

CD87 (urokinase-type plasminogen activator receptor), function and pathology in hematological disorders: a review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Urokinase receptor and integrin interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Tumour-cell invasion and migration: diversity and escape mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

uPAR: a versatile signalling orchestrator

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Expression of urokinase plasminogen activator and the urokinase plasminogen activator receptor in myeloma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Enhanced expression of urokinase plasminogen activator and its receptor in pancreatic carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

An anti-urokinase plasminogen activator receptor antibody (ATN-658) blocks prostate cancer invasion, migration, growth, and experimental skeletal metastasis in vitro and in vivo.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Putative cancer stem cells in malignant pleural mesothelioma show resistance to cisplatin and pemetrexed

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Polymer-caged lipsomes: a pH-responsive delivery system with high stability

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Plasticity in urokinase-type plasminogen activator receptor (uPAR) display in colon cancer yields metastable subpopulations oscillating in cell surface uPAR density--implications in tumor progression.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Spectral imaging perspective on cytomics.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

Urokinase-type plasminogen activator receptor regulates a novel pathway of fibronectin matrix assembly requiring Src-dependent transactivation of epidermal growth factor receptor

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

In situ gene expression of urokinase-type plasminogen activator and its receptor in transitional cell carcinoma of the human bladder.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

The soluble D2D3(88-274) fragment of the urokinase receptor inhibits monocyte chemotaxis and integrin-dependent cell adhesion

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706693

The prognostic value of the topographic distribution of uPAR expression in invasive breast carcinomas

4 September 2018

1 reference

12 December 2020

uPAR-uPA-PAI-1 interactions and signaling: a vascular biologist's view

1 reference

12 December 2020

ErbB2 overexpression on occult metastatic cells in bone marrow predicts poor clinical outcome of stage I-III breast cancer patients

1 reference

12 December 2020

The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A

1 reference

12 December 2020

Recombinant toxins that bind to the urokinase receptor are cytotoxic without requiring binding to the alpha(2)-macroglobulin receptor

1 reference

12 December 2020

Involvement of PA/plasmin system in the processing of pro-MMP-9 and in the second step of pro-MMP-2 activation

1 reference

12 December 2020

Efficacy of antiangiogenic targeted toxins against glioblastoma multiforme

1 reference

12 December 2020

Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

1 reference

12 December 2020

Individual development and uPA-receptor expression of disseminated tumour cells in bone marrow: a reference to early systemic disease in solid cancer

1 reference

12 December 2020

Immunohistochemical detection of the receptor for urokinase plasminogen activator in human colon cancer

1 reference

12 December 2020

Identifiers

DOI

10.7150/THNO.4953

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843897%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843897%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

23843897

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843897%20AND%20SRC:MED&resulttype=core&format=json