New insights into adaptive immunity in chronic neuroinflammation (Q36991434)

17 August 2017

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title

New insights into adaptive immunity in chronic neuroinflammation (English)

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17 August 2017

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4

Frauke Zipp

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author name string

Volker Siffrin

series ordinal

1

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17 August 2017

Alexander U Brandt

series ordinal

2

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17 August 2017

Josephine Herz

series ordinal

3

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17 August 2017

publication date

1 January 2007

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17 August 2017

published in

Advances in Immunology

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17 August 2017

volume

96

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17 August 2017

page(s)

1-40

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Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin

17 August 2017

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Restriction of de novo pyrimidine biosynthesis inhibits Th1 cell activation and promotes Th2 cell differentiation

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Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease.

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The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms

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Immunotherapy of experimental autoimmune encephalomyelitis (EAE): Differential effect of anti-IL-2 receptor antibody therapy on actively induced and T-line mediated EAE of the Lewis rat

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Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases

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7 January 2021

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T-lymphocyte entry into the central nervous system

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7 January 2021

Does the frequency and avidity spectrum of the neuroantigen-specific T cells in the blood mirror the autoimmune process in the central nervous system of mice undergoing experimental allergic encephalomyelitis?

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7 January 2021

Kinetics and organ distribution of IL-17-producing CD4 cells in proteolipid protein 139-151 peptide-induced experimental autoimmune encephalomyelitis of SJL mice

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Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune Encephalomyelitis

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Autoimmune intervention by CD154 blockade prevents T cell retention and effector function in the target organ

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Normal Th1 development following long-term therapeutic blockade of CD154-CD40 in experimental autoimmune encephalomyelitis

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7 January 2021

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Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists

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Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells

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Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis

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Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis

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CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis

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7 January 2021

Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial

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7 January 2021

Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system.

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7 January 2021

Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

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Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis

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A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cells

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7 January 2021

Acute disseminated encephalomyelitis: an update

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7 January 2021

A controlled trial of natalizumab for relapsing multiple sclerosis

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7 January 2021

Contact with central nervous system myelin inhibits oligodendrocyte progenitor maturation.

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7 January 2021

Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis

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7 January 2021

Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy

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7 January 2021

Natalizumab effects on immune cell responses in multiple sclerosis

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7 January 2021

Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

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7 January 2021

Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells.

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7 January 2021

A Phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses

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7 January 2021

Quantitative MRI in patients with secondary progressive MS treated with monoclonal antibody Campath 1H.

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7 January 2021

Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency

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7 January 2021

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

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7 January 2021

TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes

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7 January 2021

Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions

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7 January 2021

Glutamate excitotoxicity in a model of multiple sclerosis

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7 January 2021

A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

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7 January 2021

Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis

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7 January 2021

Cerebrospinal fluid analysis: disease-related data patterns and evaluation programs

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7 January 2021

Glucocorticoids in multiple sclerosis and experimental autoimmune encephalomyelitis

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Triggering of T cell proliferation through CD28 induces GATA-3 and promotes T helper type 2 differentiation in vitro and in vivo

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7 January 2021

Chimeric cytotoxin IL2-PE40 inhibits relapsing experimental allergic encephalomyelitis

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https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Treatment of multiple sclerosis with an anti-interleukin-2 receptor monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Natalizumab plus interferon beta-1a for relapsing multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

MRI and CSF oligoclonal bands after autologous hematopoietic stem cell transplantation in MS.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Chemoattractants and their receptors in homeostasis and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Experimental autoimmune encephalomyelitis in intercellular adhesion molecule-1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Safety of rosuvastatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

The role of alpha-4 integrin in the aetiology of multiple sclerosis: current knowledge and therapeutic implications

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

T-lymphocyte subsets in the multiple sclerosis lesion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Frequencies of neuroantigen-specific T cells in the central nervous system versus the immune periphery during the course of experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Heterogeneity in the B1 (CD20) cell surface molecule expressed by human B-lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Oligoclonal immunoglobulins and plasma cells in spinal fluid of patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Axonal Transection in the Lesions of Multiple Sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Multiple sclerosis☆Distribution of T cells, T cell subsets and Ia-positive macrophages in lesions of different ages

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Multiple Sclerosis: Distribution of T Cell Subsets Within Active Chronic Lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

The expression and function of chemokines involved in CNS inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Autoantibody-mediated demyelination depends on complement activation but not activatory Fc-receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Herpes simplex virus encephalitis: Intrathecal synthesis of oligoclonal virus-specific IgG, IgA and IgM antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation. Daclizumab Triple Therapy Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Oral simvastatin treatment in relapsing-remitting multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Atorvastatin induces T cell anergy via phosphorylation of ERK1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Augmentation of adoptively transferred experimental allergic encephalomyelitis by administration of a monoclonal antibody specific for LFA-1α

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

T cell receptor V alpha-V beta repertoire and cytokine gene expression in active multiple sclerosis lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Immune (dys)regulation in multiple sclerosis: role of the CD95-CD95 ligand system.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

Blockade of chemokine signaling in patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

PARTICLES RESEMBLING PAPOVA VIRUSES IN HUMAN CEREBRAL DEMYELINATING DISEASE.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2807%2996001-0

7 January 2021

10.1016/S0065-2776(07)96001-0

Identifiers

DOI

1 reference

17 August 2017

1 reference