Mapping protein post-translational modifications with mass spectrometry (Q36954374)

17 August 2017

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title

Mapping protein post-translational modifications with mass spectrometry (English)

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17 August 2017

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Eric S Witze

1

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17 August 2017

William M Old

series ordinal

2

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17 August 2017

Katheryn A Resing

series ordinal

3

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17 August 2017

Natalie G Ahn

series ordinal

4

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17 August 2017

publication date

1 October 2007

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17 August 2017

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17 August 2017

volume

4

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17 August 2017

issue

10

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17 August 2017

page(s)

798-806

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Mass spectrometry-based proteomics

17 August 2017

cites work

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7 January 2021

Mass spectrometry of peptides and proteins

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7 January 2021

Informatics for protein identification by mass spectrometry

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7 January 2021

The origins of protein phosphorylation

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7 January 2021

Large-scale characterization of HeLa cell nuclear phosphoproteins

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7 January 2021

Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation

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7 January 2021

Electron capture dissociation of singly and multiply phosphorylated peptides

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7 January 2021

Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry

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7 January 2021

Electron capture dissociation for structural characterization of multiply charged protein cations

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7 January 2021

Selective detection and sequencing of phosphopeptides at the femtomole level by mass spectrometry

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7 January 2021

Rapid and selective modification of phosphoserine residues catalysed by Ba2+ ions for their detection during peptide microsequencing

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7 January 2021

Sequence analysis of phosphoserine-containing peptides. Modification for picomolar sensitivity

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7 January 2021

Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome

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7 January 2021

Phosphoprotein isotope-coded solid-phase tag approach for enrichment and quantitative analysis of phosphopeptides from complex mixtures.

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7 January 2021

Enhancement of ionization efficiency and selective enrichment of phosphorylated peptides from complex protein mixtures using a reversible poly-histidine tag.

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7 January 2021

A new derivatization strategy for the analysis of phosphopeptides by precursor ion scanning in positive ion mode

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7 January 2021

Phosphospecific proteolysis for mapping sites of protein phosphorylation

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7 January 2021

Improved beta-elimination-based affinity purification strategy for enrichment of phosphopeptides

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7 January 2021

Deamidation as a consequence of beta-elimination of phosphopeptides

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7 January 2021

Susceptibility of the hydroxyl groups in serine and threonine to β-elimination/Michael addition under commonly used moderately high-temperature conditions

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7 January 2021

Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry

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7 January 2021

An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells

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7 January 2021

Reproducible isolation of distinct, overlapping segments of the phosphoproteome

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7 January 2021

Isolation of phosphoproteins by immobilized metal (Fe3+) affinity chromatography

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7 January 2021

Immobilized gallium(III) affinity chromatography of phosphopeptides

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7 January 2021

Selective zirconium dioxide-based enrichment of phosphorylated peptides for mass spectrometric analysis

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7 January 2021

Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns.

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7 January 2021

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules

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7 January 2021

Large-scale phosphorylation analysis of mouse liver

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7 January 2021

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

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7 January 2021

Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics

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7 January 2021

Identification of novel phosphorylation sites on Xenopus laevis Aurora A and analysis of phosphopeptide enrichment by immobilized metal-affinity chromatography

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7 January 2021

Large-scale Analysis ofin VivoPhosphorylated Membrane Proteins by Immobilized Metal Ion Affinity Chromatography and Mass Spectrometry

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7 January 2021

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

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7 January 2021

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

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7 January 2021

Role of accurate mass measurement (+/- 10 ppm) in protein identification strategies employing MS or MS/MS and database searching.

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7 January 2021

Optimization and use of peptide mass measurement accuracy in shotgun proteomics

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7 January 2021

Peptide sequence motif analysis of tandem MS data with the SALSA algorithm

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7 January 2021

ModifiComb, a new proteomic tool for mapping substoichiometric post-translational modifications, finding novel types of modifications, and fingerprinting complex protein mixtures.

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7 January 2021

Identification of post-translational modifications by blind search of mass spectra.

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7 January 2021

Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry

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7 January 2021

Analysis of protein phosphorylation in the regions of consecutive serine/threonine residues by negative ion electrospray collision-induced dissociation. Approach to pinpointing of phosphorylation sites

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7 January 2021

Metabolic labeling of proteins for proteomics

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7 January 2021

Mass spectrometry-based proteomics turns quantitative

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7 January 2021

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

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7 January 2021

An isotope coding strategy for proteomics involving both amine and carboxyl group labeling

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7 January 2021

Proteolytic 18O labeling for comparative proteomics: model studies with two serotypes of adenovirus

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7 January 2021

Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents

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7 January 2021

Quantification of proteins and metabolites by mass spectrometry without isotopic labeling or spiked standards

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7 January 2021

Comparison of label-free methods for quantifying human proteins by shotgun proteomics.

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7 January 2021

Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites

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7 January 2021

Differential mass spectrometry: a label-free LC-MS method for finding significant differences in complex peptide and protein mixtures

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7 January 2021

Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

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7 January 2021

Absolute quantification of multisite phosphorylation by selective reaction monitoring mass spectrometry: determination of inhibitory phosphorylation status of cyclin-dependent kinases

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7 January 2021

Protein phosphorylation analysis by electrospray ionization-mass spectrometry

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7 January 2021

Studies of ligand-induced site-specific phosphorylation of epidermal growth factor receptor

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7 January 2021

A quantitative results-driven approach to analyzing multisite protein phosphorylation: the phosphate-dependent phosphorylation profile of the transcription factor Pho4.

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7 January 2021

An isotope labeling strategy for quantifying the degree of phosphorylation at multiple sites in proteins

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7 January 2021

Characterization of histones and their post-translational modifications by mass spectrometry

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7 January 2021

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

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7 January 2021

A newly discovered post-translational modification--the acetylation of serine and threonine residues

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7 January 2021

Lysine propionylation and butyrylation are novel post-translational modifications in histones

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7 January 2021

Ubiquitin as a central cellular regulator

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7 January 2021

Direct identification of a G protein ubiquitination site by mass spectrometry

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7 January 2021

A proteomics approach to understanding protein ubiquitination

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7 January 2021

Electron transfer dissociation of peptide anions

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7 January 2021

Fourier transform ion cyclotron resonance mass spectrometry for the analysis of small ubiquitin-like modifier (SUMO) modification: identification of lysines in RanBP2 and SUMO targeted for modification during the E3 autoSUMOylation reaction

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7 January 2021

Proteomic insights into ubiquitin and ubiquitin-like proteins.

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7 January 2021

Automated identification of SUMOylation sites using mass spectrometry and SUMmOn pattern recognition software

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7 January 2021

Polyubiquitin chains: polymeric protein signals

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7 January 2021

A method of mapping protein sumoylation sites by mass spectrometry using a modified small ubiquitin-like modifier 1 (SUMO-1) and a computational program.

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7 January 2021

Context of multiubiquitin chain attachment influences the rate of Sic1 degradation

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7 January 2021

A proteomics approach to identify the ubiquitinated proteins in mouse heart

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7 January 2021

A new method of purification of proteasome substrates reveals polyubiquitination of 20 S proteasome subunits.

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7 January 2021

Enrichment and analysis of peptide subsets using fluorous affinity tags and mass spectrometry

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7 January 2021

UbiProt: a database of ubiquitylated proteins

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7 January 2021

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

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7 January 2021

Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence

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7 January 2021

Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B.

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7 January 2021

Redox signaling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers

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7 January 2021

Receptor-regulated dynamic S-nitrosylation of endothelial nitric-oxide synthase in vascular endothelial cells

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7 January 2021

Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking

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7 January 2021

SNOSID, a proteomic method for identification of cysteine S-nitrosylation sites in complex protein mixtures

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7 January 2021

Identification of S-nitrosylation motifs by site-specific mapping of the S-nitrosocysteine proteome in human vascular smooth muscle cells

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7 January 2021

Protein S-nitrosylation: a physiological signal for neuronal nitric oxide

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7 January 2021

Protein sulfenation as a redox sensor: proteomics studies using a novel biotinylated dimedone analogue

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7 January 2021

Inhibition of protein-tyrosine phosphatases by mild oxidative stresses is dependent on S-nitrosylation.

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7 January 2021

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

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7 January 2021

Quantitative proteomic assessment of very early cellular signaling events

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7 January 2021

Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction

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7 January 2021

SUMOsp: a web server for sumoylation site prediction

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7 January 2021

O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks

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7 January 2021

Mutual interactions between the SUMO and ubiquitin systems: a plea of no contest

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7 January 2021

Quantitative analysis of phosphotyrosine signaling networks triggered by CD3 and CD28 costimulation in Jurkat cells

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7 January 2021

Detection and localization of protein modifications by high resolution tandem mass spectrometry

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7 January 2021

Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

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7 January 2021

Identifiers

DOI

10.1038/NMETH1100

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17 August 2017

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