The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering. (Q36843122)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10069803%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering (English)

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11 November 2019

1

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11 November 2019

Réjane Paumelle

2

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11 November 2019

author name string

K M Weidner

3

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11 November 2019

B Vandenbunder

4

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11 November 2019

V Fafeur

5

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11 November 2019

language of work or name

1 reference

1 March 1999

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Molecular Biology of the Cell

11 November 2019

published in

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11 November 2019

volume

10

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11 November 2019

issue

3

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11 November 2019

page(s)

551-565

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10069803%20AND%20SRC:MED&resulttype=core&format=json

Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

11 November 2019

cites work

1 reference

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Association of the Multisubstrate Docking Protein Gab1 with the Hepatocyte Growth Factor Receptor Requires a Functional Grb2 Binding Site Involving Tyrosine 1356

29 September 2017

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The ETS1 transcription factor is expressed during epithelial-mesenchymal transitions in the chick embryo and is activated in scatter factor-stimulated MDCK epithelial cells.

29 September 2017

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Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase

29 September 2017

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Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility

29 September 2017

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29 September 2017

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Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction

29 September 2017

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A Grb2-associated docking protein in EGF- and insulin-receptor signalling

29 September 2017

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Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

29 September 2017

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

29 September 2017

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Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

29 September 2017

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Molecular aspects of mesenchymal-epithelial interactions

29 September 2017

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SH2/SH3 signaling proteins

29 September 2017

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Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

29 September 2017

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

29 September 2017

1 reference

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Autophosphorylation mutants of the EGF-receptor signal through auxiliary mechanisms involving SH2 domain proteins.

29 September 2017

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Receptor protein-tyrosine kinases and their signal transduction pathways

29 September 2017

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Regulation of urokinase-type plasminogen activator gene transcription by macrophage colony-stimulating factor.

29 September 2017

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The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein

29 September 2017

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Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.

29 September 2017

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

29 September 2017

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An incomplete program of cellular tyrosine phosphorylations induced by kinase-defective epidermal growth factor receptors

29 September 2017

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

29 September 2017

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Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

29 September 2017

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29 September 2017

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The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites

29 September 2017

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Transcription factor PEA3 participates in the induction of urokinase plasminogen activator transcription in murine keratinocytes stimulated with epidermal growth factor or phorbol-ester

29 September 2017

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The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation

29 September 2017

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Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

29 September 2017

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Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor

29 September 2017

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The met proto-oncogene receptor and lumen formation

29 September 2017

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Overexpression of the Sky receptor tyrosine kinase at the cell surface or in the cytoplasm results in ligand-independent activation.

29 September 2017

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The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells

29 September 2017

1 reference

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Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor).

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25187

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

27 June 2018

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A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25187

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25187

Tyrosine kinase receptor indistinguishable from the c-met protein

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25187

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

27 June 2018

1 reference

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The c-ets-1 proto-oncogene is a new early-response gene differentially regulated by cytokines and growth factors in human fibroblasts

27 June 2018

1 reference

12 December 2020

Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats

1 reference

12 December 2020

A simple in vitro model of mechanical injury of confluent cultured endothelial cells to study quantitatively the repair process

1 reference

12 December 2020

Phosphatidylinositol 3-kinase activity is required for hepatocyte growth factor-induced mitogenic signals in epithelial cells

1 reference

12 December 2020

Tyrosine 1356 in the carboxyl-terminal tail of the HGF/SF receptor is essential for the transduction of signals for cell motility and morphogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.10.3.551

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10069803%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10069803%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

PubMed publication ID

10069803

1 reference