Molecular "negativity" may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS. (Q36832884)

16 August 2017

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title

Molecular "negativity" may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS. (English)

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16 August 2017

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1 reference

George Harauz

2

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author name string

Abdiwahab A Musse

series ordinal

1

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16 August 2017

publication date

1 January 2007

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International Review of Neurobiology

16 August 2017

published in

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16 August 2017

volume

79

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16 August 2017

page(s)

149-172

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Localization of peptidylarginine deiminase type II in a stage-specific immature oligodendrocyte from rat cerebral hemisphere

16 August 2017

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A combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes

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7 January 2021

Axonal damage in acute multiple sclerosis lesions

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Mechanisms of ionotropic glutamate receptor-mediated excitotoxicity in isolated spinal cord white matter

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7 January 2021

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7 January 2021

Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Molecules affecting myelin stability: a novel hypothesis regarding the pathogenesis of multiple sclerosis

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7 January 2021

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7 January 2021

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7 January 2021

Modifications of myelin basic protein in DM20 transgenic mice are similar to those in myelin basic protein from multiple sclerosis

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7 January 2021

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Assessing protein disorder and induced folding

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Multilamellar packing of myelin modeled by lipid-bound MBP

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Over-expression of the DM-20 myelin proteolipid causes central nervous system demyelination in transgenic mice

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Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein

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7 January 2021

Immunology of multiple sclerosis

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Structural disorder throws new light on moonlighting

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Axonal Transection in the Lesions of Multiple Sclerosis

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7 January 2021

Exogenous myelin basic protein promotes oligodendrocyte death via increased calcium influx

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Localization and partial characterization of a 60 kDa citrulline-containing transport form of myelin basic protein from MO3-13 cells and human white matter

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7 January 2021

Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients

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Citrullination: a small change for a protein with great consequences for rheumatoid arthritis

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PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease

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7 January 2021

Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

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7 January 2021

Is the myelin membrane abnormal in multiple sclerosis?

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7 January 2021

Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein

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7 January 2021

The mighty arginine, the stable quaternary amines, the powerful aromatics, and the aggressive phosphate: their role in the noncovalent minuet

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7 January 2021

Amazing stability of the arginine-phosphate electrostatic interaction

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7 January 2021

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

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7 January 2021

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

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7 January 2021

Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones

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7 January 2021

Recognition of the immunodominant myelin basic protein peptide by autoantibodies and HLA-DR2-restricted T cell clones from multiple sclerosis patients. Identity of key contact residues in the B-cell and T-cell epitopes

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The pathobiology of myelin mutants reveal novel biological functions of the MBP and PLP genes.

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DOI

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16 August 2017

1 reference