Synthesis and medical applications of oligosaccharides (Q36802338)

16 August 2017

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title

Synthesis and medical applications of oligosaccharides (English)

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16 August 2017

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1

Peter H Seeberger

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16 August 2017

Daniel B Werz

2

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16 August 2017

language of work or name

English

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publication date

1 April 2007

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16 August 2017

number of pages

6

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inferred from page(s)

published in

Nature

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16 August 2017

volume

446

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16 August 2017

issue

7139

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16 August 2017

page(s)

1046-1051

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Human genomics and medicine

16 August 2017

cites work

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1 Concept and early development of solid-phase peptide synthesis

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Toward Fully Synthetic Homogeneous Glycoproteins: A High Mannose Core Containing Glycopeptide Carrying Full H-Type 2 Human Blood Group Specificity This work was supported by the National Institutes of Health (Grant nos.: HL-25848 and CA-28824 (to S.

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Congruent strategies for carbohydrate sequencing. 1. Mining structural details by MSn

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Glycome mapping on DNA sequencing equipment

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Glycoprotein structure determination by mass spectrometry

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Sequencing complex polysaccharides

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7 January 2021

Preparation and structural determination of large oligosaccharides derived from acharan sulfate

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Heparin sequencing using enzymatic digestion and ESI-MSn with HOST: a heparin/HS oligosaccharide sequencing tool

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High-throughput protein glycomics: combined use of chemoselective glycoblotting and MALDI-TOF/TOF mass spectrometry.

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Toward automated synthesis of oligosaccharides and glycoproteins

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Enzymes for chemical synthesis

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7 January 2021

Advances in the production of human therapeutic proteins in yeasts and filamentous fungi

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Optimization of humanized IgGs in glycoengineered Pichia pastoris.

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7 January 2021

Automated solid-phase synthesis of oligosaccharides

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7 January 2021

Solid-phase oligosaccharide synthesis: preparation of complex structures using a novel linker and different glycosylating agents

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7 January 2021

Automated solid-phase synthesis of protected tumor-associated antigen and blood group determinant oligosaccharides

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7 January 2021

Automated synthesis of the tumor-associated carbohydrate antigens Gb-3 and Globo-H: incorporation of alpha-galactosidic linkages

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7 January 2021

Genomics, gene expression and DNA arrays

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7 January 2021

Global analysis of protein activities using proteome chips

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7 January 2021

Carbohydrate microarrays for the recognition of cross-reactive molecular markers of microbes and host cells

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7 January 2021

Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions

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7 January 2021

Fabrication of carbohydrate chips for studying protein-carbohydrate interactions

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7 January 2021

Synthesis of sugar arrays in microtiter plate

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7 January 2021

Carbohydrate arrays for the evaluation of protein binding and enzymatic modification

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7 January 2021

Encoded Fiber‐Optic Microsphere Arrays for Probing Protein–Carbohydrate Interactions

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7 January 2021

Carbohydrate microarrays: survey of fabrication techniques.

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7 January 2021

Probing protein-carbohydrate interactions with microarrays of synthetic oligosaccharides

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7 January 2021

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

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7 January 2021

Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions

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7 January 2021

Sugar-mediated ligand-receptor interactions in the immune system

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7 January 2021

Sweet spots in functional glycomics

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7 January 2021

Aminoglycoside microarrays to explore interactions of antibiotics with RNAs and proteins

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7 January 2021

Aminoglycoside microarrays to study antibiotic resistance.

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7 January 2021

The use of carbohydrate microarrays to study carbohydrate-cell interactions and to detect pathogens

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7 January 2021

Intact cell adhesion to glycan microarrays

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7 January 2021

Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus

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7 January 2021

Microarrays of synthetic heparin oligosaccharides.

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7 January 2021

Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

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7 January 2021

Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions.

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7 January 2021

Discovery of a TNF-alpha antagonist using chondroitin sulfate microarrays

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7 January 2021

Sulfation patterns of glycosaminoglycans encode molecular recognition and activity

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7 January 2021

Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria

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7 January 2021

Antibodies against laminaribioside and chitobioside are novel serologic markers in Crohn's disease

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen

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7 January 2021

Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns

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7 January 2021

Analyzing the dynamic bacterial glycome with a lectin microarray approach.

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7 January 2021

Antiviral agents active against influenza A viruses.

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7 January 2021

Tamiflu: the supply problem

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7 January 2021

Heparin-protein interactions

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7 January 2021

1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site

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7 January 2021

A synthetic antithrombin III binding pentasaccharide is now a drug! What comes next?

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7 January 2021

Chemical approaches to define the structure-activity relationship of heparin-like glycosaminoglycans

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

A modular strategy toward the synthesis of heparin-like oligosaccharides using monomeric building blocks in a sequential glycosylation strategy

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

The activation of fibroblast growth factors by heparin: synthesis, structure, and biological activity of heparin-like oligosaccharides.

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Synthesis of heparin oligosaccharides

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Tumor-Associated Carbohydrate Antigens Defining Tumor Malignancy: Basis for Development of Anti-Cancer Vaccines

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7 January 2021

Recent developments in bacterial conjugate vaccines

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7 January 2021

From the Laboratory to the Clinic: A Retrospective on Fully Synthetic Carbohydrate-Based Anticancer Vaccines Frequently used abbreviations are listed in the appendix

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Selection of tumor antigens as targets for immune attack using immunohistochemistry: I. Focus on gangliosides

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Carbohydrate vaccines as immunotherapy for cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Carbohydrate-protein conjugate vaccines

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

A synthetic conjugate polysaccharide vaccine against Haemophilus influenzae type b

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Novel oligosaccharide side chains of the collagen-like region of BclA, the major glycoprotein of the Bacillus anthracis exosporium

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Total synthesis of antigen bacillus anthracis tetrasaccharide--creation of an anthrax vaccine candidate

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Synthesis of the beta anomer of the spacer-equipped tetrasaccharide side chain of the major glycoprotein of the Bacillus anthracis exosporium

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Anti-carbohydrate antibodies for the detection of anthrax spores

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Conservation of structure among glycosylphosphatidylinositol toxins from different geographic isolates of Plasmodium falciparum

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

The lipophosphoglycan of Leishmania parasites

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Automated solid-phase synthesis of a branched Leishmania cap tetrasaccharide

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Enhancement of the immunogenicity of synthetic carbohydrates by conjugation to virosomes: a leishmaniasis vaccine candidate

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Gold Glyconanoparticles as Water-Soluble Polyvalent Models To Study Carbohydrate Interactions This work was supported by the DGICYT (PB96-0820), J.M.F. thanks the MEC for a predoctoral fellowship. A.G.B. thanks CSIC for financial support. We thank P

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Tools for glycomics: mapping interactions of carbohydrates in biological systems

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Site-specific multivalent carbohydrate labeling of quantum dots and magnetic beads

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

A New Chemical Probe for Proteomics of Carbohydrate-Binding Proteins

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Detection of bacteria with carbohydrate-functionalized fluorescent polymers.

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https://api.crossref.org/works/10.1038%2FNATURE05819

7 January 2021

Identifiers

DOI

10.1038/NATURE05819

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16 August 2017

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