Foxp3 in control of the regulatory T cell lineage (Q36794299)

16 August 2017

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title

Foxp3 in control of the regulatory T cell lineage (English)

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16 August 2017

2

Alexander Y Rudensky

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16 August 2017

Ye Zheng

1

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16 August 2017

language of work or name

English

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publication date

1 May 2007

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16 August 2017

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16 August 2017

volume

8

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issue

5

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16 August 2017

page(s)

457-462

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A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

16 August 2017

cites work

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7 January 2021

Foxp3 and natural regulatory T cells: key to a cell lineage?

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7 January 2021

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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7 January 2021

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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7 January 2021

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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7 January 2021

JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

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7 January 2021

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

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Control of regulatory T cell development by the transcription factor Foxp3

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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FOXP3: of mice and men.

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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

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Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

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HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells

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Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

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Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.

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Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter

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Functional adaptive CD4 Foxp3 T cells develop in MHC class II-deficient mice

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Peripheral T cell lymphopenia and concomitant enrichment in naturally arising regulatory T cells: the case of the pre-Talpha gene-deleted mouse

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7 January 2021

Early events in the thymus affect the balance of effector and regulatory T cells

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The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis

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Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

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An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

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Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

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Origin of regulatory T cells with known specificity for antigen

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The role of the transcription factor Foxp3 in the development of regulatory T cells

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Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

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Foxp3-dependent programme of regulatory T-cell differentiation

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Regulatory T cell development in the absence of functional Foxp3.

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Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

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Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

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Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

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Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation

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Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

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Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways

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Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor

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Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.

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Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation

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FOXP3 controls regulatory T cell function through cooperation with NFAT

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Foxp3 occupancy and regulation of key target genes during T-cell stimulation

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A role for Dicer in immune regulation

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Identifiers

DOI

10.1038/NI1455

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16 August 2017

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