A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells (Q36781051)

16 August 2017

A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells (English)

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polycystic kidney disease

16 August 2017

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5

Scott A Ness

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16 August 2017

1

Tamara Roitbak

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16 August 2017

Angela Wandinger-Ness

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6

object named as

Angela Wandinger-Ness

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16 August 2017

Christopher J Ward

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16 August 2017

Peter C Harris

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3

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16 August 2017

Robert Bacallao

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4

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16 August 2017

12 January 2004

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Molecular Biology of the Cell

16 August 2017

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16 August 2017

15

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16 August 2017

3

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16 August 2017

1334-1346

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describes a project that uses

16 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC363138/fullTextXML

inferred from PubMed Central ID database lookup

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N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane

29 September 2017

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Polycystin-1 activates and stabilizes the polycystin-2 channel.

29 September 2017

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PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2

29 September 2017

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Functional polycystin-1 expression is developmentally regulated during epithelial morphogenesis in vitro: downregulation and loss of membrane localization during cystogenesis

29 September 2017

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Retention of membrane-localized beta-catenin in cells lacking functional polycystin-1 and tuberin

29 September 2017

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The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells

29 September 2017

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29 September 2017

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29 September 2017

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Cadherin-mediated cell sorting not determined by binding or adhesion specificity

29 September 2017

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29 September 2017

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Cadherin junctions in mammary tumors

29 September 2017

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Polycystin-1 transforms the cAMP growth-responsive phenotype of M-1 cells

29 September 2017

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E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner

29 September 2017

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Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene

29 September 2017

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Cadherin sequences that inhibit beta-catenin signaling: a study in yeast and mammalian cells

29 September 2017

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Polycystin: new aspects of structure, function, and regulation

29 September 2017

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Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel

29 September 2017

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The cadherin superfamily: diversity in form and function

29 September 2017

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Molecular genetics and pathogenesis of autosomal dominant polycystic kidney disease

29 September 2017

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Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

29 September 2017

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Cadherins and catenins, Wnts and SOXs: embryonic patterning in Xenopus

29 September 2017

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Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation

29 September 2017

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An ever-expanding story of cyst formation

29 September 2017

1 reference

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Compromised cytoarchitecture and polarized trafficking in autosomal dominant polycystic kidney disease cells

29 September 2017

1 reference

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Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins

29 September 2017

1 reference

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Embryonic renal epithelia: induction, nephrogenesis, and cell differentiation

29 September 2017

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Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics

29 September 2017

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Cadherins and tissue formation: integrating adhesion and signaling

29 September 2017

1 reference

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The oncogenic activation of beta-catenin

29 September 2017

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The polycystic kidney disease 1 gene product modulates Wnt signaling

29 September 2017

1 reference

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Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

29 September 2017

1 reference

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Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein

29 September 2017

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Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion

29 September 2017

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Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney

29 September 2017

1 reference

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Cell adhesion: the molecular basis of tissue architecture and morphogenesis

29 September 2017

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The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

Molecular genetics of polycystic kidney disease

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

Molecular and functional analysis of cadherin-based adherens junctions

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

N-cadherin is stably associated with and is an acceptor for a cell surface N-acetylgalactosaminylphosphotransferase.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

Protein kinase C inhibits the transplasma membrane influx of Ca2+ triggered by 4-aminopyridine in Jurkat T lymphocytes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

Protein kinase C inhibits ROMK1 channel activity via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

Beta-catenin interacts with low-molecular-weight protein tyrosine phosphatase leading to cadherin-mediated cell-cell adhesion increase.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

Loss of homotypic epithelial cell adhesion by selective N-cadherin displacement in bismuth nephrotoxicity.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

ADPKD: a human disease altering Golgi function and basolateral exocytosis in renal epithelia.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

Polycystin expression is temporally and spatially regulated during renal development.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=363138

Identification of phosphorylation sites in the PKD1-encoded protein C-terminal domain

5 September 2018

1 reference

12 December 2020

Cellular localization and tissue distribution of polycystin-1

1 reference

12 December 2020

Polycystin-1 expression in PKD1, early-onset PKD1, and TSC2/PKD1 cystic tissue

1 reference

12 December 2020

Polycystin-1 interacts with E-cadherin and the catenins--clues to the pathogenesis of cyst formation in ADPKD?

1 reference

12 December 2020

Cadherin switching in human prostate cancer progression

1 reference

12 December 2020

Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene

1 reference

12 December 2020

The Position of the Polycystic Kidney Disease 1 (PKD1) Gene Mutation Correlates with the Severity of Renal Disease

1 reference

12 December 2020

Cyst-derived cells do not exhibit accelerated growth or features of transformed cells in vitro

1 reference

12 December 2020

Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

1 reference

12 December 2020

The Polycystic Kidney Disease 1 Gene Product Mediates Protein Kinase C α-dependent and c-Jun N-terminal Kinase-dependent Activation of the Transcription Factor AP-1

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E03-05-0296

1 reference

16 August 2017

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16 August 2017

PubMed publication ID

14718571

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