Peroxisome proliferator-activated receptors ligands and ischemia-reperfusion injury (Q36774010)

16 August 2017

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title

Peroxisome proliferator-activated receptors ligands and ischemia-reperfusion injury (English)

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16 August 2017

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2

Salvatore Cuzzocrea

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16 August 2017

1

Rosanna Di Paola

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16 August 2017

publication date

13 March 2007

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Naunyn-Schmiedeberg's Archives of Pharmacology

16 August 2017

published in

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16 August 2017

volume

375

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16 August 2017

issue

3

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16 August 2017

page(s)

157-175

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Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT).

16 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00210-007-0141-2

Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway

21 January 2018

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Pleiotropic effects of thiazolidinediones: taking a look beyond antidiabetic activity.

21 January 2018

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Features of astrocytic function apparently involved in the response of central nervous tissue to ischemia-hypoxia

21 January 2018

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The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase

21 January 2018

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Signal transduction pathways of apoptosis and inflammation induced by the tumor necrosis factor receptor family

21 January 2018

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Troglitazone administration limits infarct size by reduced phosphorylation of canine myocardial connexin43 proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00210-007-0141-2

Roles of PPAR delta in lipid absorption and metabolism: a new target for the treatment of type 2 diabetes.

21 January 2018

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Platelet-activating factor mediates intercellular adhesion molecule-1-dependent radical production in the nonhypoxic ischemia rat lung

21 January 2018

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Efficacy of administering an endothelin-receptor antagonist (SB209670) in ameliorating ischemia-reperfusion injury in lung allografts

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00210-007-0141-2

Cell damage in the brain: a speculative synthesis

21 January 2018

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The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00210-007-0141-2

Impaired Ras membrane association and activation in PPARalpha knockout mice after partial hepatectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-007-0141-2

Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-007-0141-2

Anoxia-reoxygenation versus ischemia in isolated rat lungs

21 January 2018

1 reference

12 December 2020

Hepatic microcirculatory perfusion failure is a determinant of liver dysfunction in warm ischemia-reperfusion.

1 reference

12 December 2020

Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy

1 reference

12 December 2020

Angiotensin II stimulates expression of the chemokine RANTES in rat glomerular endothelial cells. Role of the angiotensin type 2 receptor

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12 December 2020

Cerebral resuscitation after cardiac arrest: a review

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12 December 2020

Apoptotic and necrotic cell death induced by death domain receptors.

1 reference

12 December 2020

Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury

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12 December 2020

Endothelial mechanosensors. Going with the flow

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12 December 2020

Differential induction of PPAR-gamma by luminal glutamine and iNOS by luminal arginine in the rodent postischemic small bowel

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12 December 2020

The PPAR-alpha activator fenofibrate fails to provide myocardial protection in ischemia and reperfusion in pigs

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12 December 2020

Chronic activation of PPARalpha is detrimental to cardiac recovery after ischemia

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12 December 2020

Protection against myocardial ischaemia/reperfusion injury by PPAR-alpha activation is related to production of nitric oxide and endothelin-1.

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12 December 2020

The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation.

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12 December 2020

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12 December 2020

Peroxisome proliferator-activated receptor gamma: the more the merrier?

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12 December 2020

An oral platelet-activating factor antagonist, Ro-24-4736, protects the rat kidney from ischemic injury

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12 December 2020

Cerebral ischemia. II. The no-reflow phenomenon

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12 December 2020

Local liberation of cytokines during liver preservation.

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12 December 2020

Protective effect of endogenous PPARgamma against acute gastric mucosal lesions associated with ischemia-reperfusion

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12 December 2020

5-lipoxygenase knockout mice exhibit a resistance to splanchnic artery occlusion shock

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12 December 2020

Nitric oxide-releasing compounds inhibit neutrophil adhesion to endothelial cells

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12 December 2020

Splenectomy-reduced hepatic injury induced by ischemia/reperfusion in the rat

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12 December 2020

PPARalpha ligands activate antioxidant enzymes and suppress hepatic fibrosis in rats

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12 December 2020

Consequences of activation and adenosine-mediated inhibition of granulocytes during myocardial ischemia

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12 December 2020

ATP-independent membrane depolarization with ischemia in the oxygen-ventilated isolated rat lung

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12 December 2020

Beneficial effects of PPAR-gamma ligands in ischemia-reperfusion injury, inflammation and shock

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12 December 2020

Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo

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12 December 2020

Relationship between expression of Bcl-2 genes and growth factors in ischemic acute renal failure in the rat

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12 December 2020

Reperfusion injury significantly impacts clinical outcome after pulmonary transplantation

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12 December 2020

Complement activation and inhibition in myocardial ischemia and reperfusion injury

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12 December 2020

Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia

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12 December 2020

Heme oxygenase-1 induction by hemin protects against gut ischemia/reperfusion injury

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12 December 2020

Ischaemia-reperfusion injury

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12 December 2020

Endothelins and the lung

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12 December 2020

Oxygen-dependent lipid peroxidation during lung ischemia

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12 December 2020

Peroxisome proliferator-activated receptor-alpha and atherosclerosis: from basic mechanisms to clinical implications

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12 December 2020

Mechanisms of renal repair and survival following acute injury

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12 December 2020

Hepatic release of endothelin-1 after warm ischemia. Reperfusion injury and its hemodynamic effect

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12 December 2020

Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure

1 reference

12 December 2020

Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity

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12 December 2020

Peroxisome proliferator-activated receptor-α regulates postischemic liver injury

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12 December 2020

The ultrastructure of "brain death". II. Electron microscopy of feline cortex after complete ischemia

1 reference

12 December 2020

Cardioprotection mediated by rosiglitazone, a peroxisome proliferator-activated receptor gamma ligand, in relation to nitric oxide

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12 December 2020

Kupffer cell-independent acute hepatocellular oxidative stress and decreased bile formation in post-cold-ischemic rat liver

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12 December 2020

Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro.

1 reference

12 December 2020

Leukocyte-derived metabolites of arachidonic acid in ischemia-induced myocardial injury

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12 December 2020

Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size

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12 December 2020

Reperfusion injury of the liver: role of mitochondria and protection by glutathione ester

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12 December 2020

A peroxisome proliferator-activated receptor-gamma agonist reduces infarct size in transient but not in permanent ischemia

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12 December 2020

Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia

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12 December 2020

Be fit or be sick: peroxisome proliferator-activated receptors are down the road

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12 December 2020

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium

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12 December 2020

Role for complement in mediating intestinal nitric oxide synthase-2 and superoxide dismutase expression

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12 December 2020

Anti-apoptotic effects of rosiglitazone in hypercholesterolemic rabbits subjected to myocardial ischemia and reperfusion

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12 December 2020

Interleukin 1 and tumor necrosis factor production as the initial stimulants of liver ischemia and reperfusion injury

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12 December 2020

The intracerebral application of the PPARgamma-ligand pioglitazone confers neuroprotection against focal ischaemia in the rat brain

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12 December 2020

Role of apoptosis in the pathogenesis of acute renal failure

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12 December 2020

Complement in the pathophysiology of human disease

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12 December 2020

Co-expression of endothelin-1 and vascular endothelial growth factor mediates increased vascular permeability in lung grafts before reperfusion

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12 December 2020

Interleukin-6 changes deformability of neutrophils and induces their sequestration in the lung

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12 December 2020

Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+

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12 December 2020

Endothelin-1 causes P-selectin-dependent leukocyte rolling and adhesion within rat mesenteric microvessels

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12 December 2020

Beneficial effects of extracellular glutathione against endotoxin-induced liver injury during ischemia and reperfusion.

1 reference

12 December 2020

The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion.

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12 December 2020

Role of nitric oxide in intestinal ischaemia-reperfusion injury studied using electron paramagnetic resonance

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12 December 2020

Prophylactic pharmacologic neuroprotection against focal cerebral ischemia

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12 December 2020

Protective effects of preischemic treatment with pioglitazone, a peroxisome proliferator-activated receptor-gamma ligand, on lung ischemia-reperfusion injury in rats

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12 December 2020

The cardioprotective effects of preconditioning with endotoxin, but not ischemia, are abolished by a peroxisome proliferator-activated receptor-gamma antagonist

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12 December 2020

Peroxisomal proliferation protects from beta-amyloid neurodegeneration

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12 December 2020

Ischemia/reperfusion injury

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12 December 2020

Contributions of ischemia and reperfusion to mucosal lesion formation

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12 December 2020

Peroxisome proliferator-activated receptors gamma ligands and ischemia and reperfusion injury

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12 December 2020

Cisplatin nephrotoxicity

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12 December 2020

Role of constitutive nitric oxide synthase and peroxynitrite production in a rat model of splanchnic artery occlusion shock

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12 December 2020

Chemokines — Chemotactic Cytokines That Mediate Inflammation

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12 December 2020

Adipogenic transcriptional regulation of hepatic stellate cells

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12 December 2020

Enzyme distribution along the nephron

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12 December 2020

Transcriptional effects of chronic Akt activation in the heart.

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12 December 2020

Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor gamma contributes to the antifibrotic activity of FXR ligands in rodent models of liver cirrhosis

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12 December 2020

Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia in rats

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12 December 2020

Effect of endothelin receptor antagonist on lung allograft apoptosis and NOSII expression

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12 December 2020

Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome

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12 December 2020

Peroxisome proliferator-activated receptor gamma suppresses proximal alpha1(I) collagen promoter via inhibition of p300-facilitated NF-I binding to DNA in hepatic stellate cells

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12 December 2020

Mechanisms of reperfusion injury after warm ischemia of the liver

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12 December 2020

Ischemia-induced interleukin-8 release after human heart transplantation. A potential role for endothelial cells

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12 December 2020

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

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12 December 2020

Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment.

1 reference

12 December 2020

Heparin-binding EGF-like growth factor downregulates expression of adhesion molecules and infiltration of inflammatory cells after intestinal ischemia/reperfusion injury

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12 December 2020

Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver

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12 December 2020

Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide

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12 December 2020

Effects of NF-kappa B inhibition on mesenteric ischemia-reperfusion injury

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12 December 2020

The role of neutrophils in myocardial ischemia-reperfusion injury

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12 December 2020

A specific peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligand, pioglitazone, ameliorates gastric mucosal damage induced by ischemia and reperfusion in rats

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12 December 2020

Endothelial injury and dysfunction: role in the extension phase of acute renal failure.

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12 December 2020

The chemical basis for the intolerance of the brain to anoxia

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12 December 2020

PPARgamma and atherosclerosis

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12 December 2020

Kupffer cell production of cytokine-induced neutrophil chemoattractant following ischemia/reperfusion injury in rats

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12 December 2020

Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643.

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12 December 2020

Altered endothelin receptor subtype expression in hepatic injury after ischemia/reperfusion

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12 December 2020

Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study

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12 December 2020

The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation

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12 December 2020

Oxidative stress and neutrophil activation--the two keystones of ischemia/reperfusion injury.

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12 December 2020

Anatomical distributions of four pharmacologically distinct 3H-L-glutamate binding sites

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12 December 2020

Oxygen-derived free radicals in postischemic tissue injury

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12 December 2020

The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis

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12 December 2020

Apoptosis of tubular epithelial cells in donor kidney biopsies predicts early renal allograft function

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12 December 2020

The role of fibric acids in atherosclerosis

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12 December 2020

Therapeutic roles of peroxisome proliferator-activated receptor agonists

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12 December 2020

Early renal ischemia, with or without reperfusion, activates NFkappaB and increases TNF-alpha bioactivity in the kidney

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12 December 2020

PPARdelta modulates lipopolysaccharide-induced TNFalpha inflammation signaling in cultured cardiomyocytes

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12 December 2020

Complement activation as a cause for primary graft failure in an isogeneic rat model of hypothermic lung preservation and transplantation

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12 December 2020

Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF.

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12 December 2020

NO-mediated vasodilation in the rat liver. Role of hepatocytes and liver endothelial cells

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12 December 2020

Role of fibric acid derivatives in the management of risk factors for coronary heart disease

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12 December 2020

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12 December 2020

Cardioprotective effects of rosiglitazone are associated with selective overexpression of type 2 angiotensin receptors and inhibition of p42/44 MAPK.

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells

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12 December 2020

Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion

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12 December 2020

Amelioration of lung reperfusion injury by L- and E- selectin blockade.

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12 December 2020

Current strategies in lung preservation

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12 December 2020

Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor alpha in mice

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12 December 2020

Cell death in human lung transplantation: apoptosis induction in human lungs during ischemia and after transplantation.

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12 December 2020

Protective effect of peroxisome proliferator activated receptor gamma agonists on diabetic and non-diabetic renal diseases

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12 December 2020

PPAR delta: an uncompletely known nuclear receptor

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12 December 2020

Endothelin-1 is involved in the pathogenesis of ischemia/reperfusion liver injury by hepatic microcirculatory disturbances

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12 December 2020

VEGF-A and -C but not -B mediate increased vascular permeability in preserved lung grafts

1 reference

12 December 2020

Suppression of intestinal ischemia-reperfusion injury by a specific peroxisome proliferator-activated receptor-gamma ligand, pioglitazone, in rats

1 reference

12 December 2020

Cloning and expression of a cDNA encoding an endothelin receptor

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12 December 2020

Prominent and sustained up-regulation of gp130-signaling cytokines and the chemokine MIP-2 in murine renal ischemia-reperfusion injury

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12 December 2020

Ionic changes in brain ischaemia and alterations produced by drugs

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12 December 2020

CD4(+) T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver

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12 December 2020

Morphological mechanisms for regulating blood flow through hepatic sinusoids

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12 December 2020

PPARgamma agonists exert antifibrotic effects in renal tubular cells exposed to high glucose

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12 December 2020

Complement and tumor necrosis factor-alpha contribute to Mac-1 (CD11b/CD18) up-regulation and systemic neutrophil activation during endotoxemia in vivo

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12 December 2020

Ischemia-reperfusion injury: role of oxygen-derived free radicals.

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12 December 2020

Endothelin-1 changes polymorphonuclear leukocytes' deformability and CD11b expression and promotes their retention in the lung

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12 December 2020

PPARs: therapeutic targets for metabolic disease

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12 December 2020

Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells.

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12 December 2020

Activation of peroxisome proliferator-activated receptor-alpha protects the heart from ischemia/reperfusion injury

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12 December 2020

Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets

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12 December 2020

The inflammatory response in myocardial infarction

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12 December 2020

Ischemia as an excitotoxic lesion: protection against hippocampal nerve cell loss by denervation

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12 December 2020

Cardioprotection from ischemia and reperfusion injury by an endothelin A-receptor antagonist in relation to nitric oxide production

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12 December 2020

Differential NADPH- versus NADH-dependent superoxide production by phagocyte-type endothelial cell NADPH oxidase

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12 December 2020

The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure.

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12 December 2020

Thiazolidinedione treatment inhibits bile duct proliferation and fibrosis in a rat model of chronic cholestasis

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12 December 2020

Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure

1 reference

12 December 2020

Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

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12 December 2020

The machinery of programmed cell death.

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12 December 2020

Chemokine involvement in hepatic ischemia/reperfusion injury in mice: Roles for macrophage inflammatory protein-2 and kupffer cells

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12 December 2020

Intracellular generation of reactive oxygen species during nonhypoxic lung ischemia

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12 December 2020

Evaluation of lung metabolism during successful twenty-four-hour canine lung preservation

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12 December 2020

Tumor necrosis factor in the heart.

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12 December 2020

ROLE of endogenous peroxisome proliferator-activated receptor-alpha (PPAR-alpha) ligands in the development of gut ischemia and reperfusion in mice

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12 December 2020

N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia

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12 December 2020

Endotoxemia and remote organ injury following intestinal reperfusion

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12 December 2020

1 reference

12 December 2020

PPAR signaling in the control of cardiac energy metabolism

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12 December 2020

PPAR-alpha ligand ameliorates acute renal failure by reducing cisplatin-induced increased expression of renal endonuclease G

1 reference

12 December 2020

Cirrhosis: new research provides a basis for rational and targeted treatments

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12 December 2020

WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock

1 reference

12 December 2020

Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo

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12 December 2020

Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury

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12 December 2020

Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury

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12 December 2020

Rosiglitazone, a peroxisome proliferator-activated receptor-gamma, inhibits the Jun NH(2)-terminal kinase/activating protein 1 pathway and protects the heart from ischemia/reperfusion injury

1 reference

12 December 2020

Activation of cerebral peroxisome proliferator-activated receptors gamma promotes neuroprotection by attenuation of neuronal cyclooxygenase-2 overexpression after focal cerebral ischemia in rats

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12 December 2020

Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.

1 reference

12 December 2020

Limitation of infarct size and attenuation of myeloperoxidase activity by an endothelin A receptor antagonist following ischaemia and reperfusion

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12 December 2020

Role of induced nitric oxide in the initiation of the inflammatory response after postischemic injury

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12 December 2020

The early release of interleukin-2, tumor necrosis factor-alpha and interferon-gamma after ischemia reperfusion injury in the lung allograft

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12 December 2020

The role of adhesion molecules and T cells in ischemic renal injury

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12 December 2020

Modulation of chemokine expression during ischemia/reperfusion in transgenic mice overproducing human glutathione peroxidases

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12 December 2020

Mechanisms of ischemic cerebral injury

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12 December 2020

Effect of classic preconditioning on the gene expression pattern of rat hearts: a DNA microarray study

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12 December 2020

10.1007/S00210-007-0141-2

Identifiers

DOI

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16 August 2017

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