Netrins: beyond the brain (Q36759032)

16 August 2017

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title

Netrins: beyond the brain (English)

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16 August 2017

Vincenzo Cirulli

1

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16 August 2017

Mayra Yebra

series ordinal

2

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16 August 2017

publication date

14 March 2007

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Nature Reviews Molecular Cell Biology

16 August 2017

published in

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16 August 2017

volume

8

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16 August 2017

issue

4

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16 August 2017

page(s)

296-306

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Cell-matrix interactions and cell adhesion during development

16 August 2017

cites work

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Extracellular matrix/growth factor interactions

31 March 2020

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The molecular biology of axon guidance

31 March 2020

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The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.

31 March 2020

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Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

31 March 2020

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The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

31 March 2020

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UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans

31 March 2020

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Guidance cues at the Drosophila CNS midline: identification and characterization of two Drosophila Netrin/UNC-6 homologs

31 March 2020

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Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons.

31 March 2020

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Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system

31 March 2020

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Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC.

31 March 2020

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Axon Tracts Correlate withNetrin-1aExpression in the Zebrafish Embryo

31 March 2020

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Expression and regulation of a netrin homologue in the zebrafish embryo.

31 March 2020

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The NTN2L gene encoding a novel human netrin maps to the autosomal dominant polycystic kidney disease region on chromosome 16p13.3

31 March 2020

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Identification and expression of mouse netrin-4.

31 March 2020

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A novel member of the netrin family, beta-netrin, shares homology with the beta chain of laminin: identification, expression, and functional characterization

31 March 2020

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Complementary expression and neurite outgrowth activity of netrin-G subfamily members

31 March 2020

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Strong expression of NETRIN-G2 in the monkey claustrum

31 March 2020

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Human netrin-G1 isoforms show evidence of differential expression

31 March 2020

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A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia

31 March 2020

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Netrin 1-mediated chemoattraction regulates the migratory pathway of LHRH neurons

31 March 2020

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Netrins and DCC in the guidance of migrating neural crest-derived cells in the developing bowel and pancreas

31 March 2020

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Deleted in colorectal carcinoma and differentially expressed integrins mediate the directional migration of neural precursors in the rostral migratory stream.

31 March 2020

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Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation

31 March 2020

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Netrin-1 expression in fetal and regenerating rat pancreas and its effect on the migration of human pancreatic duct and porcine islet precursor cells

31 March 2020

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Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration

31 March 2020

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Expression of Netrin-1 and its two receptors DCC and UNC5H2 in the developing mouse lung.

31 March 2020

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Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis

31 March 2020

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Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis

31 March 2020

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The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system

31 March 2020

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The axonal attractant Netrin-1 is an angiogenic factor.

31 March 2020

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Common mechanisms of nerve and blood vessel wiring

31 March 2020

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Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism

31 March 2020

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Netrins promote developmental and therapeutic angiogenesis.

31 March 2020

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Netrin-1 inhibits leukocyte migration in vitro and in vivo.

31 March 2020

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Netrins and neogenin promote myotube formation

31 March 2020

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Assembly and tissue functions of early embryonic laminins and netrins.

31 March 2020

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Glycosaminoglycan-binding properties and secondary structure of the C-terminus of netrin-1

31 March 2020

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Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

31 March 2020

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The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

31 March 2020

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Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer

31 March 2020

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Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

31 March 2020

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Identification of a chromosome 18q gene that is altered in colorectal cancers

31 March 2020

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The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment

31 March 2020

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Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor

31 March 2020

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Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation

31 March 2020

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The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis

31 March 2020

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The Netrin family of guidance factors: emphasis on Netrin-1 signalling

31 March 2020

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The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

31 March 2020

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A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion

31 March 2020

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Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1.

31 March 2020

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The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM.

31 March 2020

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31 March 2020

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Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation

31 March 2020

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Focal adhesion kinase in netrin-1 signaling

31 March 2020

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Activation of FAK and Src are receptor-proximal events required for netrin signaling

31 March 2020

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Calcium signalling in the guidance of nerve growth by netrin-1.

31 March 2020

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cAMP-dependent growth cone guidance by netrin-1.

31 March 2020

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Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning.

31 March 2020

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31 March 2020

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Neurobiology: New Connections between Integrins and Axon Guidance

31 March 2020

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Netrin-integrin signaling in epithelial morphogenesis, axon guidance and vascular patterning

31 March 2020

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Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.

31 March 2020

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Netrin-1: when a neuronal guidance cue turns out to be a regulator of tumorigenesis

31 March 2020

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The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation

31 March 2020

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The dependence receptor DCC requires lipid raft localization for cell death signaling

31 March 2020

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The region-specific activities of lipid rafts during axon growth and guidance

31 March 2020

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DCC association with lipid rafts is required for netrin-1-mediated axon guidance

31 March 2020

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p53RDL1 regulates p53-dependent apoptosis

31 March 2020

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Netrin-1 controls colorectal tumorigenesis by regulating apoptosis

31 March 2020

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A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

31 March 2020

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Intercellular signals regulating pancreas development and function

31 March 2020

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Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells

31 March 2020

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The alpha 6 beta 4 integrin and epithelial cell migration

31 March 2020

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Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development

31 March 2020

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A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth

31 March 2020

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Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development

31 March 2020

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Sonic hedgehog regulates branching morphogenesis in the mammalian lung

31 March 2020

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Distribution of laminin 5, integrin receptors, and branching morphogenesis during human fetal lung development

31 March 2020

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Key stages in mammary gland development: the mammary end bud as a motile organ.

31 March 2020

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Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes

31 March 2020

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Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis

31 March 2020

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Guidance of vascular and neural network formation

31 March 2020

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Cell migration: integrating signals from front to back

31 March 2020

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Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions

31 March 2020

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Cell contact-dependent activation of alpha3beta1 integrin modulates endothelial cell responses to thrombospondin-1

31 March 2020

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NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin

31 March 2020

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Receptor functions for the integrin VLA-3: fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations

31 March 2020

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Upregulation of the netrin receptor (DCC) gene during activation of b lymphocytes and modulation by interleukins

31 March 2020

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Axon guidance by diffusible chemoattractants: a gradient of netrin protein in the developing spinal cord.

31 March 2020

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Regulation of human neural precursor cells by laminin and integrins

31 March 2020

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Specific beta1 integrins mediate adhesion, migration, and differentiation of neural progenitors derived from the embryonic striatum

31 March 2020

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Essential role of alpha 6 integrins in cortical and retinal lamination

31 March 2020

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Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function

31 March 2020

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Sema4D induces angiogenesis through Met recruitment by Plexin B1

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRM2142

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16 August 2017

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