The small molecule TGF-β signaling inhibitor SM16 synergizes with agonistic OX40 antibody to suppress established mammary tumors and reduce spontaneous metastasis (Q36677504)

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scientific article published on 5 October 2011

Language	Label	Description	Also known as
English	The small molecule TGF-β signaling inhibitor SM16 synergizes with agonistic OX40 antibody to suppress established mammary tumors and reduce spontaneous metastasis	scientific article published on 5 October 2011

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

The small molecule TGF-β signaling inhibitor SM16 synergizes with agonistic OX40 antibody to suppress established mammary tumors and reduce spontaneous metastasis (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Kendra Garrison

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Tobias Hahn

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Wen-Cherng Lee

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Leona E Ling

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Andrew D Weinberg

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Emmanuel T Akporiaye

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

publication date

5 October 2011

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Cancer Immunology, Immunotherapy

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

61

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

511-521

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Use of anti-cancer drugs, mitocans, to enhance the immune responses against tumors.

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Toll-Like Receptors, Tissue Injury, and Tumourigenesis

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1 reference

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Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

1 reference

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Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

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30 September 2017

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

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30 September 2017

Induction of anti-mammary cancer immunity by engaging the OX-40 receptor in vivo

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30 September 2017

New approaches to antibody therapy

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Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

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Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer

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A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection.

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Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses

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1 reference

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OX40 (CD134) engagement drives differentiation of CD4+ T cells to effector cells

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Functional characterization of OX40 expressed on human CD8+ T cells

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Identifiers

10.1007/S00262-011-1119-Y

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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