Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction (Q36560578)

14 August 2017

Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction (English)

1 reference

14 August 2017

Yinan Hua

1

1 reference

14 August 2017

Yingmei Zhang

2

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14 August 2017

Julia Dolence

3

1 reference

14 August 2017

Guo-Ping Shi

4

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14 August 2017

Jun Ren

5

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14 August 2017

Sreejayan Nair

6

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14 August 2017

language of work or name

English

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publication date

15 October 2012

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14 August 2017

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14 August 2017

62

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14 August 2017

2

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14 August 2017

498-509

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

14 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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AKT signalling in the failing heart

30 September 2017

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Cysteinyl cathepsins and mast cell proteases in the pathogenesis and therapeutics of cardiovascular diseases

30 September 2017

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RETRACTED: Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity-induced myocardial contractile dysfunction

30 September 2017

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Specialized roles for cysteine cathepsins in health and disease.

30 September 2017

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Obesogenic high fat western diet induces oxidative stress and apoptosis in rat heart

30 September 2017

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Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction.

30 September 2017

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Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice

30 September 2017

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Apoptosis in hypertensive heart disease: a clinical approach

30 September 2017

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Cathepsin-regulated apoptosis

30 September 2017

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Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice

30 September 2017

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Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Ph

30 September 2017

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Cardiac remodeling and failure From molecules to man (Part II).

30 September 2017

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Increased expression of elastolytic cysteine proteases, cathepsins S and K, in the neointima of balloon-injured rat carotid arteries

30 September 2017

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Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates

30 September 2017

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Cardiac-specific overexpression of a superinhibitory pentameric phospholamban mutant enhances inhibition of cardiac function in vivo

30 September 2017

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Lipotoxic heart disease in obese rats: implications for human obesity

30 September 2017

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Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells

30 September 2017

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30 September 2017

Obesity and the heart

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Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling

30 September 2017

1 reference

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Cell type-specific functions of the lysosomal protease cathepsin L in the heart

21 September 2018

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Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy

21 September 2018

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Mice lacking cathepsin K maintain bone remodeling but develop bone fragility despite high bone mass

21 September 2018

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Increased expression of elastolytic cathepsins S, K, and V and their inhibitor cystatin C in stenotic aortic valves.

21 September 2018

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Targeted deletion of matrix metalloproteinase 2 ameliorates myocardial remodeling in mice with chronic pressure overload.

21 September 2018

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Cardiovascular mortality in overweight subjects: the key role of associated risk factors

21 September 2018

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Increased serum cathepsin S in patients with atherosclerosis and diabetes

21 September 2018

1 reference

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A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

21 September 2018

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Akt signaling mediates postnatal heart growth in response to insulin and nutritional status

21 September 2018

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Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart.

21 September 2018

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Echocardiographic abnormalities in normotensive obese patients: relationship with visceral fat.

21 September 2018

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Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554365

Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis

4 December 2018

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Clinical implications of apoptosis in hypertensive heart disease

4 December 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554365

Cardiac-specific overexpression of a high Ca2+ affinity mutant of SERCA2a attenuates in vivo pressure overload cardiac hypertrophy

4 December 2018

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12 December 2020

The impact of obesity on left ventricular mass and geometry. The Framingham Heart Study

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12 December 2020

Enhanced myocardial cathepsin B expression in patients with dilated cardiomyopathy

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12 December 2020

Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association

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12 December 2020

Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure

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12 December 2020

Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis

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12 December 2020

Physiology. An integrative view of obesity

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12 December 2020

Identifiers

DOI

10.2337/DB12-0350

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

23069627

1 reference