Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor (Q36536820)

14 August 2017

Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor (English)

1 reference

14 August 2017

Elling CE

1

1 reference

14 August 2017

Thirstrup K

series ordinal

2

1 reference

14 August 2017

Holst B

series ordinal

3

1 reference

14 August 2017

Schwartz TW

series ordinal

4

1 reference

14 August 2017

language of work or name

English

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publication date

1 October 1999

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Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

1 reference

14 August 2017

96

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14 August 2017

22

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14 August 2017

12322-12327

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Design of potent selective zinc-mediated serine protease inhibitors

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Structure and function in rhodopsin: Rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Connectivity and orientation of the seven helical bundle in the tachykinin NK-1 receptor probed by zinc site engineering

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Distance determination in proteins using designed metal ion binding sites and site-directed spin labeling: application to the lactose permease of Escherichia coli

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

A method for distance determination in proteins using a designed metal ion binding site and site-directed spin labeling: evaluation with T4 lysozyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

The probable arrangement of the helices in G protein-coupled receptors.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Structure and function of G protein-coupled receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Locating ligand-binding sites in 7TM receptors by protein engineering.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Pindolol--the pharmacology of a partial agonist

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Structural Aspects of Metal Liganding to Functional Groups in Proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

A point mutation in the seventh hydrophobic domain of the alpha 2 adrenergic receptor increases its affinity for a family of beta receptor antagonists

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Allele-specific activation of genetically engineered receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

How receptors talk to trimeric G proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

G-protein diseases furnish a model for the turn-on switch

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Rhodopsin: A Prototypical G Protein-Coupled Receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors 1 1Edited by R. Huber

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Effect of carboxylic acid side chains on the absorption maximum of visual pigments

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Conversion of the human 5-HT1D beta serotonin receptor to the rat 5-HT1B ligand-binding phenotype by Thr355Asn site directed mutagenesis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Identification of a single amino acid residue responsible for the binding of a class of beta-adrenergic receptor antagonists to 5-hydroxytryptamine1A receptors

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22915

Construction of a high affinity zinc switch in the kappa-opioid receptor.

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

Engineering of metal-ion sites as distance constraints in structural and functional analysis of 7TM receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

The prediction and characterization of metal binding sites in proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 1. Proximity of helix VII (Asp237 and Asp240) with helices X (Lys319) and XI (Lys358).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

Arrangement of rhodopsin transmembrane α-helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

Projection structure of rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

Combined biophysical and biochemical information confirms arrangement of transmembrane helices visible from the three-dimensional map of frog rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

Water and peptide backbone structure in the active center of bovine rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12322

21 January 2018

Identifiers

DOI

10.1073/PNAS.96.22.12322

1 reference

14 August 2017

0 references

1 reference

14 August 2017

PubMed publication ID

10535920

1 reference