Dynamic imaging of the immune system: progress, pitfalls and promise (Q36518928)

14 August 2017

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title

Dynamic imaging of the immune system: progress, pitfalls and promise (English)

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14 August 2017

Michael L Dustin

3

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Michel C. Nussenzweig

series ordinal

4

object named as

Michel C Nussenzweig

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14 August 2017

1

Ronald N Germain

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14 August 2017

Mark J Miller

2

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14 August 2017

publication date

1 July 2006

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Nature Reviews Immunology

14 August 2017

published in

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14 August 2017

volume

6

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14 August 2017

issue

7

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14 August 2017

page(s)

497-507

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Approaching the asymptote? Evolution and revolution in immunology

14 August 2017

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Intravital microscopy comparing T lymphocyte trafficking to the spleen and the mesenteric lymph node

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Lymphocyte trafficking and regional immunity.

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In vivo imaging of leukocyte trafficking in blood vessels and tissues

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Homing and cellular traffic in lymph nodes

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Dendritic cells and the control of immunity

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Close encounters of different kinds: dendritic cells and NK cells take centre stage

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Dendritic cells as sensors of infection.

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Shaping the immune response to parasites: role of dendritic cells

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In vivo imaging of lymphocyte trafficking

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Derivation and diversification of monoclonal antibodies

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Monoclonal antibodies and the FACS: complementary tools for immunobiology and medicine

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Two-photon laser scanning fluorescence microscopy

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An evaluation of confocal versus conventional imaging of biological structures by fluorescence light microscopy

31 March 2020

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Imaging immune cell interactions and functions: SMACs and the Immunological Synapse

31 March 2020

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Three-dimensional segregation of supramolecular activation clusters in T cells

31 March 2020

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Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

31 March 2020

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The immunological synapse: a molecular machine controlling T cell activation

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Molecular Mechanisms of Lymphocyte Homing to Peripheral Lymph Nodes

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Dynamic imaging of T cell-dendritic cell interactions in lymph nodes

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Two-photon imaging of lymphocyte motility and antigen response in intact lymph node

31 March 2020

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Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes

31 March 2020

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Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy

31 March 2020

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Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes

31 March 2020

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T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

31 March 2020

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T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node

31 March 2020

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Visualizing dendritic cell networks in vivo

31 March 2020

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Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity

31 March 2020

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A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo

31 March 2020

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Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo

31 March 2020

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Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells

31 March 2020

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Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

31 March 2020

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Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

31 March 2020

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Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids

31 March 2020

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An extended vision for dynamic high-resolution intravital immune imaging.

31 March 2020

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Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells

31 March 2020

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Confocal fluorescent intravital microscopy of the murine spleen.

31 March 2020

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Two-photon imaging in intact lymphoid tissue.

31 March 2020

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In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance.

31 March 2020

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Two-photon analysis of calcium signals in T lymphocytes of intact lamina propria from human intestine.

31 March 2020

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Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy.

31 March 2020

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Calcium oscillations regulate thymocyte motility during positive selection in the three-dimensional thymic environment

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Directed migration of positively selected thymocytes visualized in real time

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Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.

31 March 2020

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Imaging ocular immune responses by intravital microscopy.

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Direct impact of T cells on neurons revealed by two-photon microscopy in living brain tissue.

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Molecular imaging applications for immunology

31 March 2020

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31 March 2020

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A stochastic view of lymphocyte motility and trafficking within the lymph node

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Visualizing the first 50 hr of the primary immune response to a soluble antigen.

31 March 2020

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Close encounters of the first and second kind: T-DC and T-B interactions in the lymph node

31 March 2020

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Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction.

31 March 2020

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Dynamic behavior of T cells and thymocytes in lymphoid organs as revealed by two-photon microscopy.

31 March 2020

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Two-photon tissue imaging: seeing the immune system in a fresh light

31 March 2020

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Real-time imaging of lymphocytes in vivo

31 March 2020

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In vivo imaging approaches in animal models of rheumatoid arthritis

31 March 2020

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Visualizing thymocyte motility using 2-photon microscopy.

31 March 2020

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Thymopoiesis in 4 dimensions

31 March 2020

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Real-time measurement of signaling and motility during T cell development in the thymus

31 March 2020

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Creating new fluorescent probes for cell biology.

31 March 2020

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

31 March 2020

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Recombineering: a powerful new tool for mouse functional genomics

31 March 2020

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Genetic manipulation of hematopoietic stem cells

31 March 2020

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Innovations in the imaging of brain functions using fluorescent proteins

31 March 2020

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Building and breeding molecules to spy on cells and tumors

31 March 2020

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In vivo molecular and cellular imaging with quantum dots

31 March 2020

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Anesthesia-associated depression in lymphocyte traffic and its modulation

31 March 2020

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Two-photon excitation fluorescence microscopy

31 March 2020

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Imaging cells and extracellular matrix in vivo by using second-harmonic generation and two-photon excited fluorescence

31 March 2020

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Advancing molecular therapies through in vivo bioluminescent imaging

31 March 2020

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Digitizing life at the level of the cell: high-performance laser-scanning microscopy and image analysis for in toto imaging of development

31 March 2020

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31 March 2020

Chirped optical pulses

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Compensation of spatial and temporal dispersion for acousto-optic multiphoton laser-scanning microscopy

31 March 2020

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Construction of a two-photon microscope for video-rate Ca(2+) imaging

31 March 2020

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Video-rate scanning two-photon excitation fluorescence microscopy and ratio imaging with cameleons

31 March 2020

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Two-photon microscopy in brain tissue: parameters influencing the imaging depth.

31 March 2020

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Deep tissue two-photon microscopy

31 March 2020

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Two-photon imaging to a depth of 1000 microm in living brains by use of a Ti:Al2O3 regenerative amplifier

31 March 2020

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Thirty-six views of T-cell recognition

31 March 2020

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In vivo multiphoton microscopy of deep brain tissue

31 March 2020

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Two-photon fluorescence endoscopy with a micro-optic scanning head

31 March 2020

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Miniaturized two-photon microscope based on a flexible coherent fiber bundle and a gradient-index lens objective

31 March 2020

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In vivo mammalian brain imaging using one- and two-photon fluorescence microendoscopy

31 March 2020

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Fiber-optic fluorescence imaging

31 March 2020

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Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoprotein

31 March 2020

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Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation

31 March 2020

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Advances in fluorescence imaging with quantum dot bio-probes.

31 March 2020

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Noninvasive measurement of microvascular and interstitial oxygen profiles in a human tumor in SCID mice

31 March 2020

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Nonlinear structured-illumination microscopy: wide-field fluorescence imaging with theoretically unlimited resolution

31 March 2020

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Photostability of a fluorescent marker under pulsed excited-state depletion through stimulated emission

31 March 2020

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Achieving molecular selectivity in imaging using multiphoton Raman spectroscopy techniques

31 March 2020

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High efficiency beam splitter for multifocal multiphoton microscopy

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1884

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14 August 2017

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