Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy (Q36511003)

14 August 2017

Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy (English)

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14 August 2017

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Lori A Walker

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author name string

E Douglas Lewandowski

1

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14 August 2017

Susan K Fischer

2

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14 August 2017

Matthew Fasano

3

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14 August 2017

Natasha H Banke

4

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14 August 2017

Alda Huqi

6

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14 August 2017

Xuerong Wang

7

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14 August 2017

Gary D Lopaschuk

8

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14 August 2017

J Michael O'Donnell

9

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14 August 2017

14 September 2012

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14 August 2017

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14 August 2017

112

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14 August 2017

1

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14 August 2017

57-65

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Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Energy metabolism in heart failure and remodelling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

The absence of endogenous lipid oxidation in early stage heart failure exposes limits in lipid storage and turnover

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Malonyl-CoA decarboxylase (MCD) is differentially regulated in subcellular compartments by 5'AMP-activated protein kinase (AMPK). Studies using H9c2 cells overexpressing MCD and AMPK by adenoviral gene transfer technique

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Expression of novel isoforms of carnitine palmitoyltransferase I (CPT-1) generated by alternative splicing of the CPT-ibeta gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Change in expression of heart carnitine palmitoyltransferase I isoforms with electrical stimulation of cultured rat neonatal cardiac myocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Bioenergetic abnormalities associated with severe left ventricular hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Rat heart expresses two forms of mitochondrial carnitine palmitoyltransferase I. The minor component is identical to the liver enzyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Myocardial oxygenation at high workstates in hearts with left ventricular hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Acetyl-CoA carboxylase involvement in the rapid maturation of fatty acid oxidation in the newborn rabbit heart.

28 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Evaluation of carbon flux and substrate selection through alternate pathways involving the citric acid cycle of the heart by 13C NMR spectroscopy.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Analysis of acyl-coenzyme A esters in biological samples

28 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Interrelation between long-chain fatty acid oxidation rate and carnitine palmitoyltransferase 1 activity with different isoforms in rat tissues

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Efficient, cardiac-specific adenoviral gene transfer in rat heart by isolated retrograde perfusion in vivo

21 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Mechanisms for increased glycolysis in the hypertrophied rat heart

21 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Metabolic gene expression in fetal and failing human heart

21 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

PKC-beta is not necessary for cardiac hypertrophy

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537878

Maturation of fatty acid and carbohydrate metabolism in the newborn heart

21 September 2018

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12 December 2020

Myocardial oxygenation during high work states in hearts with postinfarction remodeling

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12 December 2020

Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts

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12 December 2020

Intracerebroventricular leptin administration differentially alters cardiac energy metabolism in mice fed a low-fat and high-fat diet

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12 December 2020

Post-translational modifications, a key process in CD36 function: lessons from the spontaneously hypertensive rat heart

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12 December 2020

The fascinating and elusive life of cardiac fatty acids

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12 December 2020

Glycolysis is predominant source of myocardial ATP production immediately after birth

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12 December 2020

Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart

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12 December 2020

Kinetic Properties of Carnitine Palmitoyltransferase I in Cultured Neonatal Rat Cardiac Myocytes

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12 December 2020

Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts

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12 December 2020

Mitochondrial carnitine palmitoyltransferase I isoform switching in the developing rat heart

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12 December 2020

Fatty acid oxidation enzyme gene expression is downregulated in the failing heart

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12 December 2020

Upregulation of 5'-AMP-activated protein kinase is responsible for the increase in myocardial fatty acid oxidation rates following birth in the newborn rabbit

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12 December 2020

Altered Metabolite Exchange Between Subcellular Compartments in Intact Postischemic Rabbit Hearts

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12 December 2020

Failure to Maintain a Low ADP Concentration Impairs Diastolic Function in Hypertrophied Rat Hearts

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12 December 2020

Dehydrogenase regulation of metabolite oxidation and efflux from mitochondria in intact hearts

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12 December 2020

Characterization of cardiac malonyl-CoA decarboxylase and its putative role in regulating fatty acid oxidation

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12 December 2020

10.1161/CIRCRESAHA.112.274456

Identifiers

DOI

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14 August 2017

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14 August 2017

PubMed publication ID

22982985

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