Carbohydrate recognition by the antiviral lectin cyanovirin-N. (Q36492955)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23057413%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Carbohydrate recognition by the antiviral lectin cyanovirin-N (English)

1 reference

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10 March 2020

2

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10 March 2020

author name string

Yukiji K Fujimoto

series ordinal

1

1 reference

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10 March 2020

language of work or name

English

0 references

publication date

20 November 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23057413%20AND%20SRC:MED&resulttype=core&format=json

Journal of the American Chemical Society

10 March 2020

published in

1 reference

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10 March 2020

volume

134

1 reference

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10 March 2020

issue

48

1 reference

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10 March 2020

page(s)

19639-19651

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23057413%20AND%20SRC:MED&resulttype=core&format=json

All-atom empirical potential for molecular modeling and dynamics studies of proteins

10 March 2020

cites work

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Rational and computational design of stabilized variants of cyanovirin-N that retain affinity and specificity for glycan ligands.

30 September 2017

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Incorporation of the HIV-1 Microbicide Cyanovirin-N in a Food Product

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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A sugar binding protein cyanovirin-N blocks herpes simplex virus type-1 entry and cell fusion

30 September 2017

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30 September 2017

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Computational models explain the oligosaccharide specificity of cyanovirin-N.

30 September 2017

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Solution and Crystal Structures of a Sugar Binding Site Mutant of Cyanovirin-N: No Evidence of Domain Swapping

30 September 2017

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Treatment of influenza A (H1N1) virus infections in mice and ferrets with cyanovirin-N.

30 September 2017

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The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity

30 September 2017

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Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission

30 September 2017

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High-mannose-specific deglycosylation of HIV-1 gp120 induced by resistance to cyanovirin-N and the impact on antibody neutralization

30 September 2017

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A monovalent mutant of cyanovirin-N provides insight into the role of multiple interactions with gp120 for antiviral activity

30 September 2017

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Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy

30 September 2017

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Exploiting the defensive sugars of HIV-1 for drug and vaccine design

30 September 2017

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Microbicides: a new frontier in HIV prevention

30 September 2017

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Computational redesign of endonuclease DNA binding and cleavage specificity

30 September 2017

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Scalable molecular dynamics with NAMD

30 September 2017

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Flipping the switch from monomeric to dimeric CV-N has little effect on antiviral activity

30 September 2017

1 reference

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

30 September 2017

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Computational design of receptor and sensor proteins with novel functions

30 September 2017

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Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus

30 September 2017

1 reference

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Site-specific discrimination by cyanovirin-N for alpha-linked trisaccharides comprising the three arms of Man(8) and Man(9).

30 September 2017

1 reference

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Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides

30 September 2017

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The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures

30 September 2017

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Solution structure of a cyanovirin-N:Man alpha 1-2Man alpha complex: structural basis for high-affinity carbohydrate-mediated binding to gp120

30 September 2017

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The potent anti-HIV protein cyanovirin-N contains two novel carbohydrate binding sites that selectively bind to Man(8) D1D3 and Man(9) with nanomolar affinity: implications for binding to the HIV envelope protein gp120.

30 September 2017

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Binding free energies and free energy components from molecular dynamics and Poisson-Boltzmann calculations. Application to amino acid recognition by aspartyl-tRNA synthetase

30 September 2017

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Multiple antiviral activities of cyanovirin-N: blocking of human immunodeficiency virus type 1 gp120 interaction with CD4 and coreceptor and inhibition of diverse enveloped viruses

30 September 2017

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Electrostatic interactions in the GCN4 leucine zipper: substantial contributions arise from intramolecular interactions enhanced on binding

30 September 2017

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Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping

30 September 2017

1 reference

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Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120.

30 September 2017

1 reference

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Solution structure of cyanovirin-N, a potent HIV-inactivating protein

30 September 2017

1 reference

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De Novo Protein Design: Fully Automated Sequence Selection

30 September 2017

1 reference

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Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development

30 September 2017

1 reference

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Role of envelope glycoprotein carbohydrate in human immunodeficiency virus (HIV) infectivity and virus-induced cell fusion

30 September 2017

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Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells

30 September 2017

1 reference

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Rational design of new binding specificity by simultaneous mutagenesis of calmodulin and a target peptide

30 September 2017

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A role for carbohydrates in immune evasion in AIDS.

28 June 2018

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Energetic decomposition with the generalized-born and Poisson-Boltzmann solvent models: lessons from association of G-protein components.

28 June 2018

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Optimized parameters for continuum solvation calculations with carbohydrates

21 September 2018

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Binding of antifusion peptides with HIVgp41 from molecular dynamics simulations: quantitative correlation with experiment

21 September 2018

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Design of improved protein inhibitors of HIV-1 cell entry: Optimization of electrostatic interactions at the binding interface.

21 September 2018

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Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

21 September 2018

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Converging free energy estimates: MM-PB(GB)SA studies on the protein-protein complex Ras-Raf.

21 September 2018

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Carbohydrate solution simulations: producing a force field with experimentally consistent primary alcohol rotational frequencies and populations

21 September 2018

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Rational cytokine design for increased lifetime and enhanced potency using pH-activated "histidine switching".

21 September 2018

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Engineering an obligate domain-swapped dimer of cyanovirin-N with enhanced anti-HIV activity.

21 September 2018

1 reference

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Implicit solvent simulations of DNA and DNA-protein complexes: agreement with explicit solvent vs experiment

21 September 2018

1 reference

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Carbohydrate-binding Agents Cause Deletions of Highly Conserved Glycosylation Sites in HIV GP120

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531799

Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89.6P in macaques

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23057413

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protein stabilization by removal of unsatisfied polar groups: computational approaches and experimental tests

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23057413

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JA305755B

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23057413%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23057413%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

23057413

1 reference