Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter. (Q36451833)

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12 February 2020

title

Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter (English)

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12 February 2020

4

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12 February 2020

Natascha Hermann-Kleiter

1

object named as

Natascha Hermann-Kleiter

1 reference

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12 February 2020

author name string

Marlies Meisel

2

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12 February 2020

Friedrich Fresser

3

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12 February 2020

Mathias Müller

5

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12 February 2020

Lukas Roth

6

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12 February 2020

Andreas Katopodis

7

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12 February 2020

Gottfried Baier

8

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12 February 2020

publication date

24 August 2012

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12 February 2020

published in

Journal of Autoimmunity

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12 February 2020

volume

39

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12 February 2020

issue

4

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12 February 2020

page(s)

428-440

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Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2.

12 February 2020

cites work

1 reference

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1,25-Dihydroxyvitamin D3Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A

30 September 2017

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Transcriptional regulation of the Th17 immune response by IKKα

30 September 2017

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Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

30 September 2017

1 reference

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Fate mapping of IL-17-producing T cells in inflammatory responses

30 September 2017

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Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation

30 September 2017

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Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3.

30 September 2017

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

30 September 2017

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Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis

30 September 2017

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Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells

30 September 2017

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T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis

30 September 2017

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Chromatin immunoprecipitation (ChIP).

30 September 2017

1 reference

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Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase

30 September 2017

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The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity

30 September 2017

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Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines

30 September 2017

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The AP-1 transcription factor Batf controls T(H)17 differentiation

30 September 2017

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Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

30 September 2017

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Transcriptional regulatory networks in Th17 cell differentiation

30 September 2017

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Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

30 September 2017

1 reference

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Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

30 September 2017

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30 September 2017

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Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells

30 September 2017

1 reference

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IL-21 signaling is critical for the development of type I diabetes in the NOD mouse

30 September 2017

1 reference

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The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity

30 September 2017

1 reference

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Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression

30 September 2017

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The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer

30 September 2017

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Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat

30 September 2017

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30 September 2017

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TH17 cells in development: an updated view of their molecular identity and genetic programming

30 September 2017

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TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

30 September 2017

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

30 September 2017

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Ets-1 is a negative regulator of Th17 differentiation

30 September 2017

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Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

30 September 2017

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30 September 2017

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

30 September 2017

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Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

30 September 2017

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NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression

30 September 2017

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T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype.

30 September 2017

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PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation

28 June 2018

1 reference

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TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cells

21 September 2018

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Crucial role for nuclear factor of activated T cells in T cell receptor-mediated regulation of human interleukin-17.

21 September 2018

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Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their Expansion

21 September 2018

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[Foxp3-transfected CD4+ CD25- T cells suppress function of dendritic cells]

4 December 2018

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12 December 2020

Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation

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12 December 2020

T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity

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12 December 2020

[The progresses of research on SOCS family in the central nervous system]

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12 December 2020

Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin

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12 December 2020

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

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12 December 2020

10.1016/J.JAUT.2012.07.007

Identifiers

DOI

1 reference

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12 February 2020

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12 February 2020

PubMed publication ID

22921335

1 reference

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