MerTK is required for apoptotic cell-induced T cell tolerance (Q36446918)

14 August 2017

MerTK is required for apoptotic cell-induced T cell tolerance (English)

1 reference

14 August 2017

0 references

11

Roland Tisch

1 reference

14 August 2017

10

Bo Wang

1 reference

14 August 2017

1

Mark A Wallet

1 reference

14 August 2017

7

Clayton E Mathews

1 reference

14 August 2017

8

H Shelton Earp

1 reference

14 August 2017

9

Glenn Matsushima

1 reference

14 August 2017

Pradip Sen

2

1 reference

14 August 2017

Rafael R Flores

3

1 reference

14 August 2017

Yaming Wang

4

1 reference

14 August 2017

Zuoan Yi

5

1 reference

14 August 2017

Yingsu Huang

6

1 reference

14 August 2017

language of work or name

English

0 references

publication date

14 January 2008

1 reference

Journal of Experimental Medicine

14 August 2017

1 reference

14 August 2017

205

1 reference

14 August 2017

1

1 reference

14 August 2017

219-232

1 reference

Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Twist mediates suppression of inflammation by type I IFNs and Axl

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Phosphatidylserine recognition by phagocytes: a view to a kill

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Immunoregulation of dendritic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Both protein S and Gas6 stimulate outer segment phagocytosis by cultured rat retinal pigment epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Defects in the disposal of dying cells lead to autoimmunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Inherited retinal dystrophy in Mer knockout mice.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Phagocytosis and clearance of apoptotic cells is mediated by MER.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

The induction of tolerance by dendritic cells that have captured apoptotic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Phagocyte recognition of cells undergoing apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Cloning and mRNA expression analysis of a novel human protooncogene, c-mer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Reevaluation of the roles of protein S and gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Cell death: the significance of apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Pancreatic islet-specific T-cell clones from nonobese diabetic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production.

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

An RCS-like retinal dystrophy phenotype in mer knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

Identification of Gas6 as a ligand for Mer, a neural cell adhesion molecule related receptor tyrosine kinase implicated in cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

Outer segment phagocytosis by cultured retinal pigment epithelial cells requires Gas6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

Subcongenic analysis of the Idd13 locus in NOD/Lt mice: evidence for several susceptibility genes including a possible diabetogenic role for beta 2-microglobulin.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Cloning and developmental expression analysis of the murine c-mer tyrosine kinase

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234377

Perforin and Fas induced by IFNγ and TNFα mediate beta cell death by OT-I CTL

21 September 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

MERTK polymorphisms associated with risk of haematological disorders among Korean SLE patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

Immunosuppressive effects of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062293

Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets

21 January 2018

1 reference

12 December 2020

Fine mapping of a QTL region with large effects on growth and fatness on mouse chromosome 2

1 reference

12 December 2020

Suppressor of cytokine signaling-1 regulates the sensitivity of pancreatic beta cells to tumor necrosis factor

1 reference

12 December 2020

Surfactant protein A enhances apoptotic cell uptake and TGF-beta1 release by inflammatory alveolar macrophages

1 reference

12 December 2020

Following a diabetogenic T cell from genesis through pathogenesis

1 reference

12 December 2020

CD8(+) T cell-mediated spontaneous diabetes in neonatal mice

1 reference

12 December 2020

Promotion of the uptake of PS liposomes and apoptotic cells by a product of growth arrest-specific gene, gas6

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20062293

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

18195070

1 reference