Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor (Q36443394)

14 August 2017

Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor (English)

1 reference

14 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7688468

19 August 2024

author name string

D. Bertrand

1

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19 August 2024

J. L. Galzi

2

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19 August 2024

A. Devillers-Thiéry

3

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19 August 2024

S. Bertrand

4

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19 August 2024

J. P. Changeux

5

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19 August 2024

language of work or name

English

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publication date

1 August 1993

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PMC publication ID

47057

full work available at URL

14 August 2017

http://www.pnas.org/content/90/15/6971.full.pdf

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https://europepmc.org/articles/PMC47057

19 August 2024

1 reference

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https://europepmc.org/articles/PMC47057?pdf=render

19 August 2024

1 reference

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https://pnas.org/doi/pdf/10.1073/pnas.90.15.6971

19 August 2024

1 reference

Crossref

DOI

10.1073/PNAS.90.15.6971

https://api.crossref.org/works/10.1073/PNAS.90.15.6971

Proceedings of the National Academy of Sciences of the United States of America

19 August 2024

published in

1 reference

14 August 2017

90

1 reference

14 August 2017

15

1 reference

14 August 2017

6971-6975

1 reference

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

The Diversity of Neuronal Nicotinic Acetylcholine Receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Ca2+ permeability of unedited and edited versions of the kainate selective glutamate receptor GluR6

30 September 2017

1 reference

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Acetylcholine receptor channel ionic selectivity: ions experience an aqueous environment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

The permeability of endplate channels to monovalent and divalent metal cations

30 September 2017

1 reference

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Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine

30 September 2017

1 reference

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The functional diversity of the neuronal nicotinic acetylcholine receptors is increased by a novel subunit: beta 4.

30 September 2017

1 reference

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Monovalent and divalent cation permeation in acetylcholine receptor channels. Ion transport related to structure

30 September 2017

1 reference

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Pharmacological and functional diversity of neuronal nicotinic acetylcholine receptors

30 September 2017

1 reference

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Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Alpha 5, alpha 3, and non-alpha 3. Three clustered avian genes encoding neuronal nicotinic acetylcholine receptor-related subunits

30 September 2017

1 reference

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The noncompetitive blocker [3H]chlorpromazine labels three amino acids of the acetylcholine receptor gamma subunit: implications for the alpha-helical organization of regions MII and for the structure of the ion channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Tris+/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Determinants of the calcium permeation of ligand-gated cation channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Molecular diversity of glutamate receptors and implications for brain function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Calcium conductance of acetylcholine-induced endplate channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Ion-concentration dependence of the reversal potential and the single channel conductance of ion channels at the frog neuromuscular junction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Mechanism of ion permeation through calcium channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Regulation of muscle AChR alpha subunit gene expression by electrical activity: involvement of protein kinase C and Ca2+.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Pharmacology of nicotinic receptor-mediated inhibition in rat dorsolateral septal neurones

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Existence of different subtypes of nicotinic acetylcholine receptors in the rat habenulo-interpeduncular system

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Calcium permeability of neuronal nicotinic acetylcholine receptor channels in PC12 cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

The effect of subunit composition of rat brain GABAA receptors on channel function

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Identification by mutagenesis of a Mg(2+)-block site of the NMDA receptor channel

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Nicotinic receptors that bind α-bungarotoxin on neurons raise intracellular free ca2+

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Calcium influx through nicotinic receptor in rat central neurons: its relevance to cellular regulation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Stratified organization of the nicotinic acetylcholine receptor channel

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47057

A patch clamp study of the nicotinic acetylcholine receptor of bovine adrenomedullary chromaffin cells in culture

21 September 2018

1 reference

12 December 2020

Intracellular calcium and desensitization of acetylcholine receptors

1 reference

12 December 2020

Chloride current induced by injection of calcium into Xenopus oocytes

1 reference

12 December 2020

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

1 reference

12 December 2020

Location of a threonine residue in the α -subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel

1 reference

12 December 2020

Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel

1 reference

12 December 2020

Cholinergic inhibition of short (outer) hair cells of the chick's cochlea

1 reference

12 December 2020

Protein kinase C couples membrane excitation to acetylcholine receptor gene inactivation in chick skeletal muscle

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.90.15.6971

1 reference

14 August 2017

0 references

1 reference

PMC publication ID

47057

14 August 2017

1 reference

PMC publication ID

47057