Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation (Q36437652)

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English	Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8612202%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8612202%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

experimental autoimmune encephalomyelitis

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K Gijbels

1

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15 October 2019

S Brocke

2

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15 October 2019

J S Abrams

3

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15 October 2019

L Steinman

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15 October 2019

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1 November 1995

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15 October 2019

Molecular Medicine

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15 October 2019

1

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15 October 2019

7

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15 October 2019

795-805

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15 October 2019

Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii.

1 reference

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30 September 2017

Interleukin-6 in biology and medicine

1 reference

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30 September 2017

Autoimmune disease

1 reference

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30 September 2017

Interleukin 6 promotes murine lupus in NZB/NZW F1 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

30 September 2017

Antibody against interleukin-6 reduces inflammation and numbers of cysts in brains of mice with toxoplasmic encephalitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

30 September 2017

Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

30 September 2017

Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients

1 reference

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30 September 2017

Interleukin-6 (IL-6) and acute phase proteins in the disease course of patients with systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

30 September 2017

Elevated levels of interleukin-6 in serum and cerebrospinal fluid of HTLV-I-associated myelopathy/tropical spastic paraparesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

30 September 2017

Interleukin-6 is elevated in plasma in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

30 September 2017

Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

30 September 2017

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

28 June 2018

Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

28 June 2018

Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

28 June 2018

Murine anti-human IL-6 monoclonal antibody prolongs the half-life in circulating blood and thus prolongs the bioactivity of human IL-6 in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

28 June 2018

Astrocyte activation correlates with cytokine production in central nervous system of Trypanosoma brucei brucei-infected mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

28 June 2018

Expression of interleukin (IL)-1 beta, IL-6 and their respective receptors in the normal rat brain and after injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

28 June 2018

High amounts of circulating interleukin (IL)-6 in the form of monomeric immune complexes during anti-IL-6 therapy. Towards a new methodology for measuring overall cytokine production in human in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

28 June 2018

Protective effect of anti-interleukin (IL)-6 antibody against endotoxin, associated with paradoxically increased IL-6 levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

28 June 2018

Limited involvement of interleukin-6 in the pathogenesis of lethal septic shock as revealed by the effect of monoclonal antibodies against interleukin-6 or its receptor in various murine models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

28 June 2018

Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230023

21 October 2018

Elevated levels of the 26K human hybridoma growth factor (interleukin 6) in cerebrospinal fluid of patients with acute infection of the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/8612202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides

1 reference

https://pubmed.ncbi.nlm.nih.gov/8612202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8612202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADP-ribosyltransferase activity of pertussis toxin and immunomodulation by Bordetella pertussis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8612202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8612202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8612202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased circulating interleukin-6 (IL-6) activity in endotoxin-challenged mice pretreated with anti-IL-6 antibody is due to IL-6 accumulated in antigen-antibody complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8612202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies chaperone circulating IL-6. Paradoxical effects of anti-IL-6 "neutralizing" antibodies in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8612202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/8612202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF03401894

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8612202%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8612202%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8612202%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

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