Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts (Q36399967)

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English	Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts	scientific article

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8 February 2020

Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts (English)

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8 February 2020

Deborah V Novack

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8 February 2020

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Viviana Cremasco

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8 February 2020

Corinne E Decker

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8 February 2020

Deborah Stumpo

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8 February 2020

Perry J Blackshear

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8 February 2020

Keiichi I Nakayama

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8 February 2020

Keiko Nakayama

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8 February 2020

Traian S Lupu

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8 February 2020

Daniel B Graham

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8 February 2020

Roberta Faccio

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8 February 2020

publication date

1 December 2012

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8 February 2020

Journal of Bone and Mineral Research

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8 February 2020

27

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8 February 2020

12

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8 February 2020

2452-2463

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8 February 2020

Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy

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30 September 2017

Spatial regulation of membrane fusion controlled by modification of phosphoinositides

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30 September 2017

Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Cortical F-actin, the exocytic mode, and neuropeptide release in mouse chromaffin cells is regulated by myristoylated alanine-rich C-kinase substrate and myosin II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Synaptotagmin VII regulates bone remodeling by modulating osteoclast and osteoblast secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Phospholipase Cgamma2 modulates integrin signaling in the osteoclast by affecting the localization and activation of Src kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

The osteoclast: friend or foe?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Cytoskeletal control of vesicle transport and exocytosis in chromaffin cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Skeletal remodeling in health and disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Genetic regulation of osteoclast development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Secretory granule exocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Formation and function of the ruffled border in osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Secretory lysosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

A nonsense mutation in the cathepsin K gene observed in a family with pycnodysostosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Interaction of myristoylated alanine-rich protein kinase C substrate (MARCKS) with membrane phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

The MARCKS family of cellular protein kinase C substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

MARCKS deficiency in mice leads to abnormal brain development and perinatal death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

The osteoclast clear zone is a specialized cell-extracellular matrix adhesion structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Polarized secretion of lysosomal enzymes: co-distribution of cation-independent mannose-6-phosphate receptors and lysosomal enzymes along the osteoclast exocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

30 September 2017

Disruption of the Man‐6‐P Targeting Pathway in Mice Impairs Osteoclast Secretory Lysosome Biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

28 June 2018

Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

28 June 2018

Inhibition of actin polymerization by latrunculin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

28 June 2018

Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

28 June 2018

Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

28 June 2018

Mitochondrial calcium sequestration and protein kinase C cooperate in the regulation of cortical F-actin disassembly and secretion in bovine chromaffin cells.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1701

21 January 2018

Chromaffin cell cortical actin network dynamics control the size of the release-ready vesicle pool and the initial rate of exocytosis

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1701

21 January 2018

Chromaffin cell F-actin disassembly and potentiation of catecholamine release in response to protein kinase C activation by phorbol esters is mediated through myristoylated alanine-rich C kinase substrate phosphorylation

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1701

21 January 2018

Role of alpha(v)beta(3) integrin in osteoclast migration and formation of the sealing zone.

1 reference

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21 September 2018

Endocytic pathway from the basal plasma membrane to the ruffled border membrane in bone-resorbing osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498518

21 September 2018

Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1701

21 January 2018

Phosphorylation, high ionic strength, and calmodulin reverse the binding of MARCKS to phospholipid vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/22806935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of diacylglycerols on osteoclastic bone resorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/22806935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/22806935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunolocalization of beta 3 subunit of integrins in osteoclast membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/22806935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/JBMR.1701

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22806935%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PMC publication ID

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8 February 2020

PubMed publication ID

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Europe PubMed Central

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8 February 2020

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