CD33 modulates TREM2: convergence of Alzheimer loci. (Q36381165)

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25 February 2020

title

CD33 modulates TREM2: convergence of Alzheimer loci (English)

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25 February 2020

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25 February 2020

Joseph M Replogle

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25 February 2020

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Philip L De Jager

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25 February 2020

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Elizabeth M Bradshaw

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25 February 2020

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Charles C White

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25 February 2020

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Lori B Chibnik

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25 February 2020

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David A Bennett

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25 February 2020

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Julie A Schneider

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25 February 2020

author name string

Gail Chan

1

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25 February 2020

Phoebe A Winn

3

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25 February 2020

Laura R Glick

6

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25 February 2020

Nicole E Cuerdon

7

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25 February 2020

Katie J Ryan

8

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25 February 2020

Keith A Johnson

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25 February 2020

Reisa A Sperling

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25 February 2020

language of work or name

English

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publication date

28 September 2015

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25 February 2020

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25 February 2020

volume

18

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25 February 2020

issue

11

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25 February 2020

page(s)

1556-1558

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TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

25 February 2020

cites work

1 reference

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TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

30 September 2017

1 reference

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A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology

30 September 2017

1 reference

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Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's disease

30 September 2017

1 reference

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TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

30 September 2017

1 reference

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Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

30 September 2017

1 reference

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Missense variant in TREML2 protects against Alzheimer's disease

30 September 2017

1 reference

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CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility

30 September 2017

1 reference

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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

30 September 2017

1 reference

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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

30 September 2017

1 reference

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Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

30 September 2017

1 reference

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GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

TREM2 Variants in Alzheimer's Disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

Overview and findings from the rush Memory and Aging Project

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

Overview and findings from the religious orders study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

A genome-wide scan for common variants affecting the rate of age-related cognitive decline

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

METAL: fast and efficient meta-analysis of genomewide association scans

30 September 2017

1 reference

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The role of microglia in amyloid clearance from the AD brain

30 September 2017

1 reference

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Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

30 September 2017

1 reference

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The TREM receptor family and signal integration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

Association studies of 19 candidate SNPs with sporadic Alzheimer's disease in the North Chinese Han population.

30 September 2017

1 reference

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Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

28 June 2018

1 reference

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The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4682915

Screening of the SOD1, FUS, TARDBP, ANG, and OPTN mutations in Korean patients with familial and sporadic ALS

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNN.4126

21 January 2018

Identifiers

DOI

10.1038/NN.4126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414614%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414614%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

PubMed publication ID

26414614

1 reference