Metabolic state signalling through central hypocretin/orexin neurons. (Q36346477)

PubMed publication ID

13 August 2017

1 reference

title

Metabolic state signalling through central hypocretin/orexin neurons (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740127&resulttype=core&format=json

12 May 2020

author name string

Denis Burdakov

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740127&resulttype=core&format=json

12 May 2020

Haris Alexopoulos

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740127&resulttype=core&format=json

12 May 2020

publication date

1 October 2005

1 reference

PubMed publication ID

16364191

Journal of Cellular and Molecular Medicine

13 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740127&resulttype=core&format=json

12 May 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740127&resulttype=core&format=json

12 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740127&resulttype=core&format=json

12 May 2020

page(s)

795-803

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740127&resulttype=core&format=json

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

12 May 2020

cites work

1 reference

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The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

21 January 2018

1 reference

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Identification of neurons containing orexin-B (hypocretin-2) immunoreactivity in limbic structures

21 January 2018

1 reference

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Distribution of orexin neurons in the adult rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Differential expression of orexin receptors 1 and 2 in the rat brain

21 January 2018

1 reference

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The hypocretins: setting the arousal threshold

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

21 January 2018

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Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

21 January 2018

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The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

21 January 2018

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Reduced number of hypocretin neurons in human narcolepsy

21 January 2018

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A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

21 January 2018

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Hypocretin (orexin) deficiency in human narcolepsy.

21 January 2018

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Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity

21 January 2018

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Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

21 January 2018

1 reference

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The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders.

21 January 2018

1 reference

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The sleep switch: hypothalamic control of sleep and wakefulness

21 January 2018

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Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Hypocretin/orexin depolarizes and decreases potassium conductance in locus coeruleus neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Orexins (hypocretins) directly excite tuberomammillary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Orexins/hypocretins excite basal forebrain cholinergic neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Orexins activate histaminergic neurons via the orexin 2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Hypocretin (orexin) induces calcium transients in single spines postsynaptic to identified thalamocortical boutons in prefrontal slice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Orexigen-sensitive NPY/AgRP pacemaker neurons in the hypothalamic arcuate nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Non-sleep effects of hypocretin/orexin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

The orexin/hypocretin system: a critical regulator of neuroendocrine and autonomic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Food intake in rhesus monkeys following central administration of orexins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Behavioral correlates of activity in identified hypocretin/orexin neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Regulation of orexin neurons by the monoaminergic and cholinergic systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Low-voltage-activated A-current controls the firing dynamics of mouse hypothalamic orexin neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

The wake-promoting hypocretin/orexin neurons change their response to noradrenaline after sleep deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Insulin-induced hypoglycemia increases preprohypocretin (orexin) mRNA in the rat lateral hypothalamic area

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Hypothalamic orexin expression: modulation by blood glucose and feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Orexin a preferentially excites glucose-sensitive neurons in the lateral hypothalamus of the rat in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Hypothalamic orexin neurons regulate arousal according to energy balance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Extracellular glucose in rat ventromedial hypothalamus during acute and recurrent hypoglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Neuronal glucosensing: what do we know after 50 years?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Glucose-sensing neurons: are they physiologically relevant?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Do neurons have a voltage or a current threshold for action potential initiation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Input organization and plasticity of hypocretin neurons: possible clues to obesity's association with insomnia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Meal Composition and Its Effect on Postprandial Sleepiness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

A comparison of feeding to cephalic stimulation on postprandial sleepiness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Influences of fat and carbohydrate on postprandial sleepiness, mood, and hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Debunking a myth: neurohormonal and vagal modulation of sleep centers, not redistribution of blood flow, may account for postprandial somnolence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Orexin neurons function in an efferent pathway of a food-entrainable circadian oscillator in eliciting food-anticipatory activity and wakefulness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Lowering glucose concentrations increases cytosolic Ca2+ in orexin neurons of the rat lateral hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Narcolepsy: a key role for hypocretins (orexins)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Increased body-mass index in patients with narcolepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Hypocretin deficiency in Prader-Willi syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

The number of hypothalamic hypocretin (orexin) neurons is not affected in Prader-Willi syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Hypocretin/orexin innervation and excitation of identified septohippocampal cholinergic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Orexins/hypocretins cause sharp wave- and theta-related synaptic plasticity in the hippocampus via glutamatergic, gabaergic, noradrenergic, and cholinergic signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Effects of orexin-A on memory processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Orexin-saporin lesions of the medial septum impair spatial memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

A role for lateral hypothalamic orexin neurons in reward seeking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2005.TB00380.X

Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system

21 January 2018

1 reference

12 December 2020

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

1 reference

12 December 2020

Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus.

1 reference

12 December 2020

Direct and indirect excitation of laterodorsal tegmental neurons by Hypocretin/Orexin peptides: implications for wakefulness and narcolepsy

1 reference

12 December 2020

Differential activation of orexin neurons by antipsychotic drugs associated with weight gain.

1 reference

12 December 2020

Hypocretin increases impulse flow in the septohippocampal GABAergic pathway: implications for arousal via a mechanism of hippocampal disinhibition.

1 reference

12 December 2020

Selective action of orexin (hypocretin) on nonspecific thalamocortical projection neurons.

1 reference

12 December 2020

Convergent excitation of dorsal raphe serotonin neurons by multiple arousal systems (orexin/hypocretin, histamine and noradrenaline).

1 reference

12 December 2020

Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions.

1 reference

12 December 2020

The wake-promoting hypocretin-orexin neurons are in an intrinsic state of membrane depolarization.

1 reference

12 December 2020

1 reference

12 December 2020

Orexin excites GABAergic neurons of the arcuate nucleus by activating the sodium--calcium exchanger.

1 reference

12 December 2020

Exclusive postsynaptic action of hypocretin-orexin on sublayer 6b cortical neurons

1 reference

12 December 2020

Eating and its relationships with subjective alertness and sleep in narcoleptic subjects living without temporal cues

1 reference

12 December 2020

Carbohydrates, tryptophan, and behavior: a methodological review

1 reference

12 December 2020

Plasma glucose and insulin profiles in normal subjects ingesting diets of varying carbohydrate, fat, and protein content

1 reference

12 December 2020

Extracellular glucose concentration in mammalian brain: continuous monitoring of changes during increased neuronal activity and upon limitation in oxygen supply in normo-, hypo-, and hyperglycemic animals

1 reference

12 December 2020

Neurons containing hypocretin (orexin) project to multiple neuronal systems

1 reference

12 December 2020

Independent feeding and metabolic actions of orexins in mice

1 reference

12 December 2020

Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and endocrine regulations

1 reference

12 December 2020

10.1111/J.1582-4934.2005.TB00380.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740127&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740127&resulttype=core&format=json

12 May 2020

PubMed publication ID

16364191

1 reference