Two novel DXZ4-associated long noncoding RNAs show developmental changes in expression coincident with heterochromatin formation at the human (Homo sapiens) macrosatellite repeat (Q36342867)

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English	Two novel DXZ4-associated long noncoding RNAs show developmental changes in expression coincident with heterochromatin formation at the human (Homo sapiens) macrosatellite repeat	scientific article

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19 February 2020

Two novel DXZ4-associated long noncoding RNAs show developmental changes in expression coincident with heterochromatin formation at the human (Homo sapiens) macrosatellite repeat (English)

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19 February 2020

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19 February 2020

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Debbie M Figueroa

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19 February 2020

Brian P Chadwick

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19 July 2015

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19 February 2020

Chromosome Research

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733-752

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19 February 2020

The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation

1 reference

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A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping

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30 September 2017

Small RNA expression from the human macrosatellite DXZ4.

1 reference

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30 September 2017

Noncoding RNAs and epigenetic mechanisms during X-chromosome inactivation.

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Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice

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30 September 2017

Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre

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30 September 2017

TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine.

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30 September 2017

X chromosome inactivation and epigenetic responses to cellular reprogramming

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30 September 2017

Genome-wide analysis of macrosatellite repeat copy number variation in worldwide populations: evidence for differences and commonalities in size distributions and size restrictions

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RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

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An integrated encyclopedia of DNA elements in the human genome

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30 September 2017

The mouse DXZ4 homolog retains Ctcf binding and proximity to Pls3 despite substantial organizational differences compared to the primate macrosatellite

1 reference

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30 September 2017

The macrosatellite DXZ4 mediates CTCF-dependent long-range intrachromosomal interactions on the human inactive X chromosome.

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Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.

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A long ncRNA links copy number variation to a polycomb/trithorax epigenetic switch in FSHD muscular dystrophy

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30 September 2017

Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution

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30 September 2017

New and Xisting regulatory mechanisms of X chromosome inactivation

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30 September 2017

DUX4 activates germline genes, retroelements, and immune mediators: implications for facioscapulohumeral dystrophy.

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30 September 2017

Uncovering the role of 5-hydroxymethylcytosine in the epigenome

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30 September 2017

YY1 associates with the macrosatellite DXZ4 on the inactive X chromosome and binds with CTCF to a hypomethylated form in some male carcinomas

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5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging

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Concise review: Pluripotency and the transcriptional inactivation of the female Mammalian X chromosome

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Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells

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30 September 2017

5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells

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30 September 2017

Variation in Array Size, Monomer Composition and Expression of the Macrosatellite DXZ4

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30 September 2017

Characterization of DXZ4 conservation in primates implies important functional roles for CTCF binding, array expression and tandem repeat organization on the X chromosome

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Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

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Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

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30 September 2017

Expression, tandem repeat copy number variation and stability of four macrosatellite arrays in the human genome

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A unifying genetic model for facioscapulohumeral muscular dystrophy

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30 September 2017

Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD).

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The D4Z4 macrosatellite repeat acts as a CTCF and A-type lamins-dependent insulator in facio-scapulo-humeral dystrophy.

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DXZ4 chromatin adopts an opposing conformation to that of the surrounding chromosome and acquires a novel inactive X-specific role involving CTCF and antisense transcripts

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Barring gene expression after XIST: maintaining facultative heterochromatin on the inactive X.

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Histone H3 lysine 4 methylation patterns in higher eukaryotic genes

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Hypomethylation of D4Z4 in 4q-linked and non-4q-linked facioscapulohumeral muscular dystrophy

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Role of histone H3 lysine 27 methylation in X inactivation

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X-chromosome inactivation and human genetic disease

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10.1007/S10577-015-9479-3

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19 February 2020

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19 February 2020

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